Factors Related to Masticatory Rhythm in Patients with Oral Tumors.

Background: Older adults who have undergone surgery for oral tumors are at increased risk of impaired masticatory rhythm. This study investigated the correlations between masticatory rhythm, objective masticatory performance, and subjective masticatory performance as well as factors related to masticatory rhythm. Methods: The participants were 44 adults (24 men, 20 women; age range 42~90 years old) who had undergone maxillectomy, mandibulectomy, or glossectomy and were rehabilitated with a maxillofacial prosthesis. The number of functional contact teeth pairs was confirmed by intraoral examination. Chewing rate, cycle duration, coefficient of variation (CV) for cycle duration (reflecting the stability of masticatory rhythm), and mixing ability were measured simultaneously using a mastication movement rhythm tracking device during gum chewing. Maximum occlusal force was measured using the dental prescale system. Patients' perception of chewing ability was rated using a questionnaire. Results: The Spearman's rank correlation test revealed that mixing ability, patient-rated masticatory scores, cycle duration, CV for cycle duration, and maximum occlusal force showed significant correlations with chewing rate. Multiple linear regression analysis identified mixing ability and the CV for cycle duration as significant predictors of masticatory rhythm. Conclusions: Factors associated with a faster chewing rate were higher mixing ability and masticatory scores, greater maximum occlusal force, shorter cycle duration, and smaller CV for cycle duration. Stable masticatory rhythm and mixing ability are significant predictors of chewing rate. Poor masticatory performance and unstable masticatory rhythm can result in slower chewing and thus a higher risk of inadequate dietary intake.

Frequently used extraoral maxillofacial prosthetic materials and their longevity - A comprehensive review.

The longevity of an extraoral prosthesis depends on its physical and mechanical properties and user maintenance. Faced with multiple outcome measures, researchers find it difficult to determine the most appropriate extraoral prosthetic material. This comprehensive review evaluates the most used extraoral prosthesis materials and qualitatively assesses their longevity and function. The study aims to identify and interpret the results of current updates on the factors that affect longevity and functionality. This comprehensive review summarizes and evaluates differences in the properties of commonly used extraoral maxillofacial prosthetic materials. The review was planned to focus on all factors related to the longevity and function of the extraoral maxillofacial prosthetics. An electronic search covered English articles in PubMed, Scopus, Google Scholar, Web of Science, and grey literature. Manual searching was also performed. Six authors participated in the screening. Search engines extracted 1107 records, and 88 studies were included for qualitative and bias assessments. Silicones are the most frequently used extraoral maxillofacial prosthetic materials. Heat-cured silicones are more color-stable than those cured at room temperature. Additional ingredients and processing techniques affect prosthesis longevity.

Predicting maximum occlusal force and tongue pressure using decision tree analysis in patients diagnosed with head and neck tumors.

STATEMENT OF PROBLEM: Preserving and restoring oral functions, especially mastication and swallowing, is important to the quality of life of patients being treated for head and neck tumors. Studies that help predict maximum occlusal force and tongue pressure during prosthetic treatment, necessary for providing comprehensive, appropriate treatment and encouraging patient adherence and confidence are lacking. PURPOSE: The purpose of this clinical study was to develop a decision tree model for predicting maximum occlusal force and tongue pressure in patients diagnosed with head and neck tumors that could help both experienced and less experienced prosthodontists and oral surgeons optimize the treatment plan and support patient compliance and their quality of life. MATERIAL AND METHODS: A total of 80 patients who had been treated for head and neck tumors were enrolled in the study. Their maximum occlusal force was measured using a pressure-sensitive film and tongue pressure using a tongue pressure measurement device. Data, including basic characteristics, were transferred to a comma separated values file, which was then imported into a statistical software package to produce a decision tree. The classification and regression tree method was used to construct a predictive model. RESULTS: The number of occlusal contacts associated with not wearing a prosthesis, flap reconstruction, radiotherapy, chemotherapy, the number of teeth present, age, tumor stage, and tumor type were found to be associated with maximum occlusal force, with a prediction accuracy of 96.3%, area under the receiver operating characteristic curve of 0.99, sensitivity of 97%, and specificity of 94%. The number of occlusal contacts associated with wearing and not wearing a prosthesis, tumor stage, age, radiotherapy, and surgery type were found to be associated with tongue pressure, with a prediction accuracy of 96.3%, area under the receiver operating characteristic curve of 0.97, sensitivity of 97%, and specificity of 93%. CONCLUSIONS: The decision tree model can be an effective tool for the prediction of maximum occlusal force and tongue pressure in patients diagnosed with head and neck tumors, helping both experienced and less experienced prosthodontists and oral surgeons to provide early, appropriate, and necessary treatment before starting prosthetic treatment and helping patients with treatment compliance and communication with medical staff.

