[Safety and possible penetration of pyridoxal phosphate across the skin barrier when used epicutaneously]. / Izuchenie bezvrednosti i vozmozhnosti proniknoveniia cherez kozhnyi bar'er piridoksal'fosfata pri ego nakozhnom primenenii.

It was demonstrated in experiments on various animal species that pyridoxal phosphate had low toxicity and easily penetrated across the skin barrier without producing general toxic, irritant and allergenic effects.

[Comparative study of the vitamin activity of pyridoxal phosphate and pyridoxine used cutaneously]. / Sravnitel'noe izuchenie vitaminnoi aktivnosti piridoksal'-fosfata i piridoksina pri ikh nakozhnom primenenii.

In white rats with B6-avitaminosis, the B6-vitamin activity of pyridoxal-phosphate and of pyridoxine was studied in their epicutaneous and peroral application. It is revealed that pyridoxal-phosphate in epicutaneous application displays more activity than pyridoxine and pyridoxal-phosphate applied perorally. Pyridoxine in epicutaneous application does not reveal the B6-vitamin activity.