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Background: Assessment of oral epithelial dysplasia is the gold standard for investigating the risk of malignant progression. The World Health Organization (WHO) methods and the binary system have limitations. This study assess the inter- and intra-observer variability of the architectural and cytological criteria and the classification of the presence and degree of epithelial dysplasia in oral lichen planus (OLP) and oral lichenoid lesion (OLL), using both the 2017 WHO criteria and the binary system. Material and Methods: The sample consisted of 65 biopsies from lesions classified as OLP and OLL according to the American Academy of Oral and Maxillofacial Pathology (AAOMP) criteria. The histological slides were reevaluated by two oral pathologists. Results: The individual alterations with most inter-observer disagreement were atypical mitotic figures (43.1%), loss of cohesion between epithelial cells (38.5%) and drop shape rete ridges ridges (38.5%). Inter-observer agreement analysis did not show statistically significant agreement regarding the classification of epithelial dysplasia grade by WHO criteria, only regarding the binary system classification (k=0.257; p=0.035). Intra-observer agreement analysis by evaluator 1 showed that the classification of epithelial dysplasia grade according to both methods had statistically significant agreement (k=0.546; p=0.004, k=0.861; p<0.001). Considering evaluator 2, only the evaluation of the WHO system classification showed statistically significant agreement (k=0.593; p=0.010). Conclusions: The evaluation of epithelial dysplasia is subjective and focal changes and inflammatory infiltrate, characteristic of OLP and OLL, can increase the degree of disagreement among evaluators. The binary system presents better inter-observer agreement, while the WHO system presents better intra-observer agreement. Key words:Oral lichen planus, oral lichenoid lesion, oral lichenoid disease, dysplasia, inter-observer variation.
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Objetivo: Descrever os conhecimentos sobre o beijo na boca e sua possibilidade de transmissão de doenças infecciosas em um grupo de adolescentes de escolas privadas de Nova Iguaçu/Rio de Janeiro, através deste estudo piloto. Metodologia: Estudo seccional em que foi aplicado um roteiro de perguntas semi-estruturado autoaplicável em adolescentes (de 18 e 19 anos) de ambos os gêneros, pertencentes a três escolas da rede de ensino privado do município de Nova Iguaçu no Estado do Rio de Janeiro. Resultados: De um total de 100 adolescentes que participaram deste estudo, mais da metade eram solteiros e do gênero feminino (61%), apenas estudantes como ocupação (88% do total) e 96% já haviam beijado na boca. A amostra selecionada demonstrou características próprias, com a alta frequência do conhecimento da possibilidade de transmissão de doenças infecciosas pelo beijo na boca e saliva (71%), que possivelmente se confirmou pela baixa ocorrência de lesões após o ato do beijo e pela observação da boca do parceiro antes de beijar. Conclusão: A pratica do beijo na boca e o sexo oral devem ser temáticas consideradas na assistência fornecida a adolescentes. O uso de estratégias preventivas e o acesso às redes sociais podem contribuir para a redução de situações de risco advindos de situações de vulnerabilidade.
Aim: To describe the knowledge about the kiss on the mouth and its possibility of transmission of infectious diseases in a group of adolescents from private schools in Nova Iguaçu / Rio de Janeiro, through this pilot study. Methodology: Cross-sectional study in which a self-administered semi-structured question script was applied to adolescents (18 and 19 years) of both genders, belonging to three schools of the private school system of Nova Iguaçu, Rio de Janeiro State. Results: Of a total of 100 adolescents who participated in this study, more than half were single and female (61%), only students as occupation (88% of the total) and 96% had already kissed the mouth. The selected sample demonstrated its own characteristics, with the high frequency of the knowledge of the possibility of transmission of infectious diseases by kissing in the mouth and saliva (71%), which was possibly confirmed by the low occurrence of lesions after the kiss and the observation of the mouth. of the partner before kissing. Conclusion: The practice of kissing on the mouth and oral sex should be thematic considered in the care provided to adolescents. The use of preventive strategies and access to social networks can contribute to the reduction of risk situations arising from vulnerability situations. Keywords: mouth, infectious diseases, adolescent (s), health education, strategies and oral health
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Humanos , Masculino , Femenino , Adolescente , Adulto , Salud Bucal , Educación en Salud , Enfermedades Transmisibles , Estrategias de Salud , Conducta del Adolescente , BocaRESUMEN