Assessment of the color stability of two silicone elastomers for maxillofacial prostheses upon exposure to cold beverages.

PURPOSE: This study investigated the color stability of different commercially available silicone materials for facial prostheses upon exposure to everyday beverages. It was hypothesized that the beverages would not alter the color of the silicone under conditions simulating daily exposure. METHODS: Sixty specimens were fabricated using two materials - VST-50 and Silfy - and exposed to commercially available cold mineral water, tea, or coffee. Specimen color was evaluated on days 1 and 15. The color was measured with a spectrophotometer based on CIELab system and color differences were calculated as ΔE. Statistical analysis was performed using the Kruskal-Wallis test and Mann-Whitney U test. RESULTS: The mean ΔE values after 15 days of exposure to mineral water, cold green tea, and coffee were 1.016, 3.480, and 3.636 for VST-50 and 0.440, 0.798, and 1.425 for Silfy, respectively. Both materials showed significant differences in color, and VST-50 showed a greater color change than Silfy, especially for coffee. CONCLUSION: Pigmented silicone elastomers have low color stability, leading to an overall color change in silicone prostheses when exposed to pigmented beverages. Color changes in such prostheses can be mitigated by selecting materials with better color stability to extend their longevity.

Evaluation of the color stability of three maxillofacial silicone materials after exposure to beverages: An in vitro study.

Purpose: Oral cancer often requires treatments like surgical intervention, involving surgical resection of lips and other facial parts. For those patients, prosthetic rehabilitation following surgery promotes social reintegration. This study explores the color stability of various commercially available silicone materials for facial prostheses when exposed to everyday beverages like coffee and tea. The hypothesis is that these beverages can induce color changes in silicones, simulating conditions of daily use. Material and methods: A total of 90 specimens were fabricated. There were 30 specimens deefor each of 3 nonpigmented silicone elastomers: Silfy, A-2186-F and VST-50 and were immersed in tea or coffee at drinking temperature and evaluated for color changes at time points of 0 h, 1 h, and 6 h. The color was measured with a colorimeter that used the CIE L*a*b* system and the color change ΔΕ was calculated to quantify the color change. Statistical analysis was performed by using the Kruskal-Wallis test, the Mann-Whitney U test, and the Wilcoxon signed-rank Test. The threshold for statistical significance was P < .05. Results: Color change was observed for each of the silicones exposed to the beverages (P < .05). The value of ΔE was significantly higher for A-2186-F compared with VST-50 and Silfy (P < .05 in all beverages at 6 h). The color of the elastomers progressively changed while immersed in the beverages over 6 h. The change in color was significantly greater for coffee compared with tea (P < .05). Conclusions: The color stability of nonpigmented silicone elastomers is inherently low, which contributes to the overall color change of silicone prostheses when they are exposed to beverages that contain pigments. The elastomer A-2186-F had greatest values of ΔE among the materials tested. Color changes of silicone prostheses can be lessened by selecting materials with consideration of color stability to improve their longevity and extend their period of use.

Case report of a patient with mandibulectomy followed up for 11 years.

