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1.
JMIR Res Protoc ; 6(4): e62, 2017 Apr 20.
Artículo en Inglés | MEDLINE | ID: mdl-28428158

RESUMEN

BACKGROUND: Oral chemotherapy is increasingly used in place of traditional intravenous chemotherapy to treat patients with cancer. While oral chemotherapy includes benefits such as ease of administration, convenience, and minimization of invasive infusions, patients receive less oversight, support, and symptom monitoring from clinicians. Additionally, adherence is a well-documented challenge for patients with cancer prescribed oral chemotherapy regimens. With the ever-growing presence of smartphones and potential for efficacious behavioral intervention technology, we created a mobile health intervention for medication and symptom management. OBJECTIVE: The objective of this study was to develop and evaluate the usability and acceptability of a smartphone app to support adherence to oral chemotherapy and symptom management in patients with cancer. METHODS: We used a 5-step development model to create a comprehensive mobile app with theoretically informed content. The research and technical development team worked together to develop and iteratively test the app. In addition to the research team, key stakeholders including patients and family members, oncology clinicians, health care representatives, and practice administrators contributed to the content refinement of the intervention. Patient and family members also participated in alpha and beta testing of the final prototype to assess usability and acceptability before we began the randomized controlled trial. RESULTS: We incorporated app components based on the stakeholder feedback we received in focus groups and alpha and beta testing. App components included medication reminders, self-reporting of medication adherence and symptoms, an education library including nutritional information, Fitbit integration, social networking resources, and individually tailored symptom management feedback. We are conducting a randomized controlled trial to determine the effectiveness of the app in improving adherence to oral chemotherapy, quality of life, and burden of symptoms and side effects. At every stage in this trial, we are engaging stakeholders to solicit feedback on our progress and next steps. CONCLUSIONS: To our knowledge, we are the first to describe the development of an app designed for people taking oral chemotherapy. The app addresses many concerns with oral chemotherapy, such as medication adherence and symptom management. Soliciting feedback from stakeholders with broad perspectives and expertise ensured that the app was acceptable and potentially beneficial for patients, caregivers, and clinicians. In our development process, we instantiated 7 of the 8 best practices proposed in a recent review of mobile health app development. Our process demonstrated the importance of effective communication between research groups and technical teams, as well as meticulous planning of technical specifications before development begins. Future efforts should consider incorporating other proven strategies in software, such as gamification, to bolster the impact of mobile health apps. Forthcoming results from our randomized controlled trial will provide key data on the effectiveness of this app in improving medication adherence and symptom management. TRIAL REGISTRATION: ClinicalTrials.gov NCT02157519; https://clinicaltrials.gov/ct2/show/NCT02157519 (Archived by WebCite at http://www.webcitation.org/6prj3xfKA).

2.
Salud ment ; 37(5): 415-422, sep.-oct. 2014. tab
Artículo en Español | LILACS-Express | LILACS | ID: lil-744133

RESUMEN

La depresión es uno de los problemas emocionales más frecuentes en pacientes con cáncer terminal. Debido a la evolución de la enfermedad, varios síntomas físicos presentes en los pacientes se pueden yuxtaponer y confundir con los síntomas que permiten identificar de manera taxonómica la depresión, lo cual dificulta la evaluación del problema. El objetivo de este artículo es realizar una revisión de los principales instrumentos utilizados para evaluar la depresión en pacientes con cáncer terminal, junto con sus implicaciones en el contexto mexicano. Con base en la información recabada se puede decir que es más pertinente realizar una evaluación de la depresión enfocada en los aspectos emocionales que en los somáticos. Actualmente existe una gran cantidad de instrumentos para evaluar la depresión que dan mayor énfasis a los aspectos de la anhedonia y las emociones que a los aspectos somáticos de la depresión. En México existe un enorme rezago en el desarrollo de instrumentos que permitan identificar estos síntomas. Se concluye señalando instrumentos alternativos para evaluar la depresión en pacientes con cáncer terminal, estos instrumentos podrían ser evaluados y considerados en un futuro en el contexto de la medicina paliativa.


Depression is one of the most common emotional problems in palliative patients. Due to the advanced nature of the disease, several physical symptoms presented by patients overlap with symptoms of depression, making it difficult to evaluate and diagnose the problem. The aim of this paper was to conduct a narrative review of the main instruments used to assess depression when it is present in palliative patients, with a special consideration of the Mexican context. Based on the available data and the scholarly literature, it is more appropriate to conduct an assessment of depression focused on emotional aspects than somatics aspects in palliative patients. Internationally, a number of depression assessments place greater emphasis on anhedonia and emotions, such as hopelessness, than on somatic aspects of depression. In Mexico, a considerable gap remains in the development of instruments to identify depression in the palliative setting. Finally, we describe alternative assessments of depression, which could be evaluated and considered in the future in the palliative care setting.

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