[Nonsurgical and surgical management of osteoporotic vertebral body fractures : Recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU)]. / Nichtoperative und operative Behandlung der osteoporotischen Wirbelkörperfraktur : Empfehlungen der Sektion Wirbelsäule der Deutschen Gesellschaft für Orthopädie und Unfallchirurgie (DGOU).

STUDY DESIGN: Prospective clinical cohort study (data collection); expert opinion (recommendation development). OBJECTIVES: Treatment options for nonsurgical and surgical management of osteoporotic vertebral body fractures differ widely. Based on the current literature, the knowledge of the experts, and their classification for osteoporotic fractures (OF classification), the Spine Section of the German Society for Orthopaedics and Trauma has now introduced general treatment recommendations. METHODS: A total of 707 clinical cases from 16 hospitals were evaluated. An OF classification-based score was developed for guidance in the option of nonsurgical versus surgical management. For every classification type, differentiated treatment recommendations were deduced. Diagnostic prerequisites for reproducible treatment recommendations were defined: conventional X­rays with consecutive follow-up images (standing position whenever possible), magnetic resonance imaging, and computed tomography scans. OF classification allows for upgrading of fracture severity during the course of radiographic follow-up. The actual classification type is decisive for the score. RESULTS: A score of less than 6 points advocates nonsurgical management; in cases with more than 6 points, surgical management is recommended. The primary goal of treatment is fast and painless mobilization. Because of the expected comorbidities in this age group, minimally invasive procedures are preferred. As a general rule, stability is more important than motion preservation. It is mandatory to restore the physiological loading capacity of the spine. If the patient was in a compensated unbalanced state at the time of fracture, reconstruction of the individual prefracture sagittal profile is sufficient. The instrumentation technique has to account for compromised bone quality. We recommend the use of cement augmentation or high purchase screws. The particular situations of injuries with neurological impairment, the necessity to fuse, multiple level fractures, consecutive and adjacent fractures and fractures in ankylosing spondylitis are addressed separately. CONCLUSIONS: The therapeutic recommendations presented here provide a reliable and reproducible basis to decide for the treatment choices available. However, intermediate clinical situations with a score of 6 points remain, allowing for both nonsurgical and surgical options. As a result, individualized treatment decisions may still be necessary. In the subsequent step, the recommendations presented will be further evaluated in a multicentre controlled clinical trial.

Percutaneous vertebral augmentation in fragility fractures-indications and limitations.

INTRODUCTION: There is still no general consensus about the management of osteoporotic vertebral fractures. Recommendations depend on type of fracture, grade of instability, bone quality, and general conditions of the patient. Spontaneous fractures may be considered to be treated different compared to cases with high-velocity trauma. METHODS: According to the DVO, patients without trauma should first be treated conservatively. However, there is no more strict time protocol of 3 or 6 week conservative treatment before operations may be indicated. Surgical criteria are not yet distinctly defined. For highly unstable fractures (type B and C according to the AO Spine Classification), posterior instrumentation with cement augmented screws and as long construct, respectively, is adequate. Current literature has been analysed for diagnostic and therapeutic protocols. RESULTS: There is no clear operative concept for burst fractures and classic osteoporotic fractures with dynamic ongoing sintering. Percutaneous vertebral augmentation showed to prevent the fractures from ongoing kyphotic deformity and the patients from painful immobilization. Indications and results of classical vertebroplasty and kyphoplasty have been discussed intensively in the literature. Further development included special injection techniques, cements with different viscosities and stenting systems to reach more stable constructs and avoid typical complications, such as cement extrusion. CONCLUSIONS: This review reports upon indications and limitations of percutaneous vertebral augmentation and the potential development of classifications and therapeutic algorithms.

[Intraoperative 3D imaging in spinal surgery]. / Intraoperative 3­D-Bildgebung in der Wirbelsäulenchirurgie.

