RESUMEN
Using data from the COMPASS-ND study we investigated associations between hearing loss and hippocampal volume as well as cortical thickness in older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's dementia (AD). SCD participants with greater pure-tone hearing loss exhibited lower hippocampal volume, but more cortical thickness in the left superior temporal gyrus and right pars opercularis. Greater speech-in-noise reception thresholds were associated with lower cortical thickness bilaterally across much of the cortex in AD. The AD group also showed a trend towards worse speech-in-noise thresholds compared to the SCD group.
RESUMEN
Thermal decomposition under both air and inert atmospheres of a commercial Mancozeb product was investigated through thermogravimetric analysis and laboratory scale thermal treatment from 20°C to 950°C, with analysis of gaseous and solid products. The aim of this study is the understanding of the thermal degradation mechanisms of a pesticide under different atmospheres and the chemical identification of the solid and gaseous pollutants which can be emitted during warehouse fires and which can constitute a threat for health and environment. Pyrolysis of Mancozeb takes place between 20°C and 950°C and lead essentially to CS(2) and H(2)S emissions with formation at 950°C of MnS and ZnS. Thermal oxidation of Mancozeb under air occurs between 150°C and 950°C with formation of CO, CO(2) and sulphur gases (CS(2) and SO(2)). The first step (155-226°C) is the loss of CS(2) and the formation of ethylene thiourea, ZnS and MnS. The metallic sulphides are oxidized in ZnO and MnSO(4) between 226°C and 650°C (steps 2 and 3). MnSO(4) is then oxidized in Mn(3)O(4) during the last step (step 4) between 650°C and 950°C. At 950°C, carbon recovery is close to 95%. Sulphur recovery is close to 98% with an equal partition between SO(2) and CS(2).