Sociodemographic backgrounds and career decisions of Australian and New Zealand dental students.

This article describes the sociodemographic and career selection characteristics of dental students in Australia and New Zealand. A total of 672 dental students participated in the study. The survey covered age, language proficiency, type of school attended, place of residence, parental occupation, and level of education. The respondents had an average age of twenty-two years, with a range of eighteen to fifty. Fifty-six percent of respondents were female, and approximately half had completed secondary education in private schools with 44.3 percent having finished in public schools. The majority of students lived with their parents, with only a few respondents reporting a rural home address (6.8 percent). The majority of students (65.3 percent) had placed dentistry as their first career choice and had most likely made the decision after leaving high school or near the end of high school (81.4 percent), with self-motivation being the major influence on their decision. This study provides a description of the sociodemographic profile of Australian and New Zealand dental students and provides a better understanding of career decision issues. It also highlights areas for further investigation and management by educational institutions and public policy.

Genetic and environmental influences on dentofacial structures and oral health: studies of Australian twins and their families.

Our studies of the teeth and faces of Australian twins commenced at the School of Dentistry, The University of Adelaide in the early 1980s. There are now over 900 pairs of twins enrolled in our continuing investigations, together with 1200 relatives. There are 3 main cohorts of participants. The first cohort comprises around 300 pairs of teenage twins for whom various records have been collected, including dental casts, facial photographs, finger and palm prints and information on laterality, including handedness. The second cohort comprises around 300 pairs of twins who have been examined at 3 stages of dental development from approximately 4 years of age to about 14 years: at primary, mixed, and permanent dentition (excluding 3rd molars) stages. The most recent study of tooth emergence and oral health, for which we are currently recruiting twins, will provide a third cohort of around 500 twin pairs aged from around birth to 3 to 4 years of age. Our broad aim in these studies has been to improve our understanding of how genetic and environmental factors contribute to variation in dental and facial features, and to oral health. We have also used our data to investigate aspects of the determination of laterality, particularly the fascinating phenomenon of mirror imaging. We plan to maximize the use of the longitudinal data and DNA we have collected, and continue to collect, by performing genome-wide scans for putative genetic linkage peaks for a range of dental features, and then to test for association between a series of likely candidate genes and our phenotypes.

Cultural consistency in Australian dental students from two different ethnic backgrounds.

The objective of this study was to examine the value orientations of dental students from different ethnic backgrounds studying in Australian dental schools. A ninety-eight-item questionnaire was used to collect the data, including fifteen subscales developed consistent with the Kluckhohn and Strodtbeck value orientation model. To compare the value orientation structure and to determine if any ethnic differences existed, a multivariate analysis of variance called profile analysis was performed on the fifteen value subscales. Of the 401 participants, 30.2 percent were Anglo-Australian and 44.9 percent were Asian. The remainder (24.9 percent) were "Other-background residents" or "Other-international students." This article presents data from Asian (n=184) and Anglo-Australian (n=124) background respondents. Mean age was 21.7 years (s.e. 0.35 years) among Anglo-Australian and 20.8 years (s.e. 0.17 years) among Asians. Asians born overseas represented 70.7 percent (n=130) of this group. Of Australia-born Asians (n=54), 90.6 percent were first-generation Australians. When comparing their value profile, we found a significant association between ethnicity and value orientation profile scores (p<0.05). Despite the significant overall result, the strength of the association (eta(2)=0.007) indicated that this effect was trivial relative to the unexplained variance in value orientation. The findings suggest that, behind an apparent ethnic diversity, a single distinctive value profile might exist to which the majority of dental students subscribe.

Role of complement C5 and T lymphocytes in pathogenesis of disseminated and mucosal candidiasis in susceptible DBA/2 mice.

The aims of the study were to compare the pathogenesis of Candida albicans infection in various organs and anatomical regions of C5-deficient (DBA/2) and C5-sufficient (BALB/c) mice, and to evaluate the importance of complement C5 and T lymphocytes as factors that determine host susceptibility or resistance. The kidneys of DBA/2 mice showed higher colonisation and more severe tissue damage than those of BALB/c, but infection at other sites, including oral and vaginal mucosa, was generally similar in the two strains. Passive transfer of C5-sufficient serum into DBA/2 mice decreased the fungal burden in the kidney, and prolonged survival of the reconstituted animals. Depletion of CD4(+) and/or CD8(+) cells did not exacerbate either systemic or mucosal infection when compared to controls, and passive transfer of splenocytes from infected donors caused only a small and transient reduction in numbers of yeasts recovered from the kidney of sub-lethally infected recipients. It is concluded that the acute susceptibility of the kidneys in this mouse strain is due to C5 deficiency expressed on a susceptible genetic background. T lymphocytes, however, appear to have minimal influence on recovery from systemic infection with this isolate of C. albicans.