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1.
Gerontologist ; 62(2): 212-222, 2022 Feb 09.
Artículo en Inglés | MEDLINE | ID: mdl-34015135

RESUMEN

BACKGROUND AND OBJECTIVES: Intimate partner violence (IPV) has been linked with poor health among young transgender adults, and cisgender lesbian, gay, bisexual (LGB), and heterosexual adults aged 50 years and older. The objective was to examine lifetime prevalence of IPV and its association with health, among transgender adults aged 50 and older. Consistent with the Gender Minority Stress Framework, any IPV was hypothesized to be associated with worse health. RESEARCH DESIGN AND METHODS: Responses from 3,462, transgender adults aged 50 and older from the 2015 U.S. Transgender Survey were assessed for lifetime IPV and type. Logistic regression analyses, adjusted for demographic characteristics, examined the association between any IPV and substance use, and mental and general health measures. RESULTS: 57% of respondents reported any lifetime IPV, including transgender-specific (41%), physical (36%), psychological (29%), severe physical (24%), stalking (12%), and sexual (10%) abuse. Given any, compared to no, experience of IPV, the odds of having a disability (adjusted odds ratio [AOR] = 1.21, confidence interval [CI] = 1.00-1.46) and rating current health more negatively (AOR = 1.17, CI = 1.08-1.26); smoking (AOR = 1.31, CI = 1.08-1.58) and qualifying for screening for serious mental illness (AOR = 1.32, CI = 1.04-1.66) within the last month; and ever using drugs (AOR = 1.42, CI = 1.22-1.65) and attempting suicide (AOR = 1.98, CI = 1.66-2.46) were significantly higher; only binge drinking was unrelated to IPV. DISCUSSION AND IMPLICATIONS: More than half of the respondents experienced IPV, with trans-specific IPV reported most commonly. Lifetime prevalence of any IPV was significantly associated with worse health. Recommendations include health surveillance that recognizes gender identity, and longitudinal study and routine screening of IPV, including trans-specific abuse, among transgender adults aged 50 and older.


Asunto(s)
Violencia de Pareja , Personas Transgénero , Anciano , Femenino , Identidad de Género , Humanos , Estudios Longitudinales , Masculino , Persona de Mediana Edad , Prevalencia , Factores de Riesgo , Personas Transgénero/psicología
2.
J Autism Dev Disord ; 49(1): 260-269, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-30267251

RESUMEN

We know little about custodial grandparents of children with autism spectrum disorder (ASD) who offer a vital social safety net. 117 custodial grandparents of children with ASD from 37 states completed an online survey with open-ended questions about their "greatest challenges and joys" as grandparent. Grounded theory analysis revealed four categories of experience (Issues with Adult Children, Caregiving Burden, Coping, & Wisdom) explained by 15 themes. Grandparents' stressors encompassed custody issues, ASD problem behaviors like tantrums and eloping, insufficient ASD services, financial burden, 24/7 caregiving demands, social isolation, and fears for the future. Grandparents' coping included celebrations of progress, unconditional love, faith, and a positive focus. Grandparents' wisdom included patience and insight. Recommendations to support these caregivers are provided.


Asunto(s)
Trastorno del Espectro Autista/psicología , Cuidadores/psicología , Abuelos/psicología , Adaptación Psicológica , Anciano , Niño , Femenino , Humanos , Masculino , Persona de Mediana Edad
3.
J Autism Dev Disord ; 47(10): 2957-2968, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28688077

RESUMEN

Limited information is available regarding the first person perspective of grandparents of children with Autism Spectrum Disorders (ASD). In the present study, 1870 grandparents of a child with ASD participated in a nationwide, online, anonymous, 30-minute survey and responded to open-ended questions including their "greatest challenges and greatest joys" as the grandparent of a child on the autism spectrum. A grounded theory approach to qualitative analysis revealed four overarching categories: a Desire for Connection, Barriers to Care, Celebration of Progress, and Personal Reactions. Despite the presence of significant challenges grandparents often experienced positivity in their role, and engaged in radical acceptance of their grandchild as well as transformative insight and advocacy. Specific recommendations are offered to help address grandparents' needs and capitalize upon their resilience.


