[New data on the spread of P-41-positive strains of the rabies virus in arctic and extra-arctic regions]. / Novye dannye o rasprostranenii P-41 polozhitel'nykh shtammov rabicheskogo virusa v arkticheskom i vnearkticheskom regionakh.

271 strains of rabies virus, isolated in different regions of the former USSR, were studied with the use of monoclonal antibodies P-41 (Germany). All strains isolated in the arctic regions, as well as some of the strains isolated in nonarctic regions situated 300-1700 km south of the polar circle (the Baltic countries, Central Yakutia, the eastern part of the Transbaikal region), gave positive reaction with these antibodies. Cases of hydrophobia caused by virus with the 41 (+) marker were described. Information on the spread such strains in other parts of the world is presented.

[Rabies prognosis in western Siberia and the regulatory factors of the epizootic process]. / Prognozirovanie beshenstva v Zapadnoi Sibiri i reguliatornye faktory épizooticheskogo protsessa.

In this article the regulatory factors of the epizootic process are considered and the spatial-temporal prognostication of rabies infection in the region is proposed on the basis of data on rabies morbidity among animals, the purchase of skins of carnivorous animals for 20-25 years, virological experiments on wild animals, calculation of the number of carnivores and small mammals, as meteorological observations. The study has shown that a variety of animal species serving as hosts for the virus and its population differences contribute to the stable existence of the infection. Rabies morbidity has been found to be positively linked with its preceding level, the number of wild animals, the height and hardness of the snow cover and negatively with the number of small mammals.

[The antigenic characteristics of field strains of the rabies virus from different districts of the USSR studied using antinucleocapsid monoclonal antibodies]. / Antigennaia kharakteristika polevykh shtammov virusa beshenstva iz razlichnykh raionov SSSR s pomoshch'iu antinukleokapsidnykh monoklonal'nykh antitel.

98 rabies virus strains isolated from different species of wild and domestic animals have been studied by means of 36 monoclonal antibodies obtained from the Wistar Institute (USA) and 3--of the Federal Research Center on Viral Diseases of Animals (FRG). The antigenic variants determined in this study have been analyzed in comparison with the data obtained in other regions of the world, thus establishing the spread of these variants and their relationship with different species of animals.

[Abortive and recurrent rabies in dogs intracerebrally infected with the rabies street virus]. / Abortivnoe i vozvratnoe beshenstvo u sobak, zarazhennykh v mozg ulichnym virusom beshenstva.

In the experiments on dogs inoculated intracerebrally with the "paralytic rabies" variant of the "Yak" strain of street rabies virus we observed spontaneous recovery of 1 out of 5 sick animals. Rabies in this dog was verified by three isolations of the virus from the saliva during the disease and by an increase of antibody titres in the time course of to 6776. In another experiment, among 7 dogs developing rabies after intracerebral inoculation with the "convulsive rabies" variant of the virus one animal showed recurrent form of rabies. The diagnosis of rabies was confirmed by isolation of the virus from the saliva in primary disease as well as by virus isolation from the salivary glands and the brain of the dog dying with recurrent rabies.

[Biological properties of variants of the rabies street virus]. / Izuchenie biologicheskikh svoistv variantov ulichnogo virusa beshenstva.

Experiments in dogs inoculated intracerebrally with biological variants of paralytic (PRV) and convulsive (CRV) rabies virus isolated from the Yak strain population of street rabies virus demonstrated distinct differences in the biological properties of the variants PRV induced in dogs paralytic rabies with a short incubation period (average 6.4 days) and CRV induced an atypical convulsive form characterized by attacks of tonic convulsions of the body, legs, and head twitching, and a longer incubation period (18.5 and 9.6 days, respectively). This explains a wide variability of the biological properties of street rabies virus strains.

[Results of a study of natural foci of rabies and evaluation of the risk of hydrophobia in new construction areas of Eastern Siberia and the Far East]. / Rezul'taty kompleksnogo izucheniia prirodnykh ochagov beshenstva i otsenka riska zabolevaniia gidrofobiei v raionakh novostroek Vostochnoi Sibiri i Dal'nego Vostoka.

The tension of the rabies epidemiological situation in the regions of new constructions in Siberia and the Far East was the result of a wide spread of the infection foci and a great number of domestic animals affected by the disease. All over the territory the main-source of the infective agent for humans are dogs, and only in a few cases wild animals. In the mountainous and steppe regions of the south-eastern part of the Transbaikal territory a natural focus of rabies has been revealed. A scheme for dividing the territory into rabies epidemiological regions has been developed on the basis of studying the factors contributing to the dynamics of the epidemic and epizootic processes, as well as the epizootic situation (in the Chita and Amur regions used as an example).