Asunto(s)
Infecciones por Coronavirus , Neumonía Viral , Aspirina , Betacoronavirus , COVID-19 , Femenino , Humanos , Pandemias , Embarazo , SARS-CoV-2Asunto(s)
Crisis Blástica/patología , Médula Ósea/patología , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico , Anciano , Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Biomarcadores , Biopsia , Femenino , Pruebas Genéticas , Humanos , Inmunofenotipificación , Leucemia-Linfoma Linfoblástico de Células Precursoras/metabolismo , Leucemia-Linfoma Linfoblástico de Células Precursoras/terapia , Recurrencia , Resultado del TratamientoRESUMEN
This paper presents to the surgical community an unusual and often ignored cause of gastrointestinal bleeding. Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is a rare medical entity characterized by phagocytosis of red blood cells, leucocytes, platelets, and their precursors in the bone marrow by activated macrophages. When intestinal bleeding is present, the management is very challenging with extremely high mortality rates. Early diagnosis and treatment seem to be the most important factors for a successful outcome. We present two cases and review another 18 from the literature.
Asunto(s)
Donantes de Sangre , Seguridad de la Sangre , Hematoma/epidemiología , Síncope/epidemiología , Adulto , Factores de Edad , Anciano , Femenino , Hematoma/etiología , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Factores de Riesgo , Suiza/epidemiología , Síncope/etiologíaRESUMEN
We report a case of a young man presenting with a severe neutropenia together with a mild anemia. The diagnostic work up of such a hematological anomaly is reviewed. It finally revealed a therapy-related acute myeloid leukemia, secondary to previous chemotherapy for a testicular tumor.