RESUMEN
Objective To evaluate the efficacy and safety of combined use of insulated-tip knife, titanium clips and transparent caps in the resection of large pedunculated colorectal polyps. Methods Therapeutic method: with the assistance of transparent cap, 1~3 titanium clip(s) were applied to the base of the stalk to block blood supply of large polyps and then insulated-tip knife was utilized to resect polyps by cutting the stalk. Research method: retrospectively analyze the clinical data of 45 large pedunculated colorectal polyps (head ≥ 2.0 cm) which were treated by the method mentioned above from January 2014 to December 2015. Statistics of procedure time, clip numbers, complication rates were used to assess the effect of the treatment. Results 45 large polyps were successfully removed one time without any severe complications of bleeding or perforation during procedure except a very small amount of blood were oozing from the cutting edge in 3 cases. There were also no delayed complications of bleeding or perforation after procedure. The average number of titanium clip was 2.7 and the average operating time was (5.7 ± 1.2) min (range 3 ~ 12 min). Conclusion Combined application of insulated-tip knife, titanium clips and transparent cap inthe resection of large pedunculated colorectal polyps is safe, effective and convenient to conduct.
RESUMEN
Objective To evaluate the efficacy and safety of combined use of insulated-tip knife, titanium clips and transparent caps in the resection of large pedunculated colorectal polyps. Methods Therapeutic method: with the assistance of transparent cap, 1~3 titanium clip(s) were applied to the base of the stalk to block blood supply of large polyps and then insulated-tip knife was utilized to resect polyps by cutting the stalk. Research method: retrospectively analyze the clinical data of 45 large pedunculated colorectal polyps (head ≥ 2.0 cm) which were treated by the method mentioned above from January 2014 to December 2015. Statistics of procedure time, clip numbers, complication rates were used to assess the effect of the treatment. Results 45 large polyps were successfully removed one time without any severe complications of bleeding or perforation during procedure except a very small amount of blood were oozing from the cutting edge in 3 cases. There were also no delayed complications of bleeding or perforation after procedure. The average number of titanium clip was 2.7 and the average operating time was (5.7 ± 1.2) min (range 3 ~ 12 min). Conclusion Combined application of insulated-tip knife, titanium clips and transparent cap inthe resection of large pedunculated colorectal polyps is safe, effective and convenient to conduct.
RESUMEN
OBJECTIVE: To compare different processing technologies of Aconiti Kusnezoffii Radix, and to optimize a kind of "low toxicity and high efficiency", simple and practical processing technology for Aconiti Kusnezoffii Radix. METHODS: HPLC method was used to determine the content of six kinds of alkaloids, and titration method to determine the content of total alkaloids. These contents combined with production were used to evaluate the modern processing technologies of Aconiti Kusnezoffii Radix. RESULTS: There was serious drain of Aconitum alkaloids after treated by soaking, and the loss rates of the content of monoester alkaloids, diester alkaloids and total alkaloid were 20.97%, 31.13% and 14.57%, respectively. The content of alkaloids could maximize the retention using wetting method, the best methods for reducing poison were atmospheric pressure and high pressure steaming cooking methods, and its total diester alkaloids content was too low to be detected, the contents of alkaloids in samples of two kinds of high-temperature baking were 0.6903 mg/g and 0.5575 mg/g, which were higher than the requirement of Chinese Pharmacopoeia. The content of monoester alkaloids was 0.6336 - 2.2721 mg/g of 10 kinds of processing technologies, between which there were nine kinds of processing technologies beyong the Chinese Pharmacopoeia requirement of 0.7 mg/g, while the total alkaloids content was 7.8019 - 11.2078 mg/g. CONCLUSION: The best method for reducing poison is high-pressure steaming, whose content of diester alkaloids can reach the Chinese Pharmacopoeia requirement after treatment of wet autoclaved products, with higher content of total alkaloids. It is simple, controllable, and suitable for processing of Aconiti Kusnezoffii Radix.
