Promoting Healthy Aging: Insights on Brain and Physiological Health - A Special Issue.

This special issue focuses on healthy aging and neuroprotection, particularly in the context of brain and physiological health during normal aging and Alzheimer's disease. It highlights the importance of physical activity, nutrition, and stress management in promoting healthy aging and preventing neurodegenerative diseases. The issue explores molecular pathways, genetic factors, and lifestyle interventions that support brain and physiological health in aging populations. Overall, the findings presented in this special issue underscore the importance of healthy lifestyles in promoting brain and physiological health during the aging process.

Is Dance Closer to Physical Activity or Spirituality? A Philosophical Exploration.

Dancing is inevitably associated with kinesthetics of the body, including movements, gestures, poses, jumps, turnings, transferring body weight, etcetera. Thus, dance is a manifestation of an amateur or the skilled behavior of a fully trained athletic performance. At the same time, dance is accompanied by emotions as an effect of expression, narration of choreography. Dance is also pre-planned and designed to produce numerous styles and techniques. It is a unique type of improvisation. However, in certain situations, styles and techniques that will be discussed below, the dancing body can bring the dancer closer to his/her emotionality and even spirituality. Thus, the aim of this philosophical exploration is to analyze the impact of spirituality on dance performance.

Neuromuscular Fatigue Responses of Endurance- and Strength-Trained Athletes during Incremental Cycling Exercise.

This study explored the development of neuromuscular fatigue responses during progressive cycling exercise. The sample comprised 32 participants aged 22.0 ± 0.54 years who were assigned into three groups: endurance-trained group (END, triathletes, n = 10), strength-trained group (STR, bodybuilders, n = 10) and control group (CG, recreationally active students, n = 12). The incremental cycling exercise was performed using a progressive protocol starting with a 3 min resting measurement and then 50 W workload with subsequent constant increments of 50 W every 3 min until 200 W. Surface electromyography (SEMG) of rectus femoris muscles was recorded during the final 30 s of each of the four workloads. During the final 15 s of each workload, participants rated their overall perception of effort using the 20-point rating of the perceived exertion (RPE) scale. Post hoc Tukey's HSD testing showed significant differences between the END and STR groups in median frequency and mean power frequency across all workloads (p < 0.001 and p < 0.01, respectively). Athletes from the END group had significantly lower electromyogram amplitude responses than those from the STR (p = 0.0093) and CG groups (p = 0.0006). Increasing RPE points from 50 to 200 W were significantly higher in the STR than in the END group (p < 0.001). In conclusion, there is a significant variation in the neuromuscular fatigue profiles between athletes with different training backgrounds when a cycling exercise is applied. The approximately linear trends of the SEMG and RPE values of both groups of athletes with increasing workload support the increased skeletal muscle recruitment with perceived exertion or fatiguing effect.

Sex Differences in Anthropometric and Physiological Profiles of Hungarian Rowers of Different Ages.

The aim of this study was to determine sexual differentiation in the anthropometric and physiological characteristics of Hungarian rowers in different age categories. These characteristics were measured for 15-16-year-old juniors (55 men and 36 women), 17-18-year-old older juniors (52 men and 26 women), and 19-22-year-old seniors (23 men and 8 women). The degree of sexual dimorphism was expressed in units of measurement as percentages and the dimorphism index. In all age categories, females had significantly higher body fat indices. Body fat percentage was determined by electrical impedance and by the Parízková formula, BMI, and skinfold thicknesses. Males had significantly higher body mass, body height, skeletal muscle mass, sitting height, arm span, lower limb length, and body surface area. Males also scored significantly higher values for the following physiological characteristics: peak power, relative peak power, ErVO2max, jump height, speed max, force max, and relative maximal power. Analysis of anthropometric and physiological characteristics in Hungarian rowers revealed that sexual dimorphism tended to increase with age, regardless of whether it was expressed in units of measurement, percentages, or dimorphism index values. The age-related increase in the sexual dimorphism of Hungarian rowers suggests that training methods should be carefully selected to accommodate the needs of various age and gender groups.

Acute Cardiorespiratory and Metabolic Responses to Incremental Cycling Exercise in Endurance- and Strength-Trained Athletes.

