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1.
Data Brief ; 53: 110052, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38317738

RESUMEN

In the rapidly evolving domain of e-commerce, analyzing customer feedback through reviews is crucial, particularly for understanding and enhancing consumer experience in the Bangladeshi market. Our comprehensive dataset, derived from two Bangladeshi e-commerce platforms, Daraz and Pickaboo, features a diverse collection of reviews in both Bengali and English, covering a broad range of products. These reviews are not only rich in linguistic variety but also encapsulate a spectrum of emotions, some even conveyed through emojis, offering a deep dive into consumer sentiment. Expert annotators have meticulously examined and categorized each review, classifying emotions into five distinct types - Happiness, Sadness, Fear, Anger, and Love - and sentiments into Positive (Happiness, Love) and Negative (Sadness, Anger, Fear) categories. This level of detailed annotation enables precise assessments of customer emotions and preferences, which are essential for evaluating and improving existing product offerings. Moreover, the insights gleaned from this dataset are invaluable for guiding future product development and uncovering new opportunities in the dynamic Bangladeshi market. Ultimately, this dataset not only serves as a significant resource for sentiment analysis using natural language processing (NLP) techniques but also contributes valuable insights into the unique consumer behavior patterns in Bangladesh, enriching the NLP community's understanding of diverse market dynamics.

2.
Glob Med Genet ; 11(1): 29-33, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38239807

RESUMEN

The article explores the multifaceted role of the neuropeptide oxytocin in human behavior and its connection to the oxytocin receptor ( OXTR ) gene. Oxytocin, produced in specific brain nuclei, is implicated in emotional, social, and maternal behaviors, stress reduction, uterine contraction during childbirth, and lactation. The OXTR gene, located on chromosome 3, encodes oxytocin receptors found in various body parts, including critical brain regions associated with social behaviors. The article delves into studies on rodents, revealing correlations between OXTR gene expression and pair bonding in the prefrontal cortex and social behavior regulation in the amygdala. The discussion extends to the impact of oxytocin on social support-seeking behavior, focusing on a specific genetic variation, rs53576. The article explores how this genetic variation influences empathy, stress reactivity, and susceptibility to disorders such as autism and social anxiety. Furthermore, the article examines structural and functional changes in the brain associated with OXTR gene variations. It discusses the role of DNA methylation in influencing oxytocin receptor availability, affecting social perception and responsiveness to negative stimuli. The article also highlights the oxytocinergic system's involvement in disorders such as autism and social anxiety, emphasizing the interplay between genetics and environmental factors. The article also touches on the potential therapeutic use of exogenous oxytocin in mitigating symptoms associated with these disorders. In summary, the article underscores the intricate relationship between oxytocin, the OXTR gene, and diverse aspects of human behavior, providing insights into social bonding, perception, and the development of behavioral disorders.

3.
PLoS One ; 18(6): e0286975, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37307261

RESUMEN

Genetic variations are a crucial source of germplasm heterogeneity, as they contribute to the development of new traits for plant breeding by offering an allele resource. Gamma rays have been widely used as a physical agent to produce mutations in plants, and their mutagenic effect has attracted much attention. Nonetheless, few studies have examined the whole mutation spectrum in large-scale phenotypic evaluations. To comprehensively investigate the mutagenic effects of gamma irradiation on lentils, biological consequences on the M1 generation and substantial phenotypic screening on the M2 generation were undertaken. Additionally, the study followed the selected mutants into the M3 generation to evaluate the agronomic traits of interest for crop improvement. Seeds of lentil variety Moitree were irradiated with a range of acute gamma irradiation doses (0, 100, 150, 200, 250, 300, and 350 Gy) to induce unique genetic variability. This research focused on determining the GR50 value while considering seedling parameters and examining the status of pollen fertility while comparing the effects of the gamma irradiation dosages. The GR50 value was determined to be 217.2 Gy using the seedling parameters. Pollens from untreated seed-grown plants were approximately 85% fertile, but those treated with the maximum dosage (350 Gy) were approximately 28% fertile. Numerous chlorophyll and morphological mutants were produced in the M2 generation, with the 300 Gy -treated seeds being the most abundant, followed by the 250 Gy -treated seeds. This demonstrated that an appropriate dosage of gamma rays was advantageous when seeking to generate elite germplasm resources for one or multiple traits. Selected mutants in the M3 generation showed improved agronomic traits, including plant height, root length, number of pods per plant, and yield per plant. These investigations will contribute to a comprehensive understanding of the mutagenic effects and actions of gamma rays, providing a basis for the selection and design of suitable mutagens. This will facilitate the development of more controlled mutagenesis protocols for plant breeding and help guide future research directions for crop improvement using radiation-induced mutation breeding techniques.


