RESUMEN
Epilepsy is one of the most prevalent chronic disorders of childhood which can threaten child development and mental health. Among cognitive disorders, dyscalculia is one of the most important. In this study, 39 children and adolescents with idiopathic epilepsy underwent clinical and neuropsychological assessment to determine the intellectual level, math skills, reading and writing performance and neuropsychological profile. It was observed that the mathematical ability was below schooling expectations in a higher frequency than expected. There were no significant differences in mathematical performance among groups divided by number of antiepileptic drugs used, duration of disease and types and frequency of seizures. There was a positive correlation with intelligence quotient and attentional and reading level. These results suggest the existence not only of dyscalculia, but the concurrence of attentional and reading problems for the poor mathematical performance in this population.
Asunto(s)
Discalculia/fisiopatología , Epilepsia/fisiopatología , Adolescente , Brasil , Niño , Trastornos del Conocimiento/fisiopatología , Discalculia/diagnóstico , Dislexia/fisiopatología , Femenino , Humanos , Pruebas de Inteligencia , Masculino , Matemática , Pruebas Neuropsicológicas , Solución de Problemas , Valores de Referencia , Estadísticas no Paramétricas , Encuestas y CuestionariosRESUMEN
Epilepsy is one of the most prevalent chronic disorders of childhood which can threaten child development and mental health. Among cognitive disorders, dyscalculia is one of the most important. In this study, 39 children and adolescents with idiopathic epilepsy underwent clinical and neuropsychological assessment to determine the intellectual level, math skills, reading and writing performance and neuropsychological profile. It was observed that the mathematical ability was below schooling expectations in a higher frequency than expected. There were no significant differences in mathematical performance among groups divided by number of antiepileptic drugs used, duration of disease and types and frequency of seizures. There was a positive correlation with intelligence quotient and attentional and reading level. These results suggest the existence not only of dyscalculia, but the concurrence of attentional and reading problems for the poor mathematical performance in this population.
A epilepsia é uma das doenças crônicas mais comuns da infância que pode ameaçar o desenvolvimento infantil e saúde mental. Dos distúrbios cognitivos, a discalculia é um dos mais importantes. Neste estudo, 39 crianças e adolescentes com epilepsia idiopática, foram submetidos à avaliação clínica e neuropsicológica para determinar o nível intelectual, habilidade em matemática, leitura e escrita e perfil neuropsicológico. Observou-se que a habilidade em matemática ficou abaixo das expectativas de escolarização em uma frequência maior do que a esperada. Não houve diferenças significativas no desempenho matemático em relação ao número de drogas antiepilépticas utilizadas, duração da doença, tipo e frequência das crises. Houve uma correlação positiva com o quociente de inteligência e nível de atenção e leitura. Estes resultados sugerem a existência não só de discalculia, mas também a existência de problemas atencionais e de leitura que fatores causais para a dificuldade matemática apresentada nesta amostra.
Asunto(s)
Adolescente , Niño , Femenino , Humanos , Masculino , Discalculia/fisiopatología , Epilepsia/fisiopatología , Brasil , Trastornos del Conocimiento/fisiopatología , Discalculia/diagnóstico , Dislexia/fisiopatología , Pruebas de Inteligencia , Matemática , Pruebas Neuropsicológicas , Solución de Problemas , Valores de Referencia , Estadísticas no Paramétricas , Encuestas y CuestionariosRESUMEN
The aim of this study was to evaluate the hypothesis that the association between nutritional status and gender of rat pups during the early postnatal period (lactation) induces changes in glucose homeostasis and blood pressure of the pups when becoming adults. The results indicate that undernourishment during lactation is associated with gender and affects glucose homeostasis and blood pressure of female adults. In our experiments, the blood glucose level at the end of a clamping was significantly different in the undernourished females (FU) compared with the female controls (FC) (FC: 11.2 +/- 0.9 mmol/l; FU: 26.9 +/- 2.1 mmol/l; p =0.001). On the other hand, the undernourished male (MU) group, when compared with the male control (MC) group, showed constant and similar glycemia during clamp-induced hyperglycemia, despite there being a significant reduction of plasma insulin (at the end of the clamping, MC: 595 +/- 35 pmol/l and MU: 210 +/- 4 pmol/l) in this group. In addition, in contrast to the control groups and the MU group, the systolic and diastolic (d) pressures at the end of the experimental period of the FU group were significantly lower than those of the FC group (FC: 15.3 +/- 0.30 mm Hg and FU: 14.7 +/- 0.25 mm Hg, p < 0.001; FCd: 7.7 +/- 0.25 mm Hg and Fud: 6.8 +/- 0.4 mm Hg, p=0.001). Therefore, our results provide clear evidence that nutrition is associated with gender during the early postnatal period by inducing persistent changes in physiological outcomes.