Mandibular deviation and rotation following mandibulectomy can significantly impact oral function and quality of life. The postoperative course of a 57-year-old patient who underwent mandibulectomy for oral cancer and findings over 11 years of follow-up observation to monitor changes in the mandibular position are described here. Based on the observations, it is important to raise awareness regarding the necessity of continued monitoring of mandible position and regular adjustments of prostheses for patients who have undergone mandibulectomy.

Creating and analyzing digital scans of a mandibulectomy cast with simulated trismus.

STATEMENT OF PROBLEM: Trismus associated with maxillofacial defects resulting from tumor resection or radiotherapy can make dental treatment uncomfortable for patients. Using an intraoral scanner instead of making a conventional impression could help to make prosthetic rehabilitation more comfortable. However, limited information is available regarding the feasibility and accuracy of intraoral scanners for scanning mandibular defects. PURPOSE: The purpose of this in vitro study was to evaluate the feasibility and accuracy of using an intraoral scanner to digitize a cast of a mandibular defect under various simulated trismus conditions. MATERIAL AND METHODS: An intraoral scanner was used to scan the mandibular cast under different simulated degrees of trismus (mouth opening 10, 20, and 30 mm) and nontrismus (mouth opening 40 mm). The surface areas captured were compared. The datasets were loaded into a 3-dimensional (3D) evaluation software program and then superimposed for precision analysis and on reference data for trueness analysis. One-way analysis of variance was used to compare surface area captured, precision, and trueness of the measurement under the different mouth opening conditions (α=.05). RESULTS: The surface area for which 3D data were obtained by the intraoral scanner ranged from 3199.1 to 6161.6 mm2. The area differed significantly under all mouth opening conditions (P=.001), with a smaller scanned surface area captured in severe trismus (10 mm). Precision ranged from 0.032 to 0.056 mm, and trueness from 0.037 to 0.076 mm. No significant differences were seen in precision (P=.312), but significant differences were seen in trueness (P=.016) under all trismus conditions. CONCLUSIONS: Using an intraoral scanner appears feasible for digitizing mandibular defect casts with simulated mild and moderate trismus. The accuracy of the obtained data was clinically acceptable.

Meta-reinforcement learning via orbitofrontal cortex.

The meta-reinforcement learning (meta-RL) framework, which involves RL over multiple timescales, has been successful in training deep RL models that generalize to new environments. It has been hypothesized that the prefrontal cortex may mediate meta-RL in the brain, but the evidence is scarce. Here we show that the orbitofrontal cortex (OFC) mediates meta-RL. We trained mice and deep RL models on a probabilistic reversal learning task across sessions during which they improved their trial-by-trial RL policy through meta-learning. Ca2+/calmodulin-dependent protein kinase II-dependent synaptic plasticity in OFC was necessary for this meta-learning but not for the within-session trial-by-trial RL in experts. After meta-learning, OFC activity robustly encoded value signals, and OFC inactivation impaired the RL behaviors. Longitudinal tracking of OFC activity revealed that meta-learning gradually shapes population value coding to guide the ongoing behavioral policy. Our results indicate that two distinct RL algorithms with distinct neural mechanisms and timescales coexist in OFC to support adaptive decision-making.

Detailed speech evaluation including formant 3 analysis and voice visualization in maxillofacial rehabilitation: A clinical report.

Objective speech evaluation such as analysis of formants 1 and 2 and nasality measurement have been used in maxillofacial rehabilitation for outcome assessment. However, in some patients, those evaluations are insufficient to assess a specific or unique problem. This report describes the use of a new speech evaluation including formant 3 analysis and voice visualization in a patient with a maxillofacial defect. The patient was a 67-year-old man who had a maxillary defect that opened to the maxillary sinus and who had an unnatural voice even when wearing an obturator. Nasality was low and the frequency of formants 1 and 2 were normal even without the obturator. However, a low frequency of formant 3 and a shifted center of voice were observed. These results indicated that the unnatural voice was related to increased resonant volume in the pharynx rather than hypernasality. This patient demonstrates that advanced speech analysis can be useful for detecting the cause of speech disorder and planning maxillofacial rehabilitation.