Asunto(s)
Lens (Planta) , Rayos gamma , Fitomejoramiento , Mutágenos , Clorofila , Fenotipo
4.
Plants (Basel) ; 12(4)2023 Feb 08.
Artículo en Inglés | MEDLINE | ID: mdl-36840110

RESUMEN

In the scenario of global climate change, understanding how plants respond to drought is critical for developing future crops that face restricted water resources. This present study focuses on the role of WRKY transcription factors on drought tolerance in tomato, Solanum lycopersicum L., which is a significant vegetable crop. WRKY transcription factors are a group of proteins that regulate a wild range of growth and developmental processes in plants such as seed germination and dormancy and the stress response. These transcription factors are defined by the presence of a DNA-binding domain, namely, the WRKY domain. It is well-known that WRKY transcription factors can interact with a variety of proteins and therefore control downstream activities. It aims to simulate the effect of curcumin, a bioactive compound with regulatory capacity, on the protein-protein interaction events by WRKY transcription factors with an emphasis on drought stress. It was found that curcumin binds to WRKY with an energy of -11.43 kcal/mol with inhibitory concentration (Ki) 0.12 mM and has the potential to improve fruit quality and reinforce drought tolerance of S. lycopersicum, according to the results based on bioinformatics tools. The root means square deviation (RMSD) of the C-α, the backbone of 2AYD with ligand coupled complex, displayed a very stable structure with just a little variation of 1.89 Å. MD simulation trajectory of Cα atoms of 2AYD bound to Curcumin revealed more un-ordered orientation in PC1 and PC10 modes and more toward negative correlation from the initial 400 frames during PCA. Establishing the binding energies of the ligand-target interaction is essential in order to characterize the compound's binding affinity to the drought transcription factor. We think we have identified a phyto-agent called curcumin that has the potential to enhance the drought tolerance. Compared to the part of the mismatch repair-base technique that can be used to fix drought related genes, curcumin performed better in a drop-in crop yield over time, and it was suggested that curcumin is a potential candidate factor for improving drought tolerance in tomatoes, and it needs future validation by experiments in laboratory and field.

5.
J Adv Vet Anim Res ; 10(4): 794-800, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38370881

RESUMEN

Objectives: Lead (Pb), a toxic heavy metal, is a serious concern for poultry that negatively affects their productivity and health. To combat those issues efficiently, it is necessary to include feed supplements that have rich antioxidant properties for satisfactory health and productivity. Spirulina platensis (Sp), a microalgae, is a compound that provides several health benefits for humans and animals. This study explores that supplementation of Sp in diet as well as in water reduces the burden of Pb in different tissues, improves hematology, and improves the productive performance of advanced-age laying hens. Materials and methods: Forty birds were separated into four groups: the control (C), Spirulina (Sp), Pb, and (Pb + Sp) groups. The Pb group was given Pb acetate at a dose of 2 gm/l in water ad libitum for 4 weeks. Sp group was fed Sp at a dose of 4 gm/kg feed. The Pb + Sp group was given Pb and Sp as in the previous groups. Results: Productive performance and hematology such as hemoglobin (Hb), packed cell volume, red blood cell, mean corpuscular volume, mean corpuscular Hb (MCH) concentration, and MCH were significantly (p < 0.05) decreased in Pb-treated groups compared to controls. The distribution of Pb concentration was highest in the bones and lowest in the gizzard. However, Sp treatment significantly (p < 0.05) increased the productive performance and the hematological parameters. Moreover, Pb concentration in different organs significantly decreased in the group treated with Sp. Conclusion: This study indicates that Sp can possibly be used as a natural and powerful dietary additive to mitigate heavy metal intoxication in chickens, thereby being efficient and effective for production.