The purpose of this study was to examine the acute effects of a progressive submaximal cycling exercise on selected cardiorespiratory and metabolic variables in endurance and strength trained athletes. The sample comprised 32 participants aged 22.0 ± 0.54 years who were assigned into three groups: an endurance trained group (END, triathletes, n = 10), a strength trained group (STR, bodybuilders, n = 10), and a control group (CON, recreationally active students, n = 12). The incremental cycling exercise was performed using a progressive protocol starting with a 3 min resting measurement and then a 50 W workload with subsequent constant increments of 50 W every 3 min until 200 W. The following cardiometabolic variables were evaluated: heart rate (HR), oxygen uptake (VO2), carbon dioxide production (VCO2), respiratory exchange ratio (RER), systolic and diastolic blood pressure (SBP and DBP), and blood lactate (BLa−). We found the between-group differences in metabolic variables (the average RER and BLa−) were statistically significant (Tukey's HSD test: CON vs. STR, p < 0.01 and p < 0.05, respectively; CON vs. END, p < 0.001; END vs. STR, p < 0.001). RER and BLa− differences in all groups depended on the workload level (G-G-epsilon = 0.438; p < 0.004 and G-G-epsilon = 0.400; p < 0.001, respectively). There were no significant differences in cardiorespiratory variables between endurance- and strength-trained groups. In conclusion, this study demonstrated that acute cardiorespiratory responses at each of the four submaximal workloads were comparable in endurance- compared to strength-trained athletes, but significantly different compared to recreationally active men. However, there were significant differences in the metabolic responses of RER and BLa−. Based on our findings we recommend that endurance-trained athletes follow a concurrent training program, combined strength and endurance training, to improve neuromuscular parameters and thus optimize their economy of movement and endurance-specific muscle power capacity.

Physiological Response to Thermal Stress in Obese vs. Non-Obese Physically Inactive Men.

The effects of thermal stress on the physiological parameters of obese subjects remain insufficiently researched. The objective of this study was to determine the influence of sauna bathing on the physiological parameters of obese and non-obese physically inactive men. Sixty volunteers aged 18−24 years (20.85 ± 1.46) were divided into two groups (group I­normal body mass, group II­class 1 obesity) for a comparative analysis. Somatic features and body composition were determined before sauna, and blood pressure was measured before and after sauna. Physiological parameters were monitored before and during the sauna session. The average values of body mass, body mass index, body surface area, and weight-to-height ratio were significantly higher (p < 0.001) in obese men (by 28.39 kg, 8.7 kg/m2, 0.34 m2, and 0.13, respectively) than in the normal weight group. Similar observations were made in an analysis of the remaining body composition parameters. The values of physiological parameters (heart rate, systolic and diastolic blood pressure, energy expenditure, oxygen uptake, excess post-exercise oxygen consumption, respiratory rate) were significantly (p < 0.001) higher in obese subjects. However, the observed physiological changes were within the expected norm; therefore, a 10 min sauna session is safe for young men regardless of their body fat levels.

Protective Effects of Exercise Become Especially Important for the Aging Immune System in The Covid-19 Era.

Aging is a complex, multietiological process and a major risk factor for most non-genetic, chronic diseases including geriatric syndromes that negatively affect healthspan and longevity. In the scenario of "healthy or good aging", especially during the COVID-19 era, the proper implementation of exercise as "adjuvant" or "polypill" to improve disease-related symptoms and comorbidities in the general population is a top priority. However, there is still a gap concerning studies analyzing influence of exercise training to immune system in older people. Therefore, the aim of this review is to provide a brief summary of well-established findings in exercise immunology and immunogerontology, but with a focus on the main exercise-induced mechanisms associated with aging of the immune system (immunosenescence). The scientific data strongly supports the notion that regular exercise as a low-cost and non-pharmacological treatment approach, when adjusted on an individual basis in elderly, induce multiple rejuvenating mechanisms: (1) affects the telomere-length dynamics (a "telo-protective" effect), (2) promote short- and long-term anti-inflammatory effects (via e.g., triggering the anti-inflammatory phenotype), 3) stimulates the adaptive immune system (e.g., helps to offset diminished adaptive responses) and in parallel inhibits the accelerated immunosenescence process, (4) increases post-vaccination immune responses, and (5) possibly extends both healthspan and lifespan.

