RESUMEN
This pilot study aimed to evaluate the long-term effects of Whole-Body Vibration (WBV) on hind limb muscles, gait and pain in lame dogs with borderline-to-severe hip dysplasia. Ten lame client-owned dogs with borderline-to-severe hip dysplasia, aged from 1.5 to 9.0 years and weighing 14.5 to 53.0 kg, were enrolled. The WBV training program consisted of 15 min sessions three times weekly for 16 weeks. Muscles of the hind limbs were evaluated using measurements of thigh circumference, the cross-sectional thickness of selected hind limb muscles by ultrasound assessment, and vastus lateralis muscle activity determined by surface electromyography (EMG). Lameness and clinical signs of pain were assessed by visual lameness scoring, orthopedic examination and an owner-based questionnaire. Kinetic analysis was performed by using a pressure-sensitive walkway. Manual thigh circumference measurements of both hind limbs showed significant increases over the trial period with a greater degree of change observed after week 8. Ultrasound measurements of the left gluteal muscles and the quadriceps femoris muscles of both hind limbs showed significant increases in the cross-section thickness post WBV. Owner's perception of pain also showed a decrease in signs of pain at week 12 and week 16 compared to baseline. Based on graphs of the EMG activity patterns of the vastus lateralis muscle, 65% of the hind limbs had an improvement after 48 WBV sessions when compared to pre-session patterns. However, no significant differences were observed in visual lameness evaluation and kinetic analysis. Therefore, further studies will help to better clarify the role of WBV in canine rehabilitation protocols.
RESUMEN
O presente relato teve como objetivo descrever um caso de leucemia linfocítica B em um cão da raça maltês, fêmea, com três anos de idade, demonstrando a metodologia de diagnóstico e a variação da patologia clínica após o tratamento exclusivamente por esplenectomia. A linfocitose acentuada observada no hemograma e presença proliferativa de linfócitos na medula óssea determinou a suspeita da leucemia linfocítica. A leucemia linfocítica B foi diagnosticada por meio da citologia aspirativa da medula óssea, imunocitoquímica e citometria de fluxo. O tratamento foi exclusivamente por esplenectomia e dois anos após a cirurgia o animal não apresentou recidiva da afecção.
This report aimed to describe a case of B lymphocytic leukemia in maltese female dog, three years old, demonstrating the methodology of diagnostic and variation of clinical pathology after treatment exclusively by splenectomy. The accentuate lymphocytes observed in blood counts and presence of proliferative lymphocytes in the bone marrow were determined to diagnostic of lymphocytic leukemia. The B lymphocytic leukemia was diagnosed by bone marrow aspiration cytology, immunocytochemistry and flow cytometry. The treatment was exclusively by splenectomy and two years after the surgery the animal showed no recurrence of the disease.
El objetivo de ese relato ha sido describir un caso de leucemia linfocítica B en un perro, raza maltés, hembra, de tres años, demostrando la metodología de diagnóstico y la variación de la patología clínica, después del tratamiento exclusivamente por esplenectomía. La linfocitosis aguda, observada en el hemograma, y la presencia de proliferación de linfocitos en la médula ósea, determinó la sospecha de leucemia linfocítica. La leucemia linfocítica B fue diagnosticada mediante la citología por aspiración de médula ósea, inmunocitoquímica y citometría de flujo. El tratamiento fue exclusivamente por esplenectomía y dos años después de la cirugía el animal no mostró recurrencia de la enfermedad.