BACKGROUND: Intraoperative imaging during spinal interventions has experienced significant developments over the last two decades. By the introduction of flat screen detectors, 3D imaging has been made possible and easier and by developing compact and mobile systems computed tomography can even be used in the operating theater. OBJECTIVE: Presentation of modern intraoperative 3D imaging and navigation in spinal surgery. MATERIAL AND METHODS: The techniques of intraoperative 3D imaging and navigation during spinal procedures are presented based on the currently available literature and own experiences at a German national spine and trauma center. RESULTS: The use of flat panel detectors and the possibility of 3D visualization nowadays substantially facilitate the use of navigation and allow certain control of surgical results even during the intervention. Radiation exposure of the whole team in the operating theater can be significantly reduced by the new techniques. CONCLUSION: The advantages of intraoperative 3D imaging with a clear improvement of visualization for spinal surgeons and the certain control of materials at the end of the operation are obvious. Even the use of navigation has been greatly simplified and can therefore lead to an even greater precision and less radiation exposure. There are even more sophisticated developments, such as operation suites and intraoperative computed tomography but these are initially reserved for selected centers.

[Imitation of an Anderson type II dens fracture by a motion artefact in computed tomography : Four case examples]. / Imitation einer Densfraktur Typ Anderson II durch ein computertomographisches Bewegungsartefakt : Vier Fallbeispiele.

Computed tomography (CT) is the method of choice in the diagnosis and classification of odontoid fractures with a sensitivity of more than 99 % and a specificity almost equally as high. In this article we report on four cases where CT-generated motion artefacts exactly mimicked an Anderson type II fracture of the dens axis, initially leading to a wrong diagnosis. Although this seems to be a very rare event, these cases indicate that overlooked CT motion artefacts can lead to severe consequences and attention must be paid to the radiological signs outlined in this report.

[Fractures of the thoracic and lumbar spine]. / Frakturen der Brust- und Lendenwirbelsäule.

Fractures of the thoracic and lumbar spine result from high velocity trauma, assuming bone density is normal. The main location of fractures is the thoracolumbar junction. Most injuries can be treated conservatively; however, patients transferred to hospitals and spine centers represent a preselection with more severe trauma and a higher incidence of operative treatment. There is a large variety of operative techniques that can be used, which can be principally differentiated by the approach: posterior or anterior. Dorsal approaches are differentiated by the instrumentation for spondylodesis as open or percutaneous techniques. Minimally invasive options are favored more and more. For osteoporotic bone, cement augmented solutions may be used. Correct reduction of mainly kyphotic malalignment is crucial for the long-term outcome. Biomechanically stable reconstruction of the anterior spinal column is important mainly for the thoracolumbar junction.

[Incomplete cranial burst fracture in the thoracolumbar junction. Results 6 years after thoracoscopic monosegmental spondylodesis]. / Kraniale inkomplette Berstungsfraktur im thorakolumbalen Übergang. 6-Jahres-Ergebnisse nach thorakoskopischer monosegmentaler Spondylodese.

INTRODUCTION: Ventral thoracoscopic spondylodesis of the thoracolumbar spine is an elegant treatment strategy. MATERIAL AND METHODS: In the years 2002 and 2003 a total of 16 patients with incomplete cranial burst fractures were treated by ventral thoracoscopic monosegmental spondylodesis and were included in this study prospectively. The data acquisition was done preoperatively, postoperatively and after 3, 6, 12 and 18 months. After 6 years a follow-up examination was performed in 13 of these patients (5 men and 8 women, average age 36.3 years, follow-up rate 81%) and 8 patients were treated ventrally only whereas 5 patients were treated dorsoventrally. RESULTS: The operative reduction of the kyphotic malalignment was superior in the dorsoventrally treated patients. The persistent gain of monosegmental correction after 6 years seemed to be higher in the patient group treated dorsoventrally. The average physical component summary (PSC) scores were comparable to a control group of the same age and revision surgery was performed in two patients both related to the iliac crest bone graft. CONCLUSIONS: The ventral and dorsoventral therapy strategies showed good and very good functional outcomes, respectively. The dorsoventral treatment concept secured a persistent gain of monosegmental correction which seemed to be superior compared to a ventral only therapy strategy.

[Repositioning options with percutaneous dorsal stabilization. For burst fractures of the thoracolumbar junction]. / Repositionsmöglichkeiten mittels perkutaner dorsaler Instrumentierung. Bei Berstungsfrakturen des thorakolumbalen Übergangs.