Effects of Intensity Modulated Total-Body Circuit Training Combined with Soccer Training on Physical Fitness in Prepubertal Boys after a 6-Month Intervention.

The purpose of this study was to examine the effects of a 6-month high- or moderate-intensity total-body circuit training (CT) program on physical fitness in prepubertal soccer players. Sixty-seven prepubertal boys with a mean age of 11.2 ± 0.7 years completed the study. Participants from a soccer academy were randomly assigned either to a high-intensity CT group (HCT, n = 22) or a moderate-intensity CT group (MCT, n = 24). A control group (CON, n = 21) comprised age-matched individuals who were not involved in any regular training regime. CT protocols were included in the experimental group's training sessions 3 times per week over 24 weeks as part of their usual weekly training regime. Based on the HR zone method, CT protocols included high- or moderate-intensity (85-95% HRmax or 75-85% HRmax) series of 3 different sets of upper- and lower-body strength exercises with articular and muscular mobilization, all culminated with 40-m sprints. Physical fitness was evaluated by the Eurofit test which included the flamingo balance (FLB), plate tapping (PLT), sit-and-reach (SAR), standing broad jump (SBJ), handgrip (HG), sit-ups (SUP), bent arm hang (BAH), 10×5 m shuttle run (SHR), and the Physical Working Capacity test (PWC170). The two-way ANOVA indicated group×time interaction effects for 5 components: the largest was for the SBJ (F2,63 = 42.895, p < 0.001, η2 = 0.577), and the lowest for the SHR (F2,63 = 5.006, p < 0.01, η2 = 0.137) indicating better improvements in the HCT compared to the MCT group. Furthermore, for HCT and MCT groups the highest pre- to post-intervention percentage changes were for the FLB and the SAR, while in the CON group the changes of all physical fitness components were not significant (p < 0.05). In conclusion, the intensity-controlled total-body CT protocol incorporated into a standard soccer training program is effective for enhancement in physical fitness performance in prepubertal soccer players.

Exercise in Aging: Be Balanced.

The beneficial effects of exercise are recognized for preventing physical and cognitive decline during the aging process. However, there is still a gap concerning recommended intensity, volume, frequency and mode of exercise especially for older people. The aim of this study was to investigate an appropriate type of physical activity (PA) model for healthy aging. A commentary of the influence of PA and exercise on healthy aging through an online search of the databases Web of Science, PubMed and Google Scholar. Two living groups can be considered as potential references: modern hunter-gatherer small-scale population and master athletes. Greater physical activity is proposed for healthy aging than that recommended by WHO. Additionally, mindfulness meditation techniques during exercise are recommended especially for persons practicing long-duration exercises. Complex and compound exercise and workouts should include challenging exercises adjusted and balanced to provide clients, especially older people, with noticeable changes and progress.

Pro-Healthy Diet Properties and Its Determinants among Aging Masters Athletes.

Qualitative dietary assessments are not common in aging athletes. Therefore, this study aimed to evaluate diet quality and its determinants among aging masters athletes. Eighty-six participants of the 8th World Masters Indoor Athletics Championships were enrolled in the study (age range 36-65 years). Three subgroups were distinguished to represent countries with different eating habits. Body composition was measured by bioelectrical impedance. Eating habits and diet quality were assessed using the Dietary Habits and Nutrition Beliefs Questionnaire (KomPAN®, Warszawa, Poland), and the Pro-healthy Diet Index (pHDI-10). Dietary quality determinants were identified by a multiple regression model conducted for each subgroup separately (Great Britain, France, and Poland). The results showed that none of the subgroups adhered to the reference intake of products with beneficial health outcomes. This was particularly noticeable in the insufficient consumption of whole grain products, dairy, and fish. The fish and vegetables consumption frequency significantly differentiated the eating habits of the studied groups. Diet quality determinants varied depending on the group. However, in each of them, fruit consumption was one of the components of a good-quality diet. The obtained results can be used by institutions providing health education among the elderly to develop an appropriate strategy aimed at changing inappropriate eating habits.

Body adaptation to Dance: A Gerontological Perspective.

