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5.
Clin. transl. oncol. (Print) ; 23(3): 434-449, mar. 2021. ilus
Artículo en Inglés | IBECS | ID: ibc-220879

RESUMEN

The implementation of immunotherapy has radically changed the treatment of oncological patients. Currently, immunotherapy is indicated in the treatment of patients with head and neck tumors, melanoma, lung cancer, bladder tumors, colon cancer, cervical cancer, breast cancer, Merkel cell carcinoma, liver cancer, leukemia and lymphomas. However, its efficacy is restricted to a limited number of cases. The challenge is, therefore, to identify which subset of patients would benefit from immunotherapy. To this end, the establishment of immunotherapy response criteria and predictive and prognostic biomarkers is of paramount interest. In this report, a group of experts of the Spanish Society of Medical Oncology (SEOM), the Spanish Society of Medical Radiology (SERAM), and Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM) provide an up-to-date review and a consensus guide on these issues (AU)


Asunto(s)
Humanos , Antineoplásicos Inmunológicos , Neoplasias/terapia , Consenso , España , Sociedades Médicas , Progresión de la Enfermedad , Criterios de Evaluación de Respuesta en Tumores Sólidos , Neoplasias/diagnóstico por imagen , Neoplasias/inmunología
6.
Clin Transl Oncol ; 23(3): 434-449, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-32623581

RESUMEN

The implementation of immunotherapy has radically changed the treatment of oncological patients. Currently, immunotherapy is indicated in the treatment of patients with head and neck tumors, melanoma, lung cancer, bladder tumors, colon cancer, cervical cancer, breast cancer, Merkel cell carcinoma, liver cancer, leukemia and lymphomas. However, its efficacy is restricted to a limited number of cases. The challenge is, therefore, to identify which subset of patients would benefit from immunotherapy. To this end, the establishment of immunotherapy response criteria and predictive and prognostic biomarkers is of paramount interest. In this report, a group of experts of the Spanish Society of Medical Oncology (SEOM), the Spanish Society of Medical Radiology (SERAM), and Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM) provide an up-to-date review and a consensus guide on these issues.


Asunto(s)
Consenso , Inmunoterapia/métodos , Neoplasias/terapia , Sociedades Médicas , Progresión de la Enfermedad , Humanos , Inhibidores de Puntos de Control Inmunológico/uso terapéutico , Inmunoterapia/efectos adversos , Oncología Médica , Neoplasias/diagnóstico por imagen , Neoplasias/inmunología , Medicina Nuclear , Radiología , Criterios de Evaluación de Respuesta en Tumores Sólidos , España , Resultado del Tratamiento
15.
Arch Soc Esp Oftalmol ; 78(4): 227-30, 2003 Apr.
Artículo en Español | MEDLINE | ID: mdl-12743849

RESUMEN

CASE REPORT: We report the case of a 44-year-old woman, with a history of cigarette smoking (60 per day) and hyperthyroidism. She presented a bilateral ocular ischemic syndrome, and a bilateral occlusive carotid artery disease which showed reverse ophthalmic artery flow that resulted in a steal phenomenon, characterized by a shunt to the low resistance intracranial circuits and reduction of blood flow to the eyes. DISCUSSION: Young patients with severe bilateral occlusive carotid artery disease may be at greater risk of developing ocular ischemic syndrome, while this reverse flow decreases the patient's risk of stroke and death.


Asunto(s)
Arteria Carótida Interna/fisiopatología , Estenosis Carotídea/fisiopatología , Circulación Colateral , Isquemia/fisiopatología , Arteria Oftálmica/fisiopatología , Adulto , Velocidad del Flujo Sanguíneo , Arteria Carótida Interna/diagnóstico por imagen , Estenosis Carotídea/diagnóstico por imagen , Femenino , Hemodinámica , Humanos , Radiografía , Arteria Retiniana/fisiopatología , Fumar/efectos adversos , Agudeza Visual
16.
Arch. Soc. Esp. Oftalmol ; 78(4): 227-230, abr. 2003.
Artículo en Es | IBECS | ID: ibc-22636

RESUMEN

Caso clínico: Describimos el caso de una mujer de 44 años, fumadora de 60 cig./día y con antecedentes de hipertiroidismo. Presentó un síndrome de isquemia ocular en ambos ojos (AO) por oclusión de carótidas internas que originó un flujo retrógrado en ambas arterias oftálmicas, produciendo un fenómeno de robo caracterizado por un shunt a los circuitos intracraneales de baja resistencia y una reducción en el aporte sanguíneo a los ojos. Discusión: Los pacientes jóvenes con obstrucción carotídea bilateral severa tienen mayor riesgo de desarrollar un síndrome de isquemia ocular, mientras este flujo retrógrado parece reducir su riesgo de infarto cerebral o muerte (AU)


Case report: We report the case of a 44-year-old woman, with a history of cigarette smoking (60 per day) and hyperthyroidism. She presented a bilateral ocular ischemic syndrome, and a bilateral occlusive carotid artery disease which showed reverse ophthalmic artery flow that resulted in a steal phenomenon, characterized by a shunt to the low resistance intracranial circuits and reduction of blood flow to the eyes. Discussion: Young patients with severe bilateral occlusive carotid artery disease may be at greater risk of developing ocular ischemic syndrome, while this reverse flow decreases the patient’s risk of stroke and death (AU)


Asunto(s)
Adulto , Femenino , Humanos , Circulación Colateral , Tabaquismo , Estenosis Carotídea , Arteria Oftálmica , Arteria Retiniana , Velocidad del Flujo Sanguíneo , Arteria Carótida Interna , Isquemia , Hemodinámica , Agudeza Visual
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