Depleted iron stores without anaemia early in pregnancy carries increased risk of lower birthweight even when supplemented daily with moderate iron.

BACKGROUND: Gestational iron-deficiency anaemia has adverse pregnancy outcomes. Antenatal iron supplementation can be beneficial in anaemic women, but the effects in non-anaemic women are controversial. This observational study assessed the relationship of maternal iron stores (depleted or non-depleted) at gestational Weeks 8-12 with birthweight, in non-anaemic pregnant women following the guidelines of the Ministry of Health of Spain. METHODS: Healthy, non-anaemic pregnant women (n = 205) were studied. At the first antenatal visit, a general clinical assessment was conducted, and basal blood taken. Women were classified as having non-depleted or depleted iron stores [serum ferritin (SF) < 12 µg/l)]. Daily antenatal iron supplements (48 mg on average) were started at 17 (range: 16-18) weeks. Blood haemoglobin, SF and transferrin saturation (TS) were measured in each trimester. RESULTS: Of the study sample, 20, 54 and 66% had SF < 12 µg/l in the first, second and third trimesters, respectively. The prevalence of iron-depletion (SF < 12 µg/l) and iron-deficiency (SF < 12 µg/l and TS < 16%) was greater during the entire pregnancy in women with initial iron depletion versus no depletion (81.6 and 73.7% versus 61.7 and 55.4%, respectively, in the third trimester, P < 0.05). Women with initial iron-depletion delivered babies weighing on average 192 g less than that with initial iron stores, after adjusting for confounding variables (P = 0.028). CONCLUSIONS: Beginning pregnancy with non-depleted iron stores is beneficial for the maternal iron status during pregnancy and infant birthweight. These findings reaffirm the importance of health promotion to ensure that women have adequate iron stores prior to, or early in, pregnancy when supplemented with moderate daily iron doses.

Parents' perceptions of their neonates and their relation to infant development.

BACKGROUND: Father and mother neonatal perceptions can alter the parents' behaviour towards their child and influence their relationship and, consequently, his/her development. The aim of this study was to examine how mother-father perceptions of their neonates evolve during the first month of life, and whether these perceptions, and the psychological and social characteristics of the mothers are good predictors of infant development. METHODS: Seventy-two mother-father-child triads participated. Maternal personality, including neuroticism, and maternal depression and anxiety symptoms were assessed. Parents' neonatal perceptions and neonatal behaviour were assessed at 3 days and at 1 month post partum and infant development at 4 and 12 months post partum. RESULTS: Parents' initial perceptions were positive, decreased in both parents during the first month and evolved differently according to the child's gender. High maternal neuroticism was related to worse neonatal perceptions, and high father perception was related to better infant development at 12 months. CONCLUSIONS: These results support the contribution of parents' neonatal perception on infant development and may have social implications regarding the role of fathers in the parenting of their children.