A number of studies have investigated the effectiveness of dance in older adults in the context of healthy aging. Analysing results across studies is important to understand whether dance in older adults is an effective adjunctive intervention for the healthy aging. To summarize the current research results about the effectiveness of dance in older adults in the context of healthy aging, and to identify key areas for future research. The search was conducted in Web of Science, PubMed and Google Scholar databases, using the following search string and Boolean logic ('AND', 'OR') locating studies published between database inception and September 2018: Dance OR contemporary dance OR ballroom dance OR Latin dance OR standard dance OR hip-hop dance OR tango AND Cardiovascular OR circulation AND Emotion OR well-being OR blood pressure OR disease OR thrombosis OR vascular OR glucose OR blood OR cardiac OR mental OR heart rate. Two reviewers independently extracted studies data. Eight suitable publications were included. The results showed that dance promote improvements in cognitive parameters when compared to other types of exercise or no-exercise. Significant effects were found on some physiological parameters, even after a short intervention period. Dance proved to be able to assist older adults in the context of healthy aging. The improvements in the cognitive, physiological and motor control parameters are very relevant for this population, due to the impact in a better quality of life.

Hepatic glycogen storage diseases: pathogenesis, clinical symptoms and therapeutic management.

Glycogen storage diseases (GSDs) are genetically determined metabolic diseases that cause disorders of glycogen metabolism in the body. Due to the enzymatic defect at some stage of glycogenolysis/glycogenesis, excess glycogen or its pathologic forms are stored in the body tissues. The first symptoms of the disease usually appear during the first months of life and are thus the domain of pediatricians. Due to the fairly wide access of the authors to unpublished materials and research, as well as direct contact with the GSD patients, the article addresses the problem of actual diagnostic procedures for patients with the suspected diseases. Knowledge and awareness of the problem among physicians seem insufficient, and research on the diagnosis and treatment of GSD is still ongoing, resulting in a heterogeneous GSD typology and a changing way of its diagnosis and treatment.

The Mechanism of Physical Activity-induced Amelioration of Parkinson's Disease: A Narrative Review.

Physical activity, together with its ameliorative effects on Parkinson's disease (PD) symptoms, remains a relatively unappreciated factor which may be beneficial for the treatment outcome. Contemporary evidence supports the positive effects of non-pharmacological approaches to PD symptom management, in particular the effects of the exercise on both, motor and non-motor symptoms. The aim of the study was to review the mechanisms of exercise-induced amelioration of PD symptoms. Methods: Electronic databases (PubMed, Web of Science and Google Scholar) were searched using the following key words: "Parkinson and physical activity" OR "Parkinson disease and exercise" OR "Parkinson disease and lifestyle factors" OR "Parkinson disease and longevity". A total of 97 studies which investigated PD genetics and various forms of exercise and their etiologic impact on PD were reviewed. The studies were subdivided into four topic groups: 1) genetics of PD, 2) exercise and the brain, 3) physical activity and PD, 4) mind-body interventions, and discussed accordingly. Adequate levels of physical activity are associated with higher quality of life in PD patients. Physical activity may have protective and stimulatory effects for better functional efficiency in higher-level cognitive networks. It can also improve balance and motor functions by improving muscle strength. Given the etiologic evidence of the beneficial effects of physical activity on PD, albeit tentative, a concerted effort to elucidate the processes and outcomes of physical activity on ameliorating symptoms of PD must be undertaken.

Relationships Between Measures of Functional and Isometric Lower Body Strength, Aerobic Capacity, Anaerobic Power, Sprint and Countermovement Jump Performance in Professional Soccer Players.