6.
J Fungi (Basel) ; 8(6)2022 May 26.
Artículo en Inglés | MEDLINE | ID: mdl-35736050

RESUMEN

Clonostachys rosea is an important mycoparasite, with great potential for controlling numerous plant fungal diseases. Understanding the mechanisms and modes of action will assist the development and application of this biocontrol fungus. In this study, the highly efficient C. rosea 67-1 strain was marked with the green fluorescent protein (GFP), and the transformant possessed the same biological characteristics as the wild-type strain. Fungal interactions with Botrytis cinerea during co-culture and encounter on tomato leaves were assessed by fluorescence confocal and electron microscopy. The results indicated that once the two fungi met, the hyphae of C. rosea grew alongside those of B. cinerea, then attached tightly to the host and developed special structures, via which the biocontrol fungus penetrated the host and absorbed nutrients, eventually disintegrating the cells of the pathogen. Mycoparasitism to B. cinerea was also observed on tomato leaves, suggesting that C. rosea can colonize on plants and act following the invasion of the pathogenic fungus.

7.
J Nutr Sci Vitaminol (Tokyo) ; 67(1): 13-20, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33642460

RESUMEN

A population based cross-sectional study was conducted in four residential areas of Tangail Sadar Upazila, Bangladesh aiming to explore the knowledge about vitamin A fortified edible oils and rice as well as the their consumption rate. A total of 400 participants were randomly selected. Data were collected through face to face interviews. Only 15.0% and 3.5% participants had knowledge about vitamin A fortified edible oils and rice respectively. Precisely vitamin A fortified edible oils knowledge level was found inferior in rural (11.7%) and slum (0%) than urban (48.3%) and semi-urban (40.0%) participants. Knowledge about vitamin A fortified rice was found higher in urban (78.6%) than rural (14.3%) and slum (0%) participants. Most of the participants received knowledge through advertisements (N=45 and N=12 for fortified oils and rice respectively). Maximum participants (62.3%) did not consume vitamin A fortified edible oils and consumption rate in rural (11.8%) and slum (10.2%) areas were poorer than urban (53.5%) and semi-urban (24.4%) areas. Consumption rate of vitamin A fortified rice was found nil in all the study areas. Lack of knowledge about vitamin A fortified rice and oils accounted solely for poor consumption. Knowledge level about vitamin A fortified edible oils and rice and consumption rate were found statistically significantly (p<0.05) with participant's place of residences, education level and monthly income. Finally, this study indicates that the overall knowledge level and consumption rate of vitamin A fortified edible oils and rice is poor especially in rural and slum populations in Tangail Sadar Upazila.


Asunto(s)
Oryza , Vitamina A , Bangladesh , Estudios Transversales , Alimentos Fortificados/análisis , Humanos , Aceites de Plantas , Vitamina A/análisis
8.
Front Microbiol ; 11: 1640, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32760382

RESUMEN

Cell wall biogenesis protein phosphatases play important roles in various cellular processes in fungi. However, their functions in the widely distributed mycoparasitic fungus Clonostachys rosea remain unclear, as do their potential for controlling plant fungal diseases. Herein, the function of cell wall biogenesis protein phosphatase CrSsd1 in C. rosea 67-1 was investigated using gene disruption and complementation approaches. The gene-deficient mutant ΔCrSsd1 exhibited much lower conidiation, hyphal growth, mycoparasitic ability, and biocontrol efficacy than the wild-type (WT) strain, and it was more sensitive to sorbitol and Congo red. The results indicate that CrSsd1 is involved in fungal conidiation, osmotic stress adaptation, cell wall integrity, and mycoparasitism in C. rosea.