A 20-year clinical survey of radiotherapy prostheses at the Clinic for Maxillofacial Prosthetics of Tokyo Medical and Dental University Hospital.

PURPOSE: To identify secular trends in the use of radiotherapy prostheses in the Clinic for Maxillofacial Prosthetics at Tokyo Medical and Dental University Hospital and to ascertain patient characteristics and future needs. METHODS: The study included all patients who visited the clinic between January 1, 2000, and December 31, 2019. Data on numbers of cases, gender and age, numbers and types of radiotherapy prostheses, primary cancer site, and time required for prosthesis fabrication during the study period were collected from medical records and retrospectively analyzed. RESULTS: During the 20-year study period, 1,066 prostheses were fabricated for 1,135 cases. In most years, at least 60% of cases were male. The mean age increased from 60.6 to 67.1 years during the study period, and the number of cases older than 70 years increased over time. The most common cancer site was the tongue, and the most common type of radiotherapy prosthesis was a spacer. The mean time for spacer fabrication was 11 days. CONCLUSION: During a recent 20-year period, mean age and the proportion of elderly patients requiring savers increased. When treating elderly patients, prosthodontists responsible for fabricating radiotherapy prostheses must collaborate effectively with radiation oncologists.

Use of an occlusal ramp for rehabilitation after a mandibulectomy and its effects on mastication.

STATEMENT OF PROBLEM: Patients with a mandibular defect can develop mandibular deviation, resulting in a loss of or reduction in occlusal contact and ultimately loss of function. The occlusal ramp is a prosthesis used to help restore the masticatory function of such patients and is used particularly in the maxillofacial rehabilitation of patients with masticatory dysfunction resulting from mandibular deviation. The occlusal ramp is usually attached to a mandibular denture or worn as an independent device placed on the palate corresponding to the mandible that produces the offset. However, evidence of the effects of its use is sparse. PURPOSE: The purpose of this clinical study was to investigate the effects of occlusal ramp use in functional rehabilitation. MATERIALS AND METHODS: This study included 10 patients who had received mandibulectomies (5 men and 5 women; mean age 76.7 years, range 67 to 90 years) with deviation of the mandible. An occlusal ramp was fabricated for each participant as part of their maxillofacial prosthetic treatment. Masticatory performance was evaluated before and after the treatment by measuring glucose extraction while masticating a piece of gummy jelly. The Wilcoxon signed-rank test was used for statistical analysis (α=.05). RESULTS: The median masticatory performance score, represented as glucose concentration (mg/dL), was 82.45 before treatment and 115.45 after treatment, with an overall improvement of 33.00. Scores differed significantly before and after treatment (P=.005). Masticatory performance for each participant improved in the range of 17.7 to 103.3, highlighting the role that the occlusal ramp played in mastication, although with differing effects in each participant. CONCLUSIONS: Masticatory performance in participants with mandibular deviation after a mandibulectomy was significantly improved with an occlusal ramp. This suggests the effectiveness of using occlusal ramps in maxillofacial prosthetic treatment for the recovery of masticatory function in patients with mandibular deviation.

Three-dimensional evaluation of the dental arch in cleft lip and palate after prosthetic treatment.

PURPOSE: This study aimed to evaluate the stability of the surface of the maxillary teeth and mucosa in cleft lip and palate (CLP) patients with a maxilla defect or tissue deficiency according to the duration of observation and cleft type. METHODS: Pairs of maxillary casts taken from 18 patients at different time points after prosthodontic treatment were investigated in this study. All 36 casts were scanned with an intraoral scanner, and the acquired images were saved in standard tesselation language (STL) files. The two STL files for each patient were then superimposed using three-dimensional (3D) evaluation software, with 3D deviations shown as a color map. Areas with a 3D deviation within ±0.100 mm were defined as stable. The influence of cleft type and duration of observation on the ratio of stable areas to the entire maxillary surface comprising the teeth and mucosa was investigated using multiple regression analysis. Statistical significance was set at p <0.05. RESULTS: Multiple regression analysis showed that the duration of observation was significantly associated with the stable area ratio (B = -23.463, P<.001), whereas cleft type was not (ß = 0.13, P = 0.301). CONCLUSIONS: The maxillary teeth and mucosa of CLP patients changed over time, with stable areas showing a negative correlation with the observation period. However, the stability of the dental arch was not significantly affected by the cleft type. 3D analysis of the casts of CLP patients allowed for measurements and to accurately assess relapse of the maxillary arch after prosthetic treatment.