BACKGROUND: The purpose of this investigation was to evaluate the options of percutaneous systems for reducing relevant posttraumatic kyphosis in spinal burst fractures. Clinical advantages of percutaneous techniques are evident from the literature and a disadvantage can be a lack of repositioning options in reducing the fracture kyphosis. Better results seem to be possible with new techniques and especially monoaxial percutaneous screws. PATIENTS AND METHODS: A total of 70 patients with burst fractures (AO type Magerl A3.1-A3.3) of the thoracolumbar spine were treated with a special percutaneous reduction technique in the Trauma Clinic in Murnau (BGU) Germany between July 2009 and March 2011. Posttraumatic, intraoperative and postoperative kyphosis was measured in computed tomography (CT) scans in monosegmental and bisegmental angles. Two different percutaneous fixation systems were compared for reduction. Statistical analyses were carried out with Student's t-test. RESULTS: We found a highly significant difference between preoperative and postoperative kyphosis angles but no differences in reduction between the two percutaneous systems. In 39 cases additional reconstruction of the anterior column was necessary because of a ventral defect. In comparison to the MCS 2 study of the German Society of Trauma Surgery (DGU) we found no differences in postoperative kyphosis angles (3°). CONCLUSION: A significant reduction of posttraumatic kyphosis of thoracolumbar burst fractures is possible with percutaneous techniques. Prerequisites are percutaneous monoaxial screws and tools and a special percutaneous technique as described.

[Proximal tibial fractures sustained during alpine skiing - incidence and risk factors]. / Proximale Tibiafrakturen im Skisport - Inzidenz und Risikofaktoren.

BACKGROUND: Prior to introduction of carving skis, complex fractures of the proximal tibia were rarely seen. Recently these fractures are being seen more frequently in connection with alpine skiing. The aim of this study was to find out the incidence of proximal tibia fractures in alpine skiing and to identify possible risk factors. METHODS: All patients with proximal tibia fractures related to alpine skiing in a large German ski resort were included. Fracture type, patient and skiing related factors were recorded. Incidence of fractures was determined by using the number of all registered skiers. Multinomial logistic regression analysis was used to calculate the odds ratios for risk factors. RESULTS: Between 2007 and 2010 a total of 188 patients was treated for proximal tibia fractures caused by alpine skiing. Forty-three patients had a type-A injury, 96 patients a type-B injury, and 49 patients a type-C injury. The incidence of injury increased continuously, starting from 2.7 and climbing to 7.0 per 105 skiing days. The risk factors compared to patients with type-A fractures, type-C fracture occurred in older (OR 0.93; 0.89 - 0.97) and heavier (OR 0.86; 0.74 - 0.99) individuals and were more likely on icy snow conditions (OR 0.22; 0.05 - 0.96), higher speed (OR 0.29; 0.09 - 0.97) and skiing skill (OR 0.35; 0.13 - 0.95). These was also seen in artificial and icy snow conditions (OR 0.25; 0.07 - 0.87) when compared to type-B fractures. CONCLUSION: The incidence of proximal tibia fractures related to skiing has increased over the past four years. Risk factors such as age, BMI, snow conditions, speed, and the skill of the skiers, were identified as causes contributing to complex fractures.

[What is the effect of ventral thoracoscopic spondylodesis (VTS) on elderly patients and what is the medium-term outcome?]. / Die ventrale Spondylodese beim älteren Patienten--Overtreatment oder sinnvolle Therapieoption?

