RESUMEN
Talents are the main force for the development of traditional Chinese medicine（TCM）， and the construction of TCM talents and the reformation of talent evaluation system are essential to promote the inheritance and innovation of TCM. At present， we are still exploring and developing in the fields of the formulation， implementation and evaluation indicators of TCM talent evaluation system. However， there are shortcomings and difficulties. For instance， insufficient stratification in the evaluation， excessive emphasis on the quantity of achievements， neglecting the quality of the achievements and the actual contribution， imperfect assessment indicators， and the weak characteristics of TCM. Therefore， national ministries and commissions have jointly issued a document requesting to break the four only and set a new standard， in order to promote the construction of a scientific and technological talent evaluation system oriented by innovation value， ability and contribution. For the evaluation of TCM clinical talents， China Association for Science and Technology commissioned China Association of Chinese Medicine to build the China Clinical Cases Library of TCM（CCCL-TCM）， which aims at collecting the most authoritative and representative TCM clinical cases and exploring the advantages of applying clinical cases as masterpiece of achievement in TCM clinical talents evaluation. CCCL-TCM can promote the construction of a talent evaluation system that is more in line with the development characteristics of TCM industry， and to carry out relevant pilot in TCM colleges and institutions across the country in order to promote the reformation of TCM talent evaluation system.
RESUMEN
Membranous nephropathy， an autoimmune kidney disease with glomerular podocyte injury as the core mechanism， is a common pathological type of adult nephrotic syndrome and has become the main cause of end-stage renal disease in China. Podocytes are terminally differentiated cells that play an important role in maintaining the structural and functional stability of glomeruli and are molecular barriers for protein filtration. Glomerular filtration membrane injury induced by podocyte injury is an important cause of massive proteinuria. Persistent or aggravated proteinuria may prolong the course of membranous nephropathy. It is believed that podocyte destruction in membranous nephropathy is mainly related to oxidative stress， autophagy dysregulation， abnormal expression of podocyte marker proteins， chronic inflammation， epithelial-mesenchymal cell transdifferentiation， and so on. At present， western medicine mostly uses immunosuppressants and hormones for treatment according to its pathological stage， but there are certain adverse reactions. Traditional Chinese medicine （TCM） has made some achievements in the prevention and treatment of membranous nephropathy. In recent years， studies have found that many Chinese medicines can affect the occurrence and development of membranous nephropathy in different links by acting on multiple targets in the human body， with manifest advantages. This paper overviewed the podocyte injury mechanism in membranous nephropathy and summarized the treatment of membranous nephropathy with Chinese medicine monomers， compounds， and Chinese patent medicines in intervening related target pathways， aiming to provide a basis for the clinical treatment， basic research， and targeted drug development of TCM against membranous nephropathy.
RESUMEN
[Objective]To analyze the meaning of"body pain is like being punished with a rod"in Synopsis of the Golden Chamber·Yin Yang Pestilences,so as to better understand the meaning of Zhongjing.[Methods]By using the research method of combining the handed-down literature with the textual research of unearthed cultural relics,combining with the perspective of character and history,and there is one proved case attached.[Results]"Body pain is like being punished with a rod"is a vivid expression that people describe their personal experience."Rod"can be understood as"anything that can be held is called a rod"."Being punished with a rod"is divided into three cases including skin is swollen and bruised;damage occurs;dead by being punished.Pain may be caused by trauma(skin and muscle)or internal injury(viscera injury).Shengma Biejia Decoction is mainly used to detoxify and disperse evil,promote blood circulation,and give consideration to both Qi and blood.[Conclusion]In the era of Zhongjing,"body pain is like being punished with a rod"has a certain degree of differentiation,which is reflected in the differentiation of the way of applying the rod and the painful feeling.This paper discusses the concept of"body pain is like being punished with a rod"by combining literature and cultural relics research,so that readers can intuitively understand the meaning of Zhongjing in the social background at that time,and also provides a new way to learn Synopsis of the Golden Chamber.
RESUMEN
Diabetic kidney disease(DKD)is one of the common chronic complications of diabetes mellitus(DM),the primary cause of chronic kidney disease(CKD),including end-stage renal disease(ESRD),and an important risk factor for early death in diabetic patients.As an important starting point of DKD,diabetic tubulopathy(DT)is important for the early prevention and treatment of DKD.It is found that traditional Chinese medicine can effectively delay the course of DKD through the active prevention and treatment of DT,and achieve early prevention,early treatment and good prognosis.The mechanism is mainly to improve and protect the damaged renal tubules in patients in various periods through different targets and pathways,so as to reduce kidney injury,improve the clinical symptoms of patients and delay the course of the disease.This paper reviews the mechanism of renal tubular injury in diabetic kidney disease and the progress of traditional Chinese medicine in the prevention and treatment of diabetic kidney disease based on diabetic tubulopathy in recent years.