1.
Chem Commun (Camb)
; 60(15): 2062-2065, 2024 Feb 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38288752
RESUMEN
Here, we present a synthetic route towards γ-amino alcohols with continuous stereocenters based on a copper-catalyzed asymmetric conjugate addition/CO2-trapping tandem reaction of α,ß-unsaturated amide, followed by a reduction of the generated α-carboxyl amide. This strategy provides a green route for the transformation of CO2 into valuable chiral organic molecules.