BACKGROUND: Only limited data are available concerning the effect of ventral thoracoscopic spondylodesis (VTS) on elderly patients and the medium-term outcome. MATERIAL AND METHOD: In a retrospective study, 23 patients were included from 2003 to 2008. An age over 60, a traumatic burst fracture in the thoracolumbar region and a VTS procedure were inclusion criteria. A preoperative neurological deficit, ASA scores greater than 3 and a malignant disease were exclusion criteria. The mean age was 65 (62-70) years, 17 male and 6 female patients were included. In 87 % (n = 18) of the patients a compression fracture type A was found. Bone density values were obtained in 5 patients, mean value was -1,7. 21 patients were treated with a dorsoventral, bisegmental procedure. Two patients with limited kyphosis and no relevant stenosis of the spinal canal were treated with a ventral only procedure. In two cases with measured low bone quality, pedicle screws were placed with bone cement. Patients were monitored on ICU for 24 hours after operation until the thoracic drainage was removed. At an average follow-up of 3.9 years, patients were evaluated with SF 36 (short form 36) and an Oswestry disability index score (ODI score). The postoperative radiographic control was performed with a CT scan, X-ray controls were taken 3, 6, 12 and 18 months after the operation. Cobb angle and scoliosis angle were measured. Statistical analysis was carried out with SPSS-Software 17.0 (SPSS®, Inc., Chicago, USA) and a Mann-Whitney U test and a level of significance of p < 0,05. RESULTS: In five patients pulmonary complications occurred, in one case a revision operation had to be performed due to pleural effusion. One patient suffered from a delayed pneumonia. The mean loss of correction in all patients was 3,3° (-20°-1°). In four patients with a distinct loss of correction at an average of 13,6° ± 4,5°, iatrogenic damage of the lower or upper cover plate of the adjacent vertebral bodies was found. The risk of loss of correction was found to be significantly higher in case of damage to the lower or upper cover plate (p < 0.001). Test results from the SF 36 score (sum scale 40.8) showed no significant difference in life quality to a similar aged comparison group. The ODI score revealed a mean vertebral column associated impairment of 10.8 %, 20 patients showed only minimal limitations. CONCLUSION: Also in older patients VTS seems to be an adequate treatment of traumatic burst fractures of the thoracolumbar spine. Perioperative pulmonary complications were easy to handle and had no effect on the clinical outcome. Postoperative radiographs showed only little loss of correction, in four cases iatrogenic damage of the cover-plate led to a distinct loss of correction. Careful and accurate preparation of the cover plates is therefore decisive.

[Long-term results of kyphoplasty with additive dorsal instrumentation of incomplete burst fractures of the thoracolumbar spine in the elderly]. / Langzeitergebnisse nach Hybridstabilisierung inkompletter Berstungsfrakturen der thorakolumbalen Wirbelsäule des älteren Patienten.

BACKGROUND: To offer a correct treatment strategy for osteoporotic vertebral body fractures remains a huge challenge in modern spine surgery. PATIENTS AND METHODS: In the years 2002 and 2003 5 patients with incomplete burst fractures (AO type A3.1) of the thoracolumbar spine were included in this study (4 men, 1 woman, average age: 62.6 years, follow-up rate: 100 %). All 5 were treated by kyphoplasty and additional dorsal bisegmental instrumentation. Unlike today, dorsal instrumentation was done without cement augmentation. Inclusion criteria were age above 60 years, an adequate trauma, and a fracture between thoracic body 11 and lumbar body 3. Data acquisition was performed prospectively before and after the operation, after 3, 6, 12, 18 months, and after 5 years, including visual analogue scale (VAS) spine score, spinal function score, X-ray examination or in cases of complaints or limited assessability a CT examination, and SF 36 score after 5 years. As comparison group, we used 4 patients, suffering the same fracture type with a similar fracture location (1 man, 3 women, average age: 67.3 years), who were treated with kyphoplasty alone during the same time period. RESULTS: No clinically relevant intra- and postoperative complications were registered in our study group. The operative bisegmental kyphotic reduction was slightly higher in our study group. Afterwards the correction loss was 9.8° in our study group, exceeding the reduction by 3.6°, whereas the comparison group suffered from a correction loss of 11.8°, exceeding the operative reduction by 8.5°, respectively. These differences were not statistically significant. Similarly, no statistically significant differences were registered with respect of physical component summary (PSC), mental component summary (MSC) score and VAS spine score. Both groups had comparable PSC and MSC scores to a norm group of the same age. CONCLUSION: After 5 years the therapy concept seems to be of low risk and not being associated with major complications. The PCS and MCS scores are comparable to a norm group of the same age. The correction loss exceeded the operative reduction marginally but turned out to be slightly lower compared to that of an isolated kyphoplasty.

[Reconstruction after spinal fractures in the thoracolumbar region]. / Rekonstruktion der ventralen Säule nach thorakolumbalen Wirbelsäulenverletzungen.

