William Rutherford Sanders (1828-1881), anatomist, physician, linguist and museum conservator.

William Rutherford Sanders spent a childhood and early student days divided between Edinburgh and Montpelier, France before graduating in Medicine in Edinburgh. An early interest in the spleen was encouraged by a two-year period in Europe where he became familiar with the work of Helmholtz, Bernard and Henle. Returning to Edinburgh, his growing experience led to the position of assistant in the Infirmary pathology department. He conducted classes in the University of Edinburgh and on behalf of the Royal Colleges became familiar with the museum of the Royal College of Surgeons where he was chosen as Conservator in 1853. Criticised by 20th century historians for concentrating on verbal teaching rather than on the conservation of the museum, Sanders became a consultant physician to the Royal Infirmary in 1861 and in 1869 Professor of General Pathology. Throughout these years, Sanders gave as much time as possible to the study of the structure and function of the spleen and to neurological disorders such as hemiplegia. His later life was interrupted by a series of illnesses commencing with an abdominal abscess. A prolonged convalescence allowed the resumption of work but deranged vision and hemiplegia preceded his death on 18 February 1881.

Henry Wade (1876-1955), pioneer of urological surgery, museum conservator and war veteran.

Henry Wade graduated in the Edinburgh Medical School in 1898 before spending two years with the British army during the Anglo-Boer war. Returning to this country, he joined Francis Caird, surgeon to the Edinburgh Royal Infirmary. Appointed Conservator of the museum of the Royal College of Surgeons of Edinburgh, Wade met young William Ford Robertson. In a study of experimental cancer they concluded that some neoplasms were caused by bacteria. Wade became increasingly recognised as an authority in urology. His growing practice was interrupted by the First World War. Already a member of the Royal Army Medical Corps, he served for five years in the Middle East, in Gallipoli and then with the army in an approach to Jerusalem. Resuming civilian life, Wade combined an extensive urological practice with membership of the Council of the RCSEd. He became President in 1935. Married in 1924, his wife died four years later after an operation by a colleague, David Wilkie. Director of Surgery to the Scottish Emergency Medical Service when the Second World War broke out, Wade was made a Knight Bachelor in 1946. He died in 1955.

James Bell Pettigrew (1832-1908) MD, LLD, FRS, comparative anatomist, physiologist and aerobiologist.

After leaving Glasgow University, Pettigrew joined the Edinburgh Medical School in 1856. Professor Goodsir determined Pettigrew's entire future by awarding him the Anatomy Gold Medal for an essay on cardiac muscle. The essay was accompanied by dissections of such high quality that they led to the Croonian Lecture of the Royal Society of London in 1860. After graduating, Pettigrew's time as House Surgeon to James Syme was followed by a position in the Hunterian Museum, London. Intensive studies of urinary and alimentary muscle, and observations of insects and animals, with lectures on flight to distinguished societies, contributed to disabling illness and a long convalescence but in 1869 Pettigrew became Conservator of the Royal College of Surgeons of Edinburgh and then Pathologist to the Royal Infirmary of Edinburgh. The publication of Physiology of the Circulation and of Animal Locomotion, with its emphasis on aeronautics, ensured international fame. Fellowship of both London and Edinburgh Royal Societies was another factor contributing to Pettigrew's election to the Chandos Chair at St Andrews University in 1875. The construction and abortive flying of a motor-driven aeroplane came near the end of his life and Pettigrew gave his remaining years to completing his monumental Design in Nature.

John Goodsir FRS (1814-1867): Pioneer of cytology and microbiology.

John Goodsir, pioneer of the concept that all tissues are formed of cells, was born in 1814 into a family of medical practitioners in Anstruther, Fife, Scotland where he was captivated by the marine life he saw daily in his childhood. His ambition was to follow his father and grandfather in medicine. Aged 13, he studied at St Andrews University before being apprenticed to an Edinburgh dentist and completing an original analysis of the embryology of human dentition. He became the student of Robert Knox at the Royal College of Surgeons of Edinburgh and then Conservator of the University Anatomy museum. He exchanged this position for one at the College of Surgeons before accepting the full University post. Beginning in 1830 with the compound microscope, he studied natural history and anatomy, describing his discoveries to many societies. Appointed to the Edinburgh Chair of Anatomy in 1846, his investigations of the cell as the unit of all tissues were recognised internationally. A critic of Darwin, he believed that Man could not evolve. However, malnutrition, the death of a brother and of a friend and collaborator, Edward Forbes, contributed to progressive illness and Goodsir died at Wardie, Edinburgh in 1867.