Evaluating the Feasibility and Accuracy of Digitizing a Maxillary Defect Model Simulating Various Trismus Conditions.

PURPOSE: To compare the feasibility and accuracy of using intraoral scanners to digitize a maxillary defect model simulating various trismus conditions. MATERIALS AND METHODS: Four intraoral scanners were used to digitize a maxillary defect model simulating four different degrees of trismus (mouth opening = 10, 20, 30, and 40 mm), and the scanned areas were compared. The scans were also superimposed on each other for precision analysis and on reference data for trueness analysis using 3D evaluation software. Two-way ANOVA was used to compare area, precision, and trueness among scanners and among conditions. RESULTS: The surface area for which 3D data were obtained by the intraoral scanners ranged from 2,672 to 6,613 mm2. Significant differences were observed between the scanners (P < .001) and between the trismus conditions (P < .001), with a smaller scanned surface area in severe trismus (10 mm). Trueness ranged from 0.033 to 0.301 mm, and precision from 0.022 to 0.397 mm. Significant differences in trueness and precision values were found among the scanners (P = .001 and P = .001, respectively), but not the trismus conditions (P = .260 and P = .075, respectively). CONCLUSION: Although trueness and precision differed between intraoral scanners, digitization of the maxillectomy model simulating various trismus conditions appears to be feasible from the perspective of accuracy with all of the scanners used. The smaller scanned surface area in the severe trismus condition was due to lack of data on the defect site in that condition.

Effect of cut-out rescan procedures on the accuracy of an intraoral scanner used for digitizing an ear model: An in vitro study.

PURPOSE: The purpose of this study was to evaluate the impact of the rescanning of mesh holes of different diameters on the accuracy of an intraoral scanner (IOS) used to digitize an ear model. MATERIALS AND METHODS: An ear model was digitized using an intraoral scanner (Medit i500) to obtain a reference mesh. A baseline experimental scan was created by editing a duplicate of the reference mesh using the cut-out tool of the IOS software. Three equal groups were created based on the diameter of the cut-out areas: 2 mm (G1), 5 mm (G2), and 8 mm (G3) (n = 15). The cut-out areas were rescanned and a total of 45 digital files were exported. The discrepancy between the reference and the experimental digital scans was measured using the root mean square calculation (RMS). The data were analyzed by a Kruskal-Wallis test followed by a post hoc Dunn's test with Bonferroni correction. RESULTS: The trueness values ranged from 19.53 to 27.13 µm. There were significant differences in the RMS error values among the groups tested (p < 0.001) and post hoc multiple comparisons showed significant differences between the G1 and G2 groups (p = 0.04), G1 and G3 groups (p < 0.001), and G2 and G3 groups (p = 0.004). Overall, the precision values ranged from 4.93 to 7.73 µm and significant differences in the RMS values were only found between the G1 and G2 groups (p = 0.014). CONCLUSIONS: Mesh hole rescanning affected the scanning accuracy (trueness and precision) of the IOS tested. The larger the diameter of the mesh holes, the less the trueness of the IOS tested. The precision values seemed to be less affected compared with the trueness by the cut-out and rescanning procedures.

Digital acoustic analysis of the first three formant frequencies in patients with a prosthesis after maxillectomy.