The morbidity of anterior approaches has significantly influenced the development of therapeutic concepts for the treatment of thoracolumbar spine fractures. Minimally-invasive techniques such as mini-open and endoscopic have enlarged the numbers of anterior reconstruction after spinal fractures in the thoracolumbar region. These minimally-invasive approaches have been facilitated by the development of special implants adapted to the new technique and to the local anatomical requirements.Two multi center studies in Germany (MCSI and II) showed the trend towards minimal invasive procedures and anterior approaches in the German speaking spine centers. Since the first report on thoracoscopic anterior procedures in Germany in 1997 a growing number of spine centers established this method. There is still no evidence based high level literature to substantiate a significant benefit for the patients by anatomical reduction and reconstruction of the anterior spinal column. However, there are some reports on better short outcomes in radiological parameters as well as better clinical results in 5 to 8 year follow-ups.The minimal invasive anterior approach seems to be advantageous for the patients by reducing significantly additive operation morbidity. It has become more important over the last two decades for anterior reconstruction after trauma and posttraumatic malalignment of the thoracolumbar spine.

O-arm(®)-based spinal navigation and intraoperative 3D-imaging: first experiences.

Since the first use of instrument-tracking techniques in the early 1990s, image-guided technologies became a leading topic in all branches of spine surgery. Today, navigation is a widely available tool in spine surgery and has become a part of clinical routine in many centers for a large variety of indications. Spinal navigation may not only contribute to more precision during surgery, but it may also reduce radiation exposure and fluoroscopy time, with advantages not only for the patient but also for the operating room personnel. Different registration algorithms have been developed differing in terms of the type of image data used by the navigation system (preoperatively acquired computed tomography [CT] images, intraoperatively acquired fluoroscopy images) and the way virtual and physical reality is matched. There is a tendency toward a higher accuracy for 3D fluoroscopy-based registration algorithms. The O-arm(®) represents a new flat-panel technology with the source and detector moving in a 360° arc around the patient. In combination with the Stealth(®) station system, navigation may start immediately after automated registration with already referenced instruments. After instrumentation, an additional scan may confirm intraoperatively the correct positioning of the instrumentation. The first experiences with the system are described in this paper.

[Treatment concepts for fractures of the thoracolumbar junction and lumbar spine]. / Therapiekonzepte bei Frakturen des thorakolumbalen Uberganges und der Lendenwirbelsäule.

Thoracolumbar vertebral fractures are not only characterized by frequent osteoligamentous instability, but also often by irreversible damage to to the intervertebral disk. Treatment guidelines can be formulated based on an accurate classification system. In addition to reconstructing the axis of rotation, it is crucial that the width of the spinal canal be restored when neurological deficits are present. Both indirect dorsal compression and ventral endoscopically guided direct decompression are equally of decisive importance. To achieve long-term stability with as little corrective loss as possible, the ventral column absorbing pressure is surgically stabilized by diligently resecting a destroyed intervertebral disk and vertebral fragments and replacing it with a corticocancellous bone graft or cage. The goal should always be to keep the fusion length as short as possible.

[Use of the "c-clamp" in the emergency treatment of unstable pelvic fractures]. / Notfallbehandlung instabiler Beckenfrakturen - Stellenwert der "Beckenzwinge"

UNLABELLED: It was the objective of this investigation to describe the results after stabilisation of pelvic fractures with the pelvic clamp in polytraumatized patients with unstable pelvic ring fractures. PATIENTS: Between 1999 and 2001 11 polytraumatized patients with an average age of 38 years with unstable fractures of the pelvic ring were treated with the "pelvic clamp" (PC). METHOD: The patient's data were analysed retrospectively from the moment they were admitted to our department until 48 hours after the treatment with the pelvic clamp. The following data were observed: -- The time period until the pelvic clamp was placed. -- The mean blood pressure. -- The oxygenation level (PaO (2)/FiO (2) coefficient). -- The number of requested blood units. -- The time period until hemodynamic stabilisation took place. RESULTS: 8 patients survived their injuries. 5 of them were admitted primarily to our department (ISS 39.8, PTS 35), the other 3 were secondarily admitted to our department (ISS 48.3, PTS 39). 3 of 11 patients (27 %) died averaged within the first 45 minutes after admittance. They also were treated in other units before admittance to our department. 8 surviving patients showed -- a hemodynamic stabilisation 6 hours after the treatment with the PC. -- an increase of the mean blood pressure about 25 % 20 minutes after the treatment with the PC. -- a stabilisation of the oxygenation level 6 hours after the treatment with the PC. -- a decrease of the number of requested blood units 6 hours after treatment with the PC. CONCLUSION: Even if the number of patients who were treated is small, the study shows a positive trend in terms of stabilisation of the vital parameters after stabilisation of the pelvic fracture with the pelvic clamp.