Objetivo: Avaliar as alterações químicas presentes na superfície metálica de limas endodônticas fraturadas em canais radiculares, in vitro, após a inoculação intrarradicular de culturas de BRS de três cepas microbianas, Desulfovibrio desulfuricans (uma cepa oral e outra ambiental) e Desulfovibrio fairfieldensis. Métodos: foram analisadas 5 limas kerr #90, sendo uma Lima Kerr nova, sem tratamento, e as outras 4 limas fraturadas dentro de canais radiculares in vitro, com posterior inoculação de Desulfovibrio desulfuricans, cepa oral e ambiental, e Desulfovibrio fairfieldensis e um grupo controle sem inoculação bacteriana, por 477 dias. Os grupos foram analisados no modo EDS (Espectrometria de Energia Dispersiva de Raios-x) do microscópio eletrônico de varredura (FEI-Inspect-S50). Resultados:A presença do S, Cl e O foram relacionados ao processo biocorrosivo, assim como a redução dos elementos de liga nesta área. Conclusão:As análises no modo EDS demonstraram biocorrosão ao longo da superfície metálica das limas quando empregado o biofármaco BACCOR, nas três diferentes cepas empregadas, indicada pela redução dos elementos formadores da liga metálica, Fe, Ni e Cr, com a associação da presença de elementos indicadores de biocorrosão como O, Cl e S. (AU)
Aim:To evaluate the chemical alterations present on the metallic surface of root canal fractured endodontic files in vitro after the intraradicular inoculation of BRS cultures of three microbial strains, Desulfovibrio desulfuricans (one oral and one environmental strain), and Desulfovibrio fairfieldensis. Methods: Five kerr #90 files were analyzed, one new untreated Kerr file and the other 4 files fractured within root canals in vitro, with a subsequent inoculation of Desulfovibrio desulfuricans (oral and environmental strains), and Desulfovibrio fairfieldensis, as well as a control group without bacterial inoculation for 477 days. The groups were analyzed using the scanning electron microscope (FEI-Inspect-S50) EDS (X-ray Dispersive Energy Spectrometry) mode. Results:The presence of S, Cl, and O were related to the biocorrosive process, as well as the reduction of alloying elements in this area. Conclusion: The EDS mode analysis showed biocorrosion along the metallic surface of the files when the BACCOR biopharmaceutical was used in the three different strains employed in this study, indicated by the reduction of the alloying elements Fe, Ni, and Cr with the association of the presence of indicator elements of biocorrosion, such as O, Cl, and S. (AU)
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Productos Biológicos , Corrosión , Medios de Cultivo , Aleaciones Dentales , Instrumentos Dentales , Desulfovibrio desulfuricans , Cavidad Pulpar , Desulfovibrio , Técnicas In Vitro , EndodonciaRESUMEN
Objective: The aim of this study was to compare dental color changes after a one-session tooth bleaching procedure using 35% hydrogen peroxide with and without hybrid light (LED/diode laser) activation. Material and Methods: 20 volunteers were included in a split-mouth controlled clinical trial. A 35% hydrogen peroxide gel was applied directly on the buccal surface and adjacent areas of all upper anterior teeth. The six teeth were divided into two groups: the upper right incisors and canine were submitted to the tooth bleaching with the gel and the hybrid light (LED/diode laser) while the left incisors and canine were submitted to tooth bleaching with only the gel. Dental color was measured with a visual color scale and a spectrophotometer at five different moments: initial appointment, immediately after prophylaxis, and 14, 30 and 180 days after bleaching. Results: The comparison between the results of both treatments (with and without LED/laser) did not show any statistically significant differences (p > 0.05; Wilcoxon test) neither for objective (spectrophotometer) nor for subjective evaluations (visual color scale). Conclusion: The results of the present study showed that there are no differences in dental color changes between dental bleaching with gel and LED/Laser activation and dental bleaching with only gel.
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Resumo Objetivo Estimar se variáveis clínicas e epidemiológicas influenciam no atraso do diagnóstico em dois centros de referência. Métodos Foi realizado um estudo analítico longitudinal retrospectivo. Todos os prontuários de pacientes maiores de 18 anos diagnosticados no período de junho de 2005 a junho de 2013 foram analisados por meio do SPSS® 20. Para testar associações entre as variáveis epidemiológicas e clínicas com os atrasos do paciente e do profissional, foram utilizados os testes: ANOVA, t de Student e Kruskal-Wallis. Resultados Foram incluídos no estudo 121 prontuários. Prevaleceram pacientes do sexo masculino, com idade média de 64,3 anos (DP=12,94), pardos, procedentes do interior, analfabetos, tabagistas e etilistas. A grande maioria (85,1%) foi diagnosticada nos estádios avançados. O maior atraso estava relacionado ao paciente, com média de tempo de 197,8 dias (DP=323,9). O atraso no diagnóstico profissional foi de 20 dias (DP=25,9), e aquele relacionado ao sistema de saúde foi de 71,1 dias (DP=71,7). Não houve associação entre as variáveis clínicas/epidemiológicas e o atraso no diagnóstico (do paciente e do profissional). Conclusão De acordo com os resultados do presente estudo, as variáveis clínicas e epidemiológicas não influenciam no atraso do diagnóstico.