STATEMENT OF PROBLEM: Prosthetic rehabilitation with an obturator can help to restore or improve the intelligibility of speech in patients after maxillectomy. The frequency of formants 1 and 2 as well as their ranges were initially reported in patients with maxillary defects in 2002, and the evaluation method that was used is now applied in clinical evaluation. However, the details of formant 3 are not known and warrant investigation because, according to speech science, formant 3 is related to the pharyngeal volume. Clarifying the formant frequency values of formant 3 in patients after maxillectomy would enable prosthodontists to refer to these data when planning treatment and when assessing the outcome of an obturator. PURPOSE: The purpose of this clinical study was to determine the acoustic characteristics of formant 3, together with those of formants 1 and 2, by using a digital acoustic analysis during maxillofacial prosthetic treatment. The utility of determining formant 3 in the evaluation of speech in patients after maxillectomy was also evaluated. MATERIAL AND METHODS: Twenty-six male participants after a maxillectomy (mean age, 63 years; range, 20 to 93 years) were included, and the 5 Japanese vowels /a/, /e/, /i/, /o/, and /u/ produced with and without a definitive obturator prosthesis were recorded. The frequencies of the 3 formants were determined, and their ranges were calculated by using a speech analysis system (Computerized Speech Lab CSL 4400). The Wilcoxon signed rank test was used to compare the formants between the 2 use conditions (α=0.05). RESULTS: Significant differences were found in the frequencies and ranges of all 3 formants between the use conditions. The ranges of all 3 formants produced with the prosthesis were significantly greater than those produced without it. CONCLUSIONS: Based on the findings, both the first 2 formants and the third formant were changed by wearing an obturator prosthesis. Because formant 3 is related to the volume of the pharynx, evaluation of this formant and its range can reflect the effectiveness of the prosthesis to seal the oronasal communication and help reduce hypernasality, suggesting the utility of formant 3 analysis in prosthodontic rehabilitation.

Computerized optical scanning of ears: An in vitro evaluation with an intraoral scanner.

STATEMENT OF PROBLEM: Making conventional facial impressions can be uncomfortable for the patient and complicated for the prosthodontist. Using facial scanners to digitize faces is an alternative approach. However, the initial costs of the equipment have prevented their widespread use in dental practice, and the accuracy of ear scanning is unclear. PURPOSE: The purpose of this in vitro study was to investigate the accuracy of a widely used intraoral scanner for digitizing an ear model. MATERIAL AND METHODS: For reference, a silicone model of an ear was scanned with an industrial scanner. Then, the model was scanned 5 times with an intraoral scanner. Five conventional impressions of the model were made with a hydrocolloid impression material and poured with dental stone. The stone casts were then digitized with a desktop scanner. The data sets acquired with the 3 approaches were analyzed by using a 3-dimensional (3D) evaluation software program. Trueness and precision values were calculated for each approach. Linear mixed models with random intercepts were fitted to each sample to evaluate the effects of the impression method on mean deviations (α=.05). RESULTS: Mean ±standard deviation trueness and precision values were 0.097 ±0.012 mm and 0.033 ±0.015 mm, respectively, for the digital scan, and 0.092 ±0.022 mm and 0.081 ±0.024 mm for the conventional impression, showing a significantly lower deviation in precision for the digital approach (P<.001). CONCLUSIONS: The feasibility of digitizing an ear efficiently by using the investigated intraoral scanner was demonstrated, and similar trueness and significantly better precision values were achieved than when using conventional impressions. These promising results suggest the need for clinical investigations.

Case Report: Psychoacoustic Analysis of a Clarinet Performance With a Custom-Made Soft Lip Shield Worn to Prevent Mucosal Erosion of Lower Lip.