[Ankle arthrodesis with intramedullary compression nailing]. / Die Technik der tibiotalaren Arthrodese mit Kompressionsmarknagel.

Tibiotalar arthrodesis still remains the primary choice of treatment for disabling ankle arthropathy since the results of ankle arthroplasty are not yet convincing. Numerous operative techniques have been described, with an increasing trend towards the use of internal fixation and compression. Using an intramedullary compression nailing technique, 137 tibiotalar fusions were performed at our hospital. The special design of the nail allows distal interlocking in the talus and dynamic axial compression with high primary stability. With correct joint axis, only the cartilage joint surfaces were removed. For axis correction the corresponding bony joint surfaces were also resected. We also performed a dowel technique with bone grafting from the lateral malleolus. We examined 110 of the 137 patients during follow-up. A primary union could be achieved in 99 cases (90.0%). A further six cases (5.5%) healed after recompression and bone grafting. Nonunion remained in five cases (4.5%). Operative complications included one tibial shaft fracture and one hematoma. Septic complications were three superficial and eight deep infections. Sufficient pain relief after arthrodesis was reported by 70 (63.6%) patients; in 37 (33.6%) patients the symptoms remained unchanged and 3 (2.7%) patients found their pain to be worse than before the procedure. Intramedullary compression nailing is shown to be an effective technique for tibiotalar arthrodesis in severe ankle arthropathy. The main advantages of the technique are limited soft tissue damage in the ankle area and high primary stability allowing early weight bearing.

[Thoracolumbar spine fractures after conservative and surgical treatment. Dependence of correction loss on fracture level]. / Thorakolumbale Wirbelfrakturen nach konservativer und operativer Behandlung. Abhängigkeit des Korrekturverlustes von der Höhenlokalisation.

QUESTION: This retrospective study presents results after conservative and operative treatment of thoracolumbar fractures as function of its localization. METHODOLOGY: In 2 years 70 patients with A1/A2 fracture were conservatively treated, 38 patients with A3/B/C injury were treated by internal fixtor. For evaluation 3 vertebral sections(Th5-10,Th11-L2,L3-5)were defined. Follow-up took place 1 year after implant removal or end of conservative treatment. RESULTS: The correction-loss was highest in thoracic, lowest in lumbar region. After conservative therapy,correction-loss was located to 3/4 in vertebra itself, after operative treatment especially in adjacent disc spaces. There was no general correlation to complaints. CONCLUSION: In consequence of these results A1/A2-fractures in the upper thoracic spine (15 degrees will be stabilized anteriorly, in other regions functional treated. A3-fractures of thoracic spine and thoracolumbar junction will be operated from anterior, in lower lumbar spine (>L3) from dorsal. B- and C-injuries should be instrumented with a combined dorsoventral procedure.

[Endoscopically assisted minimally invasive reconstruction of the anterior thoracolumbar spine in prone position]. / Endoskopisch assistierte Rekonstruktion der thorakolumbalen Wirbelsäule in Bauchlage.

Irrespective of an anterior open or endoscopic approach, the combined postero-anterior instrumentation of thoracolumbar fractures requires time consuming intraoperative maneuvers changing the patients position from prone to lateral.A standardised anterior endoscopically assisted approach for the segments Th4 to L4 is described, allowing the patient to remain in prone position, using a 4-5cm incision combined with a retractor system. The approach to the anterior spine in prone position is feasible by using a self holding retractor system for the region from Th4 to L4. Time of anaesthesia for the one stage combined procedure can be reduced by about 40 min, when changing the position of the patient is no longer necessary. The minimal incision in combination with the retractor system allows mainly the use of conventional instruments and implants, which provides reasonable lower costs. The advantages of the open and the endoscopical technique are combined. The main advantage of the prone position is the opportunity to access the anterior and posterior spine simultaneously, which is extremely helpful in reduction maneuvers.