The purpose of this study was to assess a wide range of physiological and performance variables and investigate whether and to what extent these variables are associated with each other in soccer. Twenty-five male soccer players (25.1 ± 4.56 years; body mass, 75.2 ± 5.92 kg; body height, 180.6 ± 5.45 cm) performed: 5- and 30-m sprints (T5m and T30m, respectively), 1-repetition-maximum (1RM) half squat, maximal voluntary isometric contraction (MVIC) of the knee extensors, countermovement jump (CMJ) to obtain vertical jump height (CMJheight) and power output (CMJpower), the 10-s Wingate Anaerobic Test (WAnT) to obtain peak power (Pmax), and the 20-m multi-stage shuttle run test (MST) to evaluate aerobic capacity. 1RM, MVIC, and Pmax were normalized to body mass. Large negative correlations were found between sprint times and 1RM half back squat/BM (r = -0.510 to -0.570, r2 = 0.260-0.325, both p < 0.01) and Pmax/BM (r = -0.501, r2 = 0.251, p < 0.01). T30m most strongly and negatively correlated with CMJheight (r = -0.744, r2 = 0.554, p < 0.001). WAnT-determined Pmax showed a very large correlation between absolute Pmax and knee-extensor MVIC (r = 0.827, r2 = 0.684, p < 0.001) and large correlations between absolute Pmax and 1RM half squat (r = 0.674, r2 = 0.454, p < 0.001) and CMJpower (r = 0.579, r2 = 0.335, p < 0.01). We also identified a large inverse relationship between CMJheight and T30m (r = -0.744, r2 = 0.554, p < 0.001) and large positive correlation between CMJheight and MVIC/BM (r = 0.702, p < 0.001). The results demonstrate that elite soccer players with greater lower body strength (quantified by the MVIC of the knee extensor and the 1RM half squat) show better sprint and CMJ performance, suggesting the incorporation of soccer-specific resistance training to develop lower body musculature and therefore maximize sprinting ability. The higher correlation coefficients found between T30m and the physiological and athletic measures compared with T5m promote the use of this sprint distance when assessing performance. The use of relative measures (normalized to body mass) is advisable when comparing strength variables with sprint and CMJ performance or anaerobic power. Considering the correlations of WAnT-determined Pmax versus CMJpower, coaches should administer tests that assess jumping and linear sprint performance rather than the cycling-specific WAnT.

A Review of Exercise as Medicine in Cardiovascular Disease: Pathology and Mechanism.

BACKGROUND: Physical inactivity and resultant lower energy expenditure contribute unequivocally to cardiovascular diseases, such as coronary artery disease and stroke, which are considered major causes of disability and mortality worldwide. AIM: The aim of the study was to investigate the influence of physical activity (PA) and exercise on different aspects of health - genetics, endothelium function, blood pressure, lipid concentrations, glucose intolerance, thrombosis, and self - satisfaction. Materials and. METHODS: In this article, we conducted a narrative review of the influence PA and exercise have on the cardiovascular system, risk factors of cardiovascular diseases, searching the online databases; Web of Science, PubMed and Google Scholar, and, subsequently, discuss possible mechanisms of this action. RESULTS AND DISCUSSION: Based on our narrative review of literature, discussed the effects of PA on telomere length, nitric oxide synthesis, thrombosis risk, blood pressure, serum glucose, cholesterol and triglycerides levels, and indicated possible mechanisms by which physical training may lead to improvement in chronic cardiovascular diseases. CONCLUSION: PA is effective for the improvement of exercise tolerance, lipid concentrations, blood pressure, it may also reduce the serum glucose level and risk of thrombosis, thus should be advocated concomitant to, or in some cases instead of, traditional drug-therapy.

Socioeconomic Determinants of the Anthropometric Characteristics and Motor Abilities of Polish Male University Students: A Cross-Sectional Study Conducted in 2000-2018.

Aim: The aim of this study was to determine the relationships between socioeconomic factors, anthropometric characteristics and motor abilities of male university students. Materials and Methods: The study was conducted from 2000 to 2018 on 2691 male university students aged 19.98 ± 1.05 years, who were randomly selected from students attending obligatory physical education (PE) classes. The participants' body mass and height were measured, and students participated in 13 motor ability tests that assessed their speed/agility, flexibility, strength and endurance abilities. Multiple independent samples were compared with the Kruskal-Wallis test or the mean-ranks post-hoc test when significant differences were observed in the participants' motor abilities. Results: Factors such as the place of permanent residence, students' monthly budget, and mother's and father's educational background, significantly (p < 0.05) influenced the body mass, BMI and motor abilities of first-year university students. The participants' motor abilities (speed/agility, flexibility-partly, strength, strength endurance, and endurance) were most frequently and most significantly determined by their monthly budgets, and were least frequently and least significantly determined by their place of permanent residence. Conclusions: The students' body height, BMI and motor abilities generally increased with a rise in population in the place of permanent residence, monthly budget, and the parents' educational attainment.

Physical Activity and Alzheimer's Disease: A Narrative Review.

