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Adv Biol (Weinh) ; 7(12): e2300142, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-37423961

RESUMEN

A functional immune system is crucial for a healthy life, protecting from infections, tumors, or autoimmune disorders; these are accomplished by the interaction between various immune cells. Nourishment, particularly micronutrients, are very important components in the immune system balance, therefore this review emphasizes the vitamins (D, E, A, C) and Dendritic cells' subsets due to vitamins' roles in immune processes, especially on dendritic cells' functions, maturation, and cytokine production. Current studies reveal significant benefits related to vitamins, including vitamin E, which can contribute to the control of dendritic cells' function and maturation. Furthermore, vitamin D plays an immunoregulatory and anti-inflammatory role in the immune system. Metabolite of vitamin A which is called retinoic acid leads to T cells' differentiation to T helper 1 or T helper 17, so low levels of this vitamin exacerbate the menace of infectious diseases, and vitamin C has anti-oxidant effects on dendritic cells and modulate their activation and differentiation program. Additionally, the correlation between the amount of vitamin and the occurrence or progression of allergic diseases and autoimmunity disorders is discussed according to the results of previous studies.


Asunto(s)
Hipersensibilidad , Vitaminas , Humanos , Vitaminas/farmacología , Vitaminas/uso terapéutico , Vitamina A/farmacología , Vitamina A/uso terapéutico , Vitamina D/metabolismo , Vitamina D/uso terapéutico , Vitamina K , Hipersensibilidad/tratamiento farmacológico , Células Dendríticas/metabolismo
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