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Probl Radiac Med Radiobiol ; (18): 144-55, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-25191719

RESUMEN

UNLABELLED: The objective of this study was to investigate the thyroid cancer incidence in a whole territory of Ukraine and to clear up its age and gender patterns depending on average regional (oblast) thyroid doses from radioactive iodine due to the Chornobyl accident. MATERIALS AND METHODS. On the basis of average accumulated thyroid doses from radioactive iodine the geographical regions of Ukraine with low and high average thyroid doses were identified for a comparative analysis performance. Methods of descriptive epidemiology were used. RESULTS: The level and dynamics of thyroid cancer incidence were analyzed in different gender and age groups (both for attained age and age at the moment of the Chornobyl accident). Results of this study confirmed the radiation excess of thyroid cancer in individuals who were children and adolescents in 1986. Some excess was observed in elder age groups too. Especial situation was observed in female age group 40-49 at the moment of the Chornobyl accident i.e. the age-specific thyroid cancer incidence rates were significantly higher in "high exposure" regions comparing with "low exposure" ones during all years of observation within 1989-2009. CONCLUSIONS: A probable radiation excess of thyroid cancer was suggested not only in children and adolescents but also in adult age groups. In elder age groups this excess was less expressed and manifested after a longer period of time. The origin of the phenomenon in female age group of 40-49 is unclear now. Hypothesis of combined effect of radiation and natural changing of hormonal status in this age should be checked in the future studies.


Asunto(s)
Accidente Nuclear de Chernóbil , Radioisótopos de Yodo/efectos adversos , Neoplasias Inducidas por Radiación/epidemiología , Dosis de Radiación , Contaminantes Radiactivos/efectos adversos , Neoplasias de la Tiroides , Adulto , Factores de Edad , Femenino , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Cintigrafía , Factores Sexuales , Glándula Tiroides/diagnóstico por imagen , Neoplasias de la Tiroides/epidemiología , Neoplasias de la Tiroides/etiología , Ucrania/epidemiología
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