Impacto del COVID-19 en pacientes con estenosis aórtica severa: análisis basado en inteligencia artificial / The impact of COVID-19 in patients with severe aortic stenosis: Artificial intelligence research

Introducción: La estenosis aórtica severa es una enfermedad mortal en caso de no ser intervenida. Este estudio pretende conocer el impacto de la pandemia por COVID-19 en la mortalidad de pacientes con estenosis severa durante la primera ola y compararlo con el mismo período del año anterior. Métodos: Se analizaron mediante software basado en inteligencia artificial todos los pacientes que acudieron al hospital en una región española durante la primera ola y en el año anterior, evaluándose la mortalidad comparada entre pacientes con estenosis aórtica severa con y sin COVID-19 durante la pandemia y la era pre-COVID. Se comparó la mortalidad en tres grupos diferentes. En cuanto al número de cirugías cardiacas, se observó una tendencia a la baja en los pacientes sin COVID-19 con respecto al mismo período del año anterior (p = 0,07), y un descenso significativo entre pacientes COVID-19 positivo y COVID-19 negativo. Resultados: Durante la primera ola, acudieron un 13,82% menos de pacientes. Un total de 1.112 tenían estenosis aórtica, de los cuales un 5,48% fueron COVID-19 positivo. La mortalidad fue mayor (p=0,01) en COVID-19 negativo durante la pandemia (4,37%) frente a los de la era pre-COVID-19 (2,57%); también lo fue en el grupo COVID-19 positivo (11,47%) frente a los COVID-19 negativo (4,37%) durante la primera ola (p=0,01). Se observó una tendencia a la disminución de cirugías (p=0,07) en los pacientes COVID-19 negativo durante la pandemia y disminuyeron significativamente en pacientes COVID-19 positivo, frente a los COVID-19 negativo (p=0,04). Conclusiones: El estudio reveló una disminución de los pacientes que acudieron al hospital y un exceso de mortalidad en pacientes con estenosis aórtica severa sin la infección durante la primera ola, frente al mismo período del año anterior; y también, en los pacientes COVID-19 positivo, frente a los COVID-19 negativo. (AU)

Introduction: Untreated, severe, symptomatic aortic stenosis is associated with an ominous diagnosis without intervention. This study aims to determine the impact of the COVID-19 pandemic on the mortality of patients with severe stenosis during the first wave and compare it with the same period last year. Methods: All patients who went to the hospitals in an Spanish region during the first wave, and in the same period of previous year, were analyzed using artificial intelligence-based software, evaluating the mortality of patients with severe aortic stenosis with and without COVID-19 during the pandemic and the pre-COVID era. Mortality of the 3 groups was compared. Regarding cardiac surgeries was a tendency to decrease (P=.07) in patients without COVID-19 between the pandemic and the previous period was observed. A significant decrease of surgeries between patients with COVID-19 and without COVID-19 was shown. Results: Data showed 13.82% less admitted patients during the first wave. A total of 1,112 of them had aortic stenosis and 5.48% were COVID-19 positive. Mortality was higher (P=.01), in COVID-19 negative during the pandemic (4.37%) versus those in the pre-COVID-19 era (2.57%); it was also in the COVID-19 positive group (11.47%), versus COVID-19 negative (4.37%) during the first wave (P=.01). Conclusions: The study revealed a decrease in patients who went to the hospital and an excess of mortality in patients with severe aortic stenosis without infection during the first wave, compared to the same period last year; and also, in COVID-19 positive patients versus COVID-19 negative. (AU)

The impact of COVID-19 in patients with severe aortic stenosis: Artificial intelligence research.

INTRODUCTION: Untreated, severe, symptomatic aortic stenosis is associated with an ominous diagnosis without intervention. This study aims to determine the impact of the COVID-19 pandemic on the mortality of patients with severe stenosis during the first wave and compare it with the same period last year. METHODS: All patients who went to the hospitals in a spanish region during the first wave, and in the same period of previous year, were analysed using Artificial Intelligence-based software, evaluating the mortality of patients with severe aortic stenosis with and without COVID-19 during the pandemic and the pre-COVID era. Mortality of the three groups were compared. Regarding cardiac surgeries was a tendency to decrease (p = .07) in patients without COVID-19 between the pandemic and the previous period was observed. A significant decrease of surgeries between patients with COVID-19 and without COVID-19 was shown. RESULTS: Data showed 13.82% less admitted patients during the first wave. 1112 of them, had aortic stenosis and 5.48% were COVID-19 positive. Mortality was higher (p = .01), in COVID-19 negative during the pandemic (4.37%) versus those in the pre-COVID19 era (2.57%); it was also in the COVID-19 positive group (11.47%), versus covid-19 negative (4.37%) during the first wave (p = .01). CONCLUSIONS: The study revealed a decrease in patients who went to the hospital and an excess of mortality in patients with severe AD without infection during the first wave, compared to the same period last year; and also, in COVID-19 positive patients versus COVID-19 negative.

[The impact of COVID-19 in patients with severe aortic stenosis: Artificial intelligence research]. / Impacto del COVID-19 en pacientes con estenosis aórtica severa: análisis basado en inteligencia artificial.

Introduction: Untreated, severe, symptomatic aortic stenosis is associated with an ominous diagnosis without intervention. This study aims to determine the impact of the COVID-19 pandemic on the mortality of patients with severe stenosis during the first wave and compare it with the same period last year. Methods: All patients who went to the hospitals in an Spanish region during the first wave, and in the same period of previous year, were analyzed using artificial intelligence-based software, evaluating the mortality of patients with severe aortic stenosis with and without COVID-19 during the pandemic and the pre-COVID era. Mortality of the 3 groups was compared. Regarding cardiac surgeries was a tendency to decrease (P = .07) in patients without COVID-19 between the pandemic and the previous period was observed. A significant decrease of surgeries between patients with COVID-19 and without COVID-19 was shown. Results: Data showed 13.82% less admitted patients during the first wave. A total of 1,112 of them had aortic stenosis and 5.48% were COVID-19 positive. Mortality was higher (P = .01), in COVID-19 negative during the pandemic (4.37%) versus those in the pre-COVID-19 era (2.57%); it was also in the COVID-19 positive group (11.47%), versus COVID-19 negative (4.37%) during the first wave (P = .01). Conclusions: The study revealed a decrease in patients who went to the hospital and an excess of mortality in patients with severe aortic stenosis without infection during the first wave, compared to the same period last year; and also, in COVID-19 positive patients versus COVID-19 negative.