[Characteristics of arrhythmia and late ventricular potentials in patients with cardiological syndrome X]. / Kharakteristika narushenii serdechnogo ritma i pozdnie potentsialy zheludochkov u bol'nykh s kardiologicheskim sindromom X.

AIM: A comparative study of late ventricular potentials (LVP) in patients with cardiological syndrome X (SX) and stenotic atherosclerosis of coronary arteries (ACA) as well as their relations with arrhythmia, cardiac contractility, lipid metabolism and morphological characteristics of the myocardium. MATERIAL AND METHODS: The examination of 52 SX and 77 ACA patients as well as 17 healthy subjects included coronaroventriculography, bicycle exercise, 24-h ECG monitoring, echocardiography, signal-averaged high-resolution (SAHR) ECG, investigation of blood lipoproteins. Endomyocardial biopsy was made in 5 ACA and 5 SX patients. RESULTS: No differences were registered between SX and ACA patients by frequency and severity of arrhythmic episodes, percentage of patients with registered LVP, quantitative parameters of SAHR ECG. Frequency of high-gradation ventricular arrhythmia episodes was significantly higher in SX and ACA patients with LVP than such patients free of LVP. SX patients had correlation between parameters of SAHR ECG, myocardial contractility and lipid metabolism. Foci of diffuse cardiosclerosis are most probable anatomic substrate of LVP. CONCLUSION: The risk of prognostically unfavourable high-gradation ventricular arrhythmia episodes in SX and ACA patients is the same. LVP may predict severe ventricular arrhythmia episodes both in SX and ACA patients.

[The effect of carbon dioxide baths and applications of low-temperature peloids on the immune function of patients with psoriatic arthritis]. / Vliianie gazovykh uglekislykh vann i applikatsii peloidov nizkikh temperatur na immunnoe sostoianie bol'nykh psoriaticheskim artritom.

A trial of dry air effervescent baths and low-temperature peloid applications was made in 109 patients with psoriatic arthritis (PA). Marked response was achieved in patients who had received combined therapy with the above two modalities. The effect presented with lower articular index, weaker skin involvement, improvement of blood picture. These positive changes correlated with normalization of immune indices. The benefit persisted for 6-9 months.

[Clinical and prognostic significance of the degree of delayed ventricular function and vegetative regulation of cardiac rhythm in myocardial infarction patients]. / Klinicheskaia i prognosticheskaia znachimost' pokazatelei zamedlennoi zheludochkovoi aktivnosti i vegetativnoi reguliatsii ritma serdtsa u bol'nykh infarktom miokarda.

Ventricular tachyarrhythmias (VT) are responsible for many sudden deaths in postmyocardial infarction (PMI) patients. The aim of the study was to investigate clinical and prognostic significance for such patients of delayed ventricular activity and vegetative regulation of cardiac rhythm. Signal-averaged ECG, mathematical analysis of cardiac rhythm with measurement of variation range, mode, index of regulatory systems tension, 24-h ECG monitoring were made in 90 patients with acute large-focal myocardial infarction (MI) on the disease day 1, 15, 40 and 365. Signal-averaged ECG registered on MI day 15 was found most informative for identifying the risk to develop VT. Combined application of diagnostic techniques brings more information than each of them alone.

[The combined use of dry-air carbon dioxide baths and applications of peloids at low temperatures in the rehabilitation of patients with psoriatic arthritis]. / Kompleksnoe ispol'zovanie sukhovozdushnykh uglekislykh vann i applikatsii peloidov nizkikh temperatur v reabilitatsii bol'nykh psoriaticheskim artritom.

Low-temperature peloids and dry effervescent baths were tried in the treatment of 106 patients with psoriatic arthritis. The response was achieved in 70% of patients. The articular index, psoriatic lesions of the skin, inflammation diminished for 6-9 months.

[Phenomenon of preoperative stress in patients with ischemic heart disease. Assessment of its clinical and prognostic significance]. / Fenomen predoperatsionnogo stressa u bol'nykh IBS. Otsenka ego klinicheskoi i prognosticheskoi znachimosti.

AIM: To assess preoperative stress in patients with ischemic heart disease (IHD) and its influence on the course of early intraoperative period. MATERIALS AND METHODS: 79 patients scheduled for aortocoronary bypass operation were studied to assess the phenomenon of preoperative psychoemotional stress (clinical characteristics, personal anxiety, humoral and vegetative regulation. RESULTS: 24 hours before operation IHD patients became anxious, coronary insufficiency and arrhythmia aggravated as shown by Holter ECG monitoring. Initial insufficiency of the antioxidant system, disturbances of the platelet-vascular hemostasis, hyperlipidemia and dyslipoproteinemia enhanced. Preoperative changes due to stress reaction affected the course of early intraoperative period. CONCLUSION: It is necessary to apply individual schemes of stress-limiting preoperative preparation in IHD patients.

[Late ventricular potentials and autonomic cardiac rhythm regulation in patients with acute myocardial infarction]. / Pozdnie zheludochkovye potentsialy i vegetativnaia reguliatsiia ritma serdtsa u bol'nykh s ostrym infarktom miokarda.

Relationship between late ventricular potentials (LVP) and vegetative regulation of cardiac rhythm was investigated in 52 patients with acute myocardial infarction. Using signal-averaged ECG and mathematical analysis of cardiac rhythm registered on infarction days 1, 15 and 40 it was found that by disease day 40 a direct correlation became more and more evident between inhibited ventricular activity and the intensity of sympathetic impacts on cardiac rhythm. Thus, the onset of ventricular arrhythmia in patients with myocardial infarction is resultant not only from the presence of arrhythmia substrate, but also from "the autonomic background".