RESUMEN
A facile one-pot synthesis of novel steroidal dispiro-indenoquinoxaline pyrrolidines via multicomponent-[3+2]-cycloaddition of azomethine ylides in ionic liquid is described. The structure of cycloadduct is confirmed by IR, (1)H NMR, (13)C NMR, high resolution mass spectroscopy and elemental analysis.
Asunto(s)
Líquidos Iónicos/química , Pirrolidinas/química , Compuestos de Espiro/química , Esteroides/química , Esteroides/síntesis química , Técnicas de Química SintéticaRESUMEN
In the title compound, [Fe(C(5)H(5))(C(32)H(26)N(3)O)], the pyrrolidine ring adopts a twist conformation. The indeno-quinoxaline ring system [86.44â (5)°], the methyl-phenyl ring [86.06â (7)°] and the ferrocene rings [82.00â (7) and 83.95â (9)°] are almost perpendicular to the pyrrolidine ring. The two cyclopentadienyl rings adopt an eclipsed conformation. The crystal structure features C-Hâ¯N inter-actions.
RESUMEN
In the title compound, [Fe(C5H5)(C31H24N3O)], the pyrrolidine ring adopts a twist conformation. The pyrrolidine ring is almost perpendicular to the indeno-quinoxaline ring system, making a dihedral angle of 84.44â (5)°. The cyclo-penta-dienyl rings of the ferrocene moiety adopt an eclipsed conformation. The crystal packing features weak C-Hâ¯N and C-Hâ¯π inter-actions.
RESUMEN
In the title compound, [Fe(C(5)H(5))(C(31)H(24)N(3)O)], the pyrrolidine ring makes a dihedral angle of 86.3â (3)° with the mean plane [r.m.s deviation = 0.074â (2)â Å] of the indeno-quinoxaline ring system. The central pyrrolidine ring adopts a twist conformation and the two cyclopentadienyl rings adopt an eclipsed conformation. In the crystal, mol-ecules are linked by weak C-Hâ¯N and C-Hâ¯π inter-actions, propagating along the c and a axes, respectively.
RESUMEN
In the title compound, C(32)H(25)NO(2)S(2), the mean plane through the five-membered pyrrolidine ring, which exhibits an envelope conformation, makes dihedral angles of 82.3â (1) and 83.9â (9)° with the benzene ring and the acenaphthyl-ene ring system, respectively. The dihedral angle between the thiophene rings is 19.0(3)°. The crystal structure shows C-Hâ¯π and π-π inter-actions [centroid-centroid distance = 3.869â (2)â Å].
RESUMEN
In the title compound, C(31)H(22)ClNO(2)S(2), the five-membered pyrrolidine ring, which exhibits an envelope conformation, makes a dihedral angle of 87.4â (2)° with the acenaphthyl-ene ring system. The crystal structure is stabilized by π-π inter-actions [centroid-centroid distance = 3.869â (2)â Å]. A C atom and the S atom of the thiophene ring are disordered over two positions with refined occupancies of 0.629â (7) and 0.372â (7).