Sensitizing agents found in children and adolescents with recalcitrant atopic dermatitis: a cross-sectional study with a pediatric battery.

BACKGROUND: Atopic dermatitis is the most common inflammatory skin disease in childhood and has an important impact on quality of life, especially severe cases or those that are recalcitrant to treatments. Sensitization to allergens with the potential for allergic contact dermatitis is a factor associated with cases of recalcitrant atopic dermatitis. Understanding the relationship between atopic dermatitis, allergens, and allergic contact dermatitis is essential. In Brazil, there are no studies on sensitization to allergens found in patch tests with pediatric batteries in patients with atopic dermatitis. OBJECTIVES: To verify the main sensitizing agents, the prevalence of allergic contact dermatitis and the epidemiological and clinical profile of children and adolescents with atopic dermatitis. METHODS: Cross-sectional, prospective study in patients between 4 and 18 years of age, with recalcitrant atopic dermatitis, treated at the Sanitary Dermatology Outpatient Clinic (RS). All patients underwent patch tests with a battery of pediatric allergens. RESULTS: The prevalence of sensitization and allergic contact dermatitis in the evaluated patients was 37.07% (20/54) and 27.7% (15/54), respectively. The most frequent allergens were: nickel sulfate (16.7%), disperse blue (5.6%), and fragrance mix I (5.6%). Nickel was associated with the female sex (p = 0.019). STUDY LIMITATIONS: Sample size and selection, absence of a control group. CONCLUSIONS: A proportion of patients with recalcitrant atopic dermatitis may be sensitized to different allergens and may even have developed allergic contact dermatitis. Recognizing this context is important in the prevention strategy and management of the disease.

Sensitizing agents found in children and adolescents with recalcitrant atopic dermatitis: a cross-sectional study with a pediatric battery

Abstract Background Atopic dermatitis is the most common inflammatory skin disease in childhood and has an important impact on quality of life, especially severe cases or those that are recalcitrant to treatments. Sensitization to allergens with the potential for allergic contact dermatitis is a factor associated with cases of recalcitrant atopic dermatitis. Understanding the relationship between atopic dermatitis, allergens, and allergic contact dermatitis is essential. In Brazil, there are no studies on sensitization to allergens found in patch tests with pediatric batteries in patients with atopic dermatitis. Objectives To verify the main sensitizing agents, the prevalence of allergic contact dermatitis and the epidemiological and clinical profile of children and adolescents with atopic dermatitis. Methods Cross-sectional, prospective study in patients between 4 and 18 years of age, with recalcitrant atopic dermatitis, treated at the Sanitary Dermatology Outpatient Clinic (RS). All patients underwent patch tests with a battery of pediatric allergens. Results The prevalence of sensitization and allergic contact dermatitis in the evaluated patients was 37.07% (20/54) and 27.7% (15/54), respectively. The most frequent allergens were: nickel sulfate (16.7%), disperse blue (5.6%), and fragrance mix I (5.6%). Nickel was associated with the female sex (p = 0.019). Study limitations Sample size and selection, absence of a control group. Conclusions A proportion of patients with recalcitrant atopic dermatitis may be sensitized to different allergens and may even have developed allergic contact dermatitis. Recognizing this context is important in the prevention strategy and management of the disease.

A importância do pré natal odontológico e a implantação do atendimento odontológico às gestantes na UBS Morada São Luiz em Sapiranga ­ RS

Este projeto de intervenção é uma proposta para a implementação do pré natal odontológico no atendimento das gestantes usuárias da UBS Morada São Luiz, no município de Sapiranga, Rio Grande do Sul. Considerando que o Ministério da Saúde recomenda que todas as gestantes de baixo risco realizem uma avaliação odontológica por trimestre, ao observar que esse aspecto poderia ser ampliado, na perspectiva da integralidade, esse projeto foi pensando para qualificar ainda mais o atendimento de pré natal oferecido as gestantes cadastradas. A metodologia compreende sensibilizar a equipe de saúde, de forma multidisciplinar, sobre a importância dos cuidados odontológicos na assistência ao pré natal, levantar as dúvidas mais frequentes das gestantes adscritas na área, elaborar um folder educativo para ser anexado a carteira de pré natal do Ministério da Saúde o qual terá também a intenção não só de informar as gestantes, mas também de organizar e agendar as consultas odontológicas, as quais terão horários exclusivos reservados na agenda odontológica para atendimento destinado as gestantes. Espera-se com o processo de implementação do pré natal odontológico, aprimorar o conhecimento da equipe de saúde e das gestantes acerca da saúde bucal, esclarecer as principais dúvidas, organizar e gerenciar o atendimento odontológico das gestantes, para atender essa população de forma cada vez mais integral e dessa forma atingir a mais uma recomendação do Ministério da Saúde.