1.
Science
; 191(4227): 578-9, 1976 Feb 13.
Artículo
en Inglés
| MEDLINE
| ID: mdl-943127
RESUMEN
Behavioral deficits in adult rats exposed perinatally to thiouracil were substantially reduced or elimated by a 5-week period of "superenriched" postweaning rearing conditions before testing. This treatment resulted in remediation of hypothyroid rats' deficits in maze learning, maze retention, and resistance to extinction of bar-pressing; the facilitative effect persisted for more than 4 months. These behavioral results were consistent with neurohistological findings from studies of early thyroid deficiency and postweaning environmental stimulation in rats.
Asunto(s)
Hipotiroidismo Congénito/terapia , Modelos Animales de Enfermedad , Ambiente , Factores de Edad , Animales , Hipotiroidismo Congénito/inducido químicamente , Hipotiroidismo Congénito/fisiopatología , Extinción Psicológica/fisiología , Femenino , Hipotiroidismo/inducido químicamente , Hipotiroidismo/fisiopatología , Aprendizaje/fisiología , Embarazo , Ratas , Retención en Psicología/fisiología , Tiouracilo
2.
Psychol Rep
; 20(2): 435-45, 1967 Apr.
Artículo
en Inglés
| MEDLINE
| ID: mdl-4962991