Introduction: Wind instrument players sometimes suffer from erosion of the mucous membrane of the lip. This is caused by the action and pressure of the mouthpiece of the wind instrument against teeth. To address this problem, a lip shield is fitted over the dental arch to prevent direct contact between the lips and teeth. However, there are a few studies on the influence of the lip shield on the acoustics of wind instruments. The purpose of this study was to analyze the psychoacoustics of a clarinet performance with the player wearing a custom-made soft lip shield to prevent mucosal erosion of the lower lip. Case Description: A lip shield was custom-made with a soft thermoplastic material for a female clarinetist who complained of mucosal erosion and pain of the lower lip. The psychoacoustics of her musical performance played in different dynamics, fortissimo, mezzo forte and pianissimo were analyzed, including loudness and sharpness. A self-evaluation questionnaire with items rated on a 10-point scale was administered. After wearing the lip shield, the patient reported that the mucosal erosion and pain of her lower lip when playing clarinet resolved. The lip shield had little effect on the loudness. There was a slight decrease in sharpness when the lip shield was worn compared to when it was not, describing the reduction of high frequencies. Furthermore, fewer variations in sharpness between the tones were observed. Conclusion: The results suggest that lip shields made of soft materials can eliminate mucosal erosion and pain of the lower lip while having little effect on performance, although, a slight change in timbre is possible.

The rising challenge of mucormycosis for maxillofacial prosthodontists in the Covid-19 pandemic: A literature review.

PURPOSE: This review examines the importance of prosthetic rehabilitation after surgical treatment of mucormycosis in the context of expected increases in cases during the current COVID-19 pandemic. STUDY SELECTION: Google Scholar, Web of Science, Scopus, and PubMed databases were searched for relevant articles published between 2010 and 2021. Articles that provided a full description of prosthetic treatment after surgical treatment of mucormycosis were included in the review. RESULTS: Out of 30 articles describing orofacial prosthetic rehabilitation after surgical treatment of mucormycosis published during the 12-year target period, 19 reported patients with diabetes, two described mucormycosis as a post-COVID-19 complication, and 25 were reports from India. Most of the prosthetic treatments used a definitive obturator (63.3%) either alone or in combination with other forms of prosthetic rehabilitation. Other prosthetic strategies included an orbital prosthesis (26.6%), a facial prosthesis with or without a nasal replacement (16.6%), a surgical or interim obturator, a conventional complete denture, and a cast partial denture. Six articles (20%) mentioned the use of combined prosthetic rehabilitation involving multiple regions of the face and oral cavity. CONCLUSION: Prosthetic rehabilitation after surgical treatment of mucormycosis is essential for the early restoration of oral function and facial esthetics. Given the aggressive nature of mucormycosis and the increasing number of cases reported during the COVID-19 pandemic, prosthodontists need to share their experiences with prosthetic rehabilitation of the defects that result from this disease to improve patients' quality of life.

Case Report: Dental treatment for an oboist: Post-trauma prosthetic rehabilitation and evaluation of musical performance.

Introduction: The condition of teeth and function of the oral organs are important when playing wind or brass instruments. Although there are some reports on dental treatment for musicians, few studies have investigated their acoustic performance following treatment. This report describes the prosthodontic rehabilitation provided for an oboist who had lost a tooth as a result of trauma and includes an evaluation of her subsequent musical performance using acoustic analyzes. Case description: The patient was a 63-year-old professional oboe player who fractured the upper and lower alveolar bone and avulsed the upper right central incisor during a fall due to epileptic seizure. While the alveolar fracture was healing, she sought maxillofacial rehabilitation for the missing tooth to maintain her ability to play the oboe. Her rehabilitation consisted of a provisional removable prosthesis with an acrylic base and clasps followed by a fixed implant prosthesis. A recording of her musical performance was objectively analyzed at each stage of treatment. Rhythm analysis confirmed the stability of notes played rapidly. Her performance dynamics were analyzed by psychoacoustic measurements. Her satisfaction with the prosthesis was assessed by a self-reported questionnaire. The results of the acoustic evaluation helped to adjust the provisional prosthesis so that it was suitable for playing the oboe and the final prosthesis was designed accordingly. Conclusion: Prosthetic dental treatment for this patient included both subjective and objective evaluations that helped to ensure that she could continue playing the oboe at her previous performance level.