RESUMEN
The aim of this study is to present an unusual site of renal cell carcinoma metastasis. A 60-year old man presented to our clinic with massive rectal bleeding. A large small intestine metastasis from renal cell carcinoma was evidenced by an elective angiography of the superior mesenteric artery. This metastasis was surgically excised.
Asunto(s)
Carcinoma de Células Renales/complicaciones , Hemorragia Gastrointestinal/etiología , Neoplasias Intestinales/complicaciones , Neoplasias Renales/complicaciones , Angiografía/métodos , Carcinoma de Células Renales/secundario , Carcinoma de Células Renales/cirugía , Procedimientos Quirúrgicos del Sistema Digestivo/métodos , Hemorragia Gastrointestinal/diagnóstico por imagen , Humanos , Neoplasias Intestinales/secundario , Neoplasias Intestinales/cirugía , Neoplasias Renales/patología , Neoplasias Renales/cirugía , Masculino , Persona de Mediana EdadRESUMEN
AIMS: To report a case of pyothorax-associated lymphoma in a non-immunocompromised 78-year-old man with a 45-year history of tuberculous pleuritis and left pleural effusion. Pyothorax-associated lymphoma is a high-grade non-Hodgkin's lymphoma occurring in 2% of patients with long-standing tuberculous pleuritis and pyothorax. Pyothorax-associated lymphoma is frequently Epstein-Barr virus (EBV)-associated, mainly reported in Japan but exceedingly rare in western countries. METHODS AND RESULTS: Histology revealed a high-grade, diffuse large B-cell lymphoma with immunoblastic and plasmacytoid features and marked angiocentricity with focal destruction of the vessel walls. Immunohistochemistry revealed a post germinal B-cell phenotype. RNA in-situ hybridization and molecular analysis showed a latent EBV infection and absence of human herpes virus-8 (HHV-8). CONCLUSIONS: Pyothorax-associated lymphoma represents a rare but distinctive type of diffuse large B-cell lymphoma, with characteristic clinico-epidemiological, immunohistological, and biological features.