Although age is a dominant risk factor for Alzheimer's disease (AD), epidemiological studies have shown that physical activity may significantly decrease age-related risks for AD, and indeed mitigate the impact in existing diagnosis. The aim of this study was to perform a narrative review on the preventative, and mitigating, effects of physical activity on AD onset, including genetic factors, mechanism of action and physical activity typology. In this article, we conducted a narrative review of the influence physical activity and exercise have on AD, utilising key terms related to AD, physical activity, mechanism and prevention, searching the online databases; Web of Science, PubMed and Google Scholar, and, subsequently, discuss possible mechanisms of this action. On the basis of this review, it is evident that physical activity and exercise may be incorporated in AD, notwithstanding, a greater number of high-quality randomised controlled trials are needed, moreover, physical activity typology must be acutely considered, primarily due to a dearth of research on the efficacy of physical activity types other than aerobic.

International Standards for the 3-Minute Burpee Test: High- Intensity Motor Performance.

The aim of this study was to develop international standards for evaluating strength endurance with the use of the 3-Minute Burpee Test. The results of 3862 women (Poland - 2502, Great Britain - 500, Hungary - 412, Serbia - 448) and 5971 men (Poland - 4517, Great Britain - 500, Hungary - 451, Serbia - 503) aged 18-25 (mean age of 20.36 ± 0.94 and 20.05 ± 1.25 y, respectively) were collated between 2004 and 2018. The students' strength endurance was evaluated in the 3-Minute Burpee Test. The results were expressed on a uniform scale with the 3-sigma rule which was used to develop the T-score scale for the 3-Minute Burpee Test. Men completed 56.69 cycles/3 min and women - 48.84/3 min on average. The best male participant completed 82 burpees, and the best female participant - 73 burpees. The majority of male and female participants (66.71% and 68.18%, respectively) were characterized by average strength endurance in the 3-Minute Burpee Test (range of scores: 47-66 and 37-60 cycles/3 min, respectively). Very good strength endurance (76-85 and 72-83 cycles/3 min, respectively) was noted in the smallest percentage of male and female participants (0.52% and 0.26%, respectively). Similar studies should be carried out in other countries and in different age groups to develop objective international classification standards for variously-aged individuals.

The Heider balance and the looking-glass self: modelling dynamics of social relations.

We consider the dynamics of interpersonal relations which leads to balanced states in a fully connected network. Here this approach is applied to directed networks with asymmetric relations, and it is generalized to include self-evaluation of actors, according to the 'looking-glass self' theory. A new index of self-acceptance is proposed: the relation of an actor to him/herself is positive, if the majority of his/her positive relations to others are reciprocated. Sets of stable configurations of relations are obtained under the dynamics, where the self-evaluation of some actors is negative. Within each set all configurations have the same structure.

Correlations between Repeated Use of Dry Sauna for 4 x 10 Minutes, Physiological Parameters, Anthropometric Features, and Body Composition in Young Sedentary and Overweight Men: Health Implications.

BACKGROUND: The effect of thermal stress on the physiological parameters of young overweight and sedentary men who sporadically use the sauna remains insufficiently investigated. AIM: The aim of the study was to determine the effect of sauna bathing on the physiological parameters of young overweight, physically inactive men and to test the correlations between physiological parameters versus anthropometric features and body composition parameters. MATERIALS AND METHODS: Forty-five overweight and sedentary men aged 20.76±2.4 y were exposed to four sauna sessions of 10 minutes each (temperature: 90-91°C; relative humidity: 14-16 %) with four 5-minute cool-down breaks. Body composition was determined before sauna, and body mass and blood pressure were measured before and after sauna. Physiological parameters were monitored during four 10-minute sauna sessions. RESULTS: A significant (p<0.0001) increase in all analyzed physiological parameters was observed during four successive 10-minute sauna sessions. Heart rate, energy expenditure, blood pressure, and body mass loss were most strongly correlated with anthropometric parameters (body mass, body mass index, and body surface area) and body composition parameters (percent body fat, body fat mass, and visceral fat level). The 60-minute treatment resulted in a significant reduction in body mass (0.65 kg). CONCLUSIONS: Repeated use of Finnish sauna induces significant changes in the physiological parameters of young sedentary overweight men, and these changes are intensified during successive treatments. Deleterious cardiovascular adaptations were most prevalent in men characterized by the highest degree of obesity and the largest body size.