9.
J Vis ; 17(9): 22, 2017 08 01.
Artículo en Inglés | MEDLINE | ID: mdl-28837968

RESUMEN

Performance in detection tasks can be improved by directing attention to task-relevant features. In this study, we evaluate the direction tuning of selective attention to motion features when observers detect point-light biological motion in noise. Feature-based attention strategy is assessed by capitalizing on the sensitivity of unattended steady-state visual-evoked potential (SSVEP) to the spreading of feature-based attention to unattended regions of space. Participants monitored for the presence of a point-light walker embedded in uniform dynamic noise in the center of the screen. We analyzed the phase-locked electroencephalogram response to a flickering random-dot kinematogram (RDK) in an unattended peripheral annulus for the 1 s prior to the onset of the target. We found the highest SSVEP power to originate from electrodes over posterior parietal cortex (PPC), with power modulated by the direction of motion in the unattended annulus. The SSVEP was strongest on trials in which the unattended motion was opposite the facing direction of the walker, consistent with the backstroke of the feet and with the global direction of perceived background motion from a translating walker. Coherence between electrodes over PPC and other brain regions successfully predicted individual participant's d-prime, with the highest regression coefficients at electrodes over ventrolateral prefrontal cortex (VLPFC). The findings are evidence that functional connectivity between frontal and parietal cortex promote perceptual feature-based attention, and subsequent perceptual sensitivity, when segregating point-light figures from masking surround.


Asunto(s)
Atención/fisiología , Potenciales Evocados Visuales/fisiología , Percepción de Movimiento/fisiología , Lóbulo Parietal/fisiología , Adulto , Mapeo Encefálico , Electroencefalografía , Femenino , Humanos , Masculino , Adulto Joven
10.
J Pediatr ; 166(3): 576-81, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-25477158

RESUMEN

OBJECTIVES: To describe the demographic and clinical characteristics of children for whom claims were filed with the National Vaccine Injury Compensation Program (VICP) alleging seizure disorder and/or encephalopathy as a vaccine injury. STUDY DESIGN: The National VICP within the Department of Health and Human Services compensates individuals who develop medical problems associated with a covered immunization. We retrospectively reviewed medical records of children younger than 2 years of age with seizures and/or encephalopathy allegedly caused by an immunization, where a claim was filed in the VICP between 1995 through 2005. RESULTS: The VICP retrieved 165 claims that had sufficient clinical information for review. Approximately 80% of these alleged an injury associated with whole-cell diphtheria, pertussis (whooping cough), and tetanus or tetanus, diphtheria toxoids, and acellular pertussis vaccine. Pre-existing seizures were found in 13% and abnormal findings on a neurologic examination before the alleged vaccine injury in 10%. A final diagnostic impression of seizure disorder was established in 69%, of whom 17% (28 patients) had myoclonic epilepsy, including possible severe myoclonic epilepsy of infancy. Specific conditions not caused by immunization, such as tuberous sclerosis and cerebral dysgenesis, were identified in 16% of subjects. CONCLUSION: A significant number of children with alleged vaccine injury had pre-existing neurologic or neurodevelopmental abnormalities. Among those developing chronic epilepsy, many had clinical features suggesting genetically determined epilepsy. Future studies that include genotyping may allow more specific therapy and prognostication, and enhance public confidence in vaccination.


Asunto(s)
Síndromes de Neurotoxicidad/etiología , Convulsiones/etiología , Vacunación/efectos adversos , Vacunas/efectos adversos , Preescolar , Femenino , Humanos , Incidencia , Lactante , Recién Nacido , Masculino , Síndromes de Neurotoxicidad/epidemiología , Estudios Retrospectivos , Factores de Riesgo , Convulsiones/epidemiología , Tasa de Supervivencia , Estados Unidos/epidemiología
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