Walking the talk for dementia: A unique immersive, embodied, and multi-experiential initiative.

Coping with dementia requires an integrated approach encompassing personal, health, research, and community domains. Here we describe "Walking the Talk for Dementia," an immersive initiative aimed at empowering people with dementia, enhancing dementia understanding, and inspiring collaborations. This initiative involved 300 participants from 25 nationalities, including people with dementia, care partners, clinicians, policymakers, researchers, and advocates for a 4-day, 40 km walk through the Camino de Santiago de Compostela, Spain. A 2-day symposium after the journey provided novel transdisciplinary and horizontal structures, deconstructing traditional hierarchies. The innovation of this initiative lies in its ability to merge a physical experience with knowledge exchange for diversifying individuals' understanding of dementia. It showcases the transformative potential of an immersive, embodied, and multi-experiential approach to address the complexities of dementia collaboratively. The initiative offers a scalable model to enhance understanding, decrease stigma, and promote more comprehensive and empathetic dementia care and research.

The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science.

Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or declining rates in North America and Europe. This scenario places unprecedented clinical, social, and economic burden upon patients, families, and health systems. The challenges prove particularly pressing for conditions with highly specific diagnostic and management demands, such as frontotemporal dementia. Here we introduce a research and networking initiative designed to tackle these ensuing hurdles, the Multi-partner consortium to expand dementia research in Latin America (ReDLat). First, we present ReDLat's regional research framework, aimed at identifying the unique genetic, social, and economic factors driving the presentation of frontotemporal dementia and Alzheimer's disease in Latin America relative to the US. We describe ongoing ReDLat studies in various fields and ongoing research extensions. Then, we introduce actions coordinated by ReDLat and the Latin America and Caribbean Consortium on Dementia (LAC-CD) to develop culturally appropriate diagnostic tools, regional visibility and capacity building, diplomatic coordination in local priority areas, and a knowledge-to-action framework toward a regional action plan. Together, these research and networking initiatives will help to establish strong cross-national bonds, support the implementation of regional dementia plans, enhance health systems' infrastructure, and increase translational research collaborations across the continent.

Case report: Respiratory syncytial virus / Caso clínico: virus sincicial respiratorio

Background: The Respiratory Syncytial Virus (RSV) is the most important viral pathogen in children under 2 years of age, which warrants hospitalization for a low respiratory infection. 0.5% of children under 5 with RSV infection require hospitalization. The aim of this case is to reaffirm the importance of this virus as a cause of severe disease and to emphasize the importance of adequate diagnosis and management to improve prognosis. Clinical case: Child of 1 year 3 months old, without risk factors for severe infection by respiratory viruses. A 3-day course of respiratory failure, requiring mechanical ventilation with a pulmonary protection strategy due to the development of intra-pulmonary ARDS, was considered a mixed infection and received antibacterial treatment. During his hospitalization, RSV infection was documented. He was graduated without pulmonary sequelae. Conclusions: Respiratory syncytial virus is the respiratory virus that causes a greater burden of disease, even above influenza. Unfortunately for children without risk factors for severe infection there are no options for prevention or treatment, so in subjects with severe disease the only option is the management of support in specialized units and the timely detection of bacterial overinfection. The development of a vaccine is necessary.

Introducción: El virus sincicial respiratorio (VSR) es el patógeno viral más importante en niños menores de 2 años que ameritan hospitalización por infección respiratoria baja. Un 0.5% de los menores de 5 años con infección por VSR requiere ingreso hospitalario. El objetivo de este caso es reafirmar la importancia de este virus como causa de cuadros graves y recalcar la importancia de un diagnóstico y manejo adecuados para mejorar el pronóstico. Caso clínico: Paciente de 1 año 3 meses de edad, sin factores de riesgo para infección grave por virus respiratorios. Padecimiento de 3 días de evolución hacia falla respiratoria, requirió ventilación mecánica con estrategia de protección pulmonar por desarrollo de SDRA intrapulmonar, se consideró infección mixta por lo que recibió tratamiento antibacteriano, durante su hospitalización se documentó infección por VSR. Fue egresado sin secuelas pulmonares. Conclusiones: El virus sincicial respiratorio es el virus respiratorio que ocasiona mayor carga de la enfermedad, incluso por arriba de influenza. Desafortunadamente, para los niños sin factores de riesgo para infección grave no hay opciones de prevención ni de tratamiento, por lo que en los sujetos con enfermedad grave la única opción es el manejo de soporte en unidades especializadas y la detección oportuna de sobreinfección bacteriana. Es necesario el desarrollo de una vacuna.

Frecuencia de trastornos oftalmológicos comunes en población preescolar de una delegación de la Ciudad de México / Frequency of common ophthalmological abnormalities among preschool children in Mexico City

Objetivo. Conocer la frecuencia de las alteraciones oftalmológicas más comunes en un grupo de niños preescolares de la Delegación Coyoacán de la Ciudad de México. Material y métodos. De un total de 93 escuelas de preescolares se seleccionaron 39 en forma aleatoria. Médicos pediatras practicaron un examen oftalmológico a 343 niños. Se obtuvieron frecuencias simples e intervalos de confianza de las frecuencias en los diferentes grupos y de cada uno de los trastornos. Resultados. De los 343 niños, 57 (16.6 por ciento) presentaron trastornos visuales; cuantro tenían estrabismo, cuatro catarata, uno glaucoma y 48 errores de refracción. Sólo 3.8 por ciento (13) habían sido valorados previamente. Conclusiones. Consideramos que la frecuencia encontrada es suficientemente significativa para promover y fomentar la detección oportuna de algunos trastornos oftalmológicos y disminuir el número de casos con diagnósticos tardíos

Objective. To estimate the prevalence of undetected vision abnormalities among preschool children. These problems can lead to a variety of adverse consequences, the most serious being amblyopia, wich becomes irreversible after the fifth year without treatment. In some other countries there are screening programs to identify visual abnormalities among four year old children. In our country there are no studies about the prevalence of this problem among preschool children. Material and methods. A total of 39 preschool children were randomly selected from 93 kindergarten schools in a District of Mexico City. In total, 343 children were screened for ophthalmologic abnormalities by two pediatricians who were previously trained for this purpose. Results. Fifty seven (16.6%) children failed the visual acuity testing: four had strabismus, four cataract, and one glaucoma, and 48 refraction defects. Only 13 (3.8%) had been previously examined, ever. Conclusions. We consider that the prevalence found supports the recommendation to promote ophthalmologic examining as part of the routinary child care practice and to perform preventive preschool screening.