Abstract Objectives To analyze the chronology of diagnosis and determine whether clinical and epidemiological variables have an influence on diagnostic delay at two referral centers. Methods The medical records of all patients older than 18 years diagnosed with oral/oropharyngeal cancer from June 2005 to June 2013 were analyzed using SPSS® 20. The association between epidemiological and clinical variables with patient and professional delay was performed using ANOVA, Student’s t-test, and Kruskal-Wallis test. Results In total, 121 medical records were included in the study. Patients were predominantly brown, male, illiterate, living in country towns, smokers, and heavy drinkers (mean age 64.3 years, SD=12.94). The majority (85.1%) of patients were diagnosed at advanced stages of their disease. The greatest delay was patient-related, mean 197.8 days (SD=323.9). Delay in establishing the medical diagnosis averaged 20 days (SD=25.9), and health care system-related delay was 71.1 days (SD=71.7). There was no association of clinical and epidemiological variables with delayed diagnosis (patient and professional). Conclusion Data from the present study suggest that clinical and epidemiological variables do not influence diagnostic delay.
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Abstract Oral complications of RA may include temporomandibular joint disorders, mucosa alterations and symptoms of dry mouth. The aim of this study was to evaluate the salivary gland function of subjects with rheumatoid arthritis (RA) comparing it to healthy controls. Subjects with other systemic conditions known to affect salivary functions were excluded. A questionnaire was applied for the evaluation of xerostomia. Resting and chewing-stimulated salivary flow rates (SFR) were obtained under standard conditions. There were 145 subjects included of the study (104 RA and 38 controls). About 66.7% of the RA subjects and 2.4% in control group presented xerostomia. The median resting SFR were 0.24 ml/min for RA subjects and 0.40 mL/min for controls (p = 0.04). The median stimulated SFR were 1.31 mL/min for RA subjects and 1.52 ml/min for controls (p = 0.33). No significant differences were found between resting and stimulated SFR of RA subjects not using xerogenic medications and controls. There was significantly higher number of subjects presenting hyposalivation in the RA group than among controls, even when subjects using xerogenic medications were eliminated from the analysis. In conclusion, hyposalivation and xerostomia were more frequent among RA subjects not using xerogenic medication than among controls, although there were no significant differences in the median SFR between groups.
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Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Adulto Joven , Artritis Reumatoide/fisiopatología , Artritis Reumatoide/tratamiento farmacológico , Glándulas Salivales/efectos de los fármacos , Glándulas Salivales/fisiopatología , Glándulas Salivales/metabolismo , Salivación/efectos de los fármacos , Salivación/fisiología , Tasa de Secreción/efectos de los fármacos , Tasa de Secreción/fisiología , Xerostomía/inducido químicamente , Estudios de Casos y Controles , Factores Sexuales , Encuestas y Cuestionarios , Estadísticas no Paramétricas , Antirreumáticos/efectos adversos , Persona de Mediana EdadRESUMEN
OBJECTIVE: The purpose of this study was to estimate the prevalence of periradicular lesions in HIV-infected Brazilian patients and to assess the correlation of several factors with the periradicular status. METHOD: One hundred full-mouth periapical radiographs were evaluated. A total of 2,214 teeth were evaluated for the presence of periradicular lesions, caries lesions, coronal restorations, pulp cavity exposure and endodontic treatment. RESULTS: The prevalence of periradicular lesions was 46%. There were no significant differences between individuals with or without periradicular lesions with respect to their socio-demographic status, habits, laboratory data and route of HIV infection. However, the presence of a periradicular lesion was statistically correlated with the number of teeth with endodontic treatment (p = 0.018), inadequate endodontic treatment (p = 0.025), images suggesting pulp cavity exposure (p = 0.002) and caries lesions (p = 0.001). CONCLUSIONS: The prevalence of periradicular lesions in HIV-infected individuals was 46% and was not related to HIV infection. .