An Aggregated Data Integration Approach to the Web and Cloud Platforms through a Modular REST-Based OPC UA Middleware.

The Internet of Things (IoT) empowers the development of heterogeneous systems for various application domains using embedded devices and diverse data transmission protocols. Collaborative integration of these systems in the industrial domain leads to incompatibility and interoperability at different automation levels, requiring unified coordination to exchange information efficiently. The hardware specifications of these devices are resource-constrained, limiting their performance in resource allocation, data management, and remote process supervision. Hence, unlocking network capabilities with other domains such as cloud and web services is required. This study proposed a platform-independent middleware module incorporating the Open Platform Communication Unified Architecture (OPC UA) and Representational State Transfer (REST) paradigms. The object-oriented structure of this middleware allows information contextualization to address interoperability issues and offers aggregated data integration with other domains. RESTful web and cloud platforms were implemented to collect this middleware data, provide remote application support, and enable aggregated resource allocation in a database server. Several performance assessments were conducted on the developed system deployed in Raspberry Pi and Intel NUC PC, which showed acceptable platform resource utilization regarding CPU, bandwidth, and power consumption, with low service, update, and response time requirements. This integrated approach demonstrates an excellent cost-effective prospect for interoperable Machine-to-Machine (M2M) communication, enables remote process supervision, and offers aggregated bulk data management with wider domains.

Left ventricular mass and functions in normotensive offspring of hypertensive parents: an echocardiographic study.

OBJECTIVE: Published observations about cardiovascular alterations in normotensive individuals genetically predisposed to develop essential hypertension are conflicting. We tested the hypothesis that abnormalities in left ventricular mass and/or functions may be present in normotensive children of hypertensive parents. METHODS: One hundred normotensive offsprings (6 to 18 year age) of hypertensive parents (OHP) and an equal number of age- and sex-matched normotensive offsprings of normotensive parents (ONP) were studied with 2-dimensionally guided M-mode and Doppler echocardiography for left ventricular (LV) dimensions, mass, and systolic and diastolic functions. RESULTS: Both the groups had similar body mass index and blood pressure levels. LV dimensions and LV mass in OHP were higher than the corresponding values in ONP but the differences were not statistically significant. LV mass in male OHP was higher than in female OHP; LV mass was also higher when the mother rather than father was hypertensive. None of these differences were statistically significant, however. LV systolic functions were normal and identical in the two subject groups. Indices of LV diastolic function (peak early filling velocity and its deceleration time and late filling velocity) were also normal and similar in the two groups. CONCLUSION: We conclude that children with a family history of essential hypertension have modest alterations in LV mass and these alterations might have a genetic basis separate from but possibly co-inherited with the trait of essential hypertension.

Brugada syndrome.

The syndrome of right bundle branch block, ST segment elevation from VI-V3 and syncopal episodes and/or sudden death in a patient with structurally normal heart is a new entity, named Brugada syndrome in 1992. In some individuals, the presentation may be asymptomatic with only abnormal electrocardographs while in others a history of sudden death in the family and electrocardiographic criteria are observed. This disease is genetically determined caused by a defect in the myocardial sodium channel (SCN5A). Sudden death in individuals with this syndrome can only be prevented by implanting a cardioverter-defibrillator.