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1.
J Biol Rhythms ; 39(1): 79-99, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-37786272

RESUMEN

This study examines population-level daily patterns of time-stamped emergency medical service (EMS) dispatches to establish their situational predictability. Using visualization, sinusoidal regression, and statistical tests to compare empirical cumulative distributions, we analyzed 311,848,450 emergency medical call records from the US National Emergency Medical Services Information System (NEMSIS) for years 2010 through 2022. The analysis revealed a robust daily pattern in the hourly distribution of distress calls across 33 major categories of medical emergency dispatch types. Sinusoidal regression coefficients for all types were statistically significant, mostly at the p < 0.0001 level. The coefficient of determination (R2) ranged from 0.84 and 0.99 for all models, with most falling in the 0.94 to 0.99 range. The common sinusoidal pattern, peaking in mid-afternoon, demonstrates that all major categories of medical emergency dispatch types appear to be influenced by an underlying daily rhythm that is aligned with daylight hours and common sleep/wake cycles. A comparison of results with previous landmark studies revealed new and contrasting EMS patterns for several long-established peak occurrence hours-specifically for chest pain, heart problems, stroke, convulsions and seizures, and sudden cardiac arrest/death. Upon closer examination, we also found that heart attacks, diagnosed by paramedics in the field via 12-lead cardiac monitoring, followed the identified common daily pattern of a mid-afternoon peak, departing from prior generally accepted morning tendencies. Extended analysis revealed that the normative pattern prevailed across the NEMSIS data when reorganized to consider monthly, seasonal, daylight-savings versus civil time, and pre-/post-COVID-19 periods. The predictable daily EMS patterns provide impetus for more research that links daily variation with causal risk and protective factors. Our methods are straightforward and presented with detail to provide accessible and replicable implementation for researchers and practitioners.


Asunto(s)
Ritmo Circadiano , Servicios Médicos de Urgencia , Estudios Retrospectivos
2.
Appl Netw Sci ; 3(1): 7, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30839803

RESUMEN

We describe a methodology for characterizing the relative structural importance of an arbitrary network edge by exploiting the properties of a k-shortest path algorithm. We introduce the metric Edge Gravity, measuring how often an edge occurs in any possible network path, as well as k-Gravity, a lower bound based on paths enumerated while solving the k-shortest path problem. The methodology is demonstrated using Granovetter's original strength of weak ties network examples as well as the well-known Florentine families of the Italian Renaissance and the Krebs 2001 terrorist networks. The relationship to edge betweenness is established. It is shown that important edges, i.e. ones with a high Edge Gravity, are not necessarily adjacent to nodes of importance as identified by standard centrality metrics, and that key nodes, i.e. ones with high centrality, often have their importance bolstered by being adjacent to bridges to nowhere-e.g. ones with low Edge Gravity. It is also demonstrated that Edge Gravity distinguishes critically important bridges or local bridges from those of lesser structural importance.

3.
J Food Prot ; 77(12): 2181-8, 2014 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-25474070

RESUMEN

We propose a methodological framework for managing mycotoxin risks in the food processing industry. Mycotoxin contamination is a well-known threat to public health that has economic significance for the food processing industry; it is imperative to address mycotoxin risks holistically, at all points in the procurement, processing, and distribution pipeline, by tracking the relevant data, adopting best practices, and providing suitable adaptive controls. The proposed framework includes (i) an information and data repository, (ii) a collaborative infrastructure with analysis and simulation tools, (iii) standardized testing and acceptance sampling procedures, and (iv) processes that link the risk assessments and testing results to the sourcing, production, and product release steps. The implementation of suitable acceptance sampling protocols for mycotoxin testing is considered in some detail.


Asunto(s)
Contaminación de Alimentos/análisis , Contaminación de Alimentos/prevención & control , Micotoxinas/análisis , Industria de Alimentos , Microbiología de Alimentos , Salud Pública , Medición de Riesgo
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