RESUMEN
BACKGROUND: Male-pattern hair loss (androgenetic alopecia) is a common clinical condition in adult men that is often associated with negative self-perception and has been the target of a number of therapeutic interventions. Despite the importance of self-perceptions of hair growth and appearance with such interventions, nostandardized valiated questionnaire exists for use in clinical trials. OBJECTIVE: DEvelop and evaluate a questionnaire to measure patients-perceived changes in hair growth and appearance in clinical trials of medical intervention for androgenetic alopecia in emen. METHODS: Literature review and focus groups with men having androgenetic alopecia initially identified 28 potential questions. These questions were assessed in an observational study (n=204) and placebo-controled seven global questions addressing change since the start of the study in satisfaction with hair appearance (three questions), hair growth and appearance, size of the bald spot, and slowing of hair loss. Significant differences favoring active treatment over placebo were evident for all seven questions by months in a clinical trial. CONCLUSIONS: This standardized questionnaire can be used to assess patient perceptions of hair growth in clinical trials of men with androgenetic alopecia