RESUMEN
The objective of this study was to investigate the potential of xenograft (cancellous bovine bone) granules to form vital bone in non-natural bone-forming areas of maxillary sinuses. Fourteen sinus augmentations were performed in 14 patients. Surgical outcomes were uneventful, and sufficient radiopaque volume was present radiographically to place dental implants in all sites. Clinical reentry at 6 months revealed bone formation at the osteotomy site. Histologic evaluation of the obtained bone cores revealed that xenograft granules were integrated and surrounded by woven bone and lamellar bone that were in close contact with the particles. The average percentage of newly formed bone at 6 months was 27.5% ± 8.9%. Vital bone formation using the xenograft granules was supported by both clinical and histologic evidence.
Asunto(s)
Regeneración Ósea , Sustitutos de Huesos , Implantación Dental Endoósea/métodos , Seno Maxilar/cirugía , Procedimientos Quirúrgicos Preprotésicos Orales/métodos , Adulto , Humanos , Persona de Mediana EdadRESUMEN
Demineralized bone matrix and cancellous bone chips in a reverse-phase medium carrier (DynaBlast, Keystone Dental) were used to augment the maxillary sinuses in 8 patients requiring 10 sinus augmentations. Clinical reentry after 6 to 7 months (mean, 6.2 months) and computed tomographic scan evaluation at 5 months demonstrated new bone formation as well as sufficient radiopaque volume to place implants in all sites. Microcomputed tomographic evaluation and histomorphometric analysis of sinus core biopsies confirmed the formation of new bone and demonstrated three distinctive mineralization patterns that have been previously described. DynaBlast can be considered a viable alternative to the use of autogenous bone or other types of grafting materials.
Asunto(s)
Matriz Ósea/trasplante , Sustitutos de Huesos , Trasplante Óseo/métodos , Seno Maxilar/cirugía , Procedimientos Quirúrgicos Preprotésicos Orales/métodos , Adulto , Regeneración Ósea , Humanos , Persona de Mediana Edad , Andamios del Tejido , Microtomografía por Rayos XRESUMEN
The objective of this proof-of-principle study was to examine the potential for improved bone regenerative outcomes in maxillary sinus augmentation procedures when recombinant human platelet-derived growth factor BB (0.3 mg/mL) is combined with particulate anorganic bovine bone mineral. The surgical outcomes in all treated sites were uneventful at 6 to 8 months, with sufficient regenerated bone present to allow successful placement of maxillary posterior implants. Large areas of dense, well-formed lamellar bone were seen throughout the intact core specimens in more than half of the grafted sites. Abundant numbers of osteoblasts were noted in concert with significant osteoid in all sites, indicating ongoing osteogenesis. A number of cores demonstrated efficient replacement of the normally slowly resorbing anorganic bovine bone mineral matrix particles with newly formed bone when the matrix was saturated with recombinant human platelet-derived growth factor BB.
Asunto(s)
Regeneración Ósea/efectos de los fármacos , Sustitutos de Huesos , Seno Maxilar/cirugía , Procedimientos Quirúrgicos Preprotésicos Orales , Factor de Crecimiento Derivado de Plaquetas/farmacología , Adulto , Anciano , Animales , Becaplermina , Bovinos , Implantación Dental Endoósea , Femenino , Humanos , Masculino , Persona de Mediana Edad , Minerales , Estudios Prospectivos , Proteínas Proto-Oncogénicas c-sis , Proteínas Recombinantes , Adulto JovenRESUMEN
The amalgam tattoo can often result in an unsightly cosmetic appearance, especially in the maxillary anterior region. The predominant treatment for an amalgam tattoo is the free gingival graft, which also results in a poor cosmetic appearance. The authors would like to review the pathogenesis of the amalgam tattoo and present a new technique that leads to a pleasing cosmetic result.