Asunto(s)
Trastorno del Espectro Autista/psicología , Abuelos/psicología , Necesidades y Demandas de Servicios de Salud , Anciano , Niño , Femenino , Teoría Fundamentada , Humanos , Relaciones Intergeneracionales , Masculino , Persona de Mediana Edad , Investigación Cualitativa , Encuestas y Cuestionarios
4.
Clin Gerontol ; 40(1): 43-50, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28452627

RESUMEN

More than two million Americans live in nursing homes and other long-term care facilities. Available research suggests that the majority of older nursing home residents, including those with some degree of cognitive impairment, place significant value upon a variety of sexual activities. With nearly half of all residents suffering from dementia, psychologists and other mental health professionals often face significant challenges in the assessment of their patients' sexual consent capacity. A primary ethical issue is to balance an individual resident's rights to autonomy and privacy with a facility's need to protect residents from harm. Sexual consent capacity functions on a continuum across time and behavior. It also cannot be predetermined by proxy, in which an individual prepares legal documents ahead of time to identify a surrogate decision maker; sexual consent capacity must be determined by information obtained in the present moment. In this paper, an approach to the assessment of residents' sexual consent capacity, encompassing knowledge, reasoning, and voluntariness, along with a brief overview of sexual activity among long-term care residents, will be presented. A case example is offered to illustrate complex clinical dilemmas involving staff attitudes, residents' rights, and family dynamics.


Asunto(s)
Hogares para Ancianos/ética , Competencia Mental , Casas de Salud/ética , Conducta Sexual/ética , Anciano , Toma de Decisiones , Familia/psicología , Femenino , Evaluación Geriátrica , Humanos , Masculino , Autonomía Personal , Conducta Sexual/psicología
5.
Appetite ; 105: 298-305, 2016 10 01.
Artículo en Inglés | MEDLINE | ID: mdl-27263068

RESUMEN

Restrictive eating disorders (ED) are increasing and represent a serious risk to the health of adolescent females. Restrictive ED in youth are often treated through aggressive short-term refeeding. Although evidence supports that this intervention is the "gold standard" for improving ED outcomes in youth, little research has specifically probed appetite and meal-related responses to this type of intensive, short-term refeeding in newly diagnosed individuals. Information about appetite and meal-related dysfunction could provide valuable insights regarding treatment-interfering features of ED in both acute inpatient and longer-term outpatient treatment. The purpose of this study was to evaluate the hunger, fullness, olfactory, and gustatory responses of adolescents with newly-diagnosed restrictive ED and to probe how and when these responses are altered by refeeding. Using a quasi-experimental ecologically valid methodology, this study described and compared profiles of hunger, fullness, olfactory, and gustatory responses in adolescent females (n = 15) with newly diagnosed restrictive ED at hospital admission (i.e., severe malnutrition) and after medical refeeding, in comparison to healthy controls (n = 15). Results showed that newly diagnosed (i.e., malnourished) adolescents with ED showed significantly different meal-related experiences than controls. Refeeding improved some of these differences, but not all. Following refeeding, females with ED continued to show lower hunger, greater fullness, and lower pleasantness of smell ratings compared to controls. Unpleasantness of taste ratings maladaptively increased, such that females who were re-fed reported more aversive scents than pre-treatment. Profiles of meal-related responses were also identified and compared between groups. The applicability of these findings are discussed within the context of critical periods of change during refeeding treatment and potentially promising intervention targets that might enhance treatment outcomes for adolescents with newly onset, restrictive ED.


Asunto(s)
Fenómenos Fisiológicos Nutricionales de los Adolescentes , Regulación del Apetito , Trastornos de Alimentación y de la Ingestión de Alimentos/dietoterapia , Comidas , Respuesta de Saciedad , Adolescente , Adulto , Anorexia Nerviosa/dietoterapia , Anorexia Nerviosa/fisiopatología , Anorexia Nerviosa/psicología , Índice de Masa Corporal , Desayuno/psicología , Trastornos de Alimentación y de la Ingestión de Alimentos/fisiopatología , Trastornos de Alimentación y de la Ingestión de Alimentos/psicología , Femenino , Hospitales Pediátricos , Humanos , Hambre , Comidas/psicología , Odorantes , Ohio , Placer , Escalas de Valoración Psiquiátrica , Desnutrición Aguda Severa/etiología , Desnutrición Aguda Severa/prevención & control , Índice de Severidad de la Enfermedad , Delgadez/dietoterapia , Delgadez/psicología , Aumento de Peso , Adulto Joven
6.
Child Health Care ; 44(1): 17-39, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-25750471

RESUMEN

This longitudinal study examines links among adolescent internalizing and externalizing symptoms, the prenatal environment (e.g., nicotine exposure) and pre/perinatal maternal health, and cardiovascular risk factors. Girls (N=262) ages 11-17 reported internalizing and externalizing behaviors and mothers reported about the prenatal environment and maternal health during and 3 months post-pregnancy. Adolescent cardiovascular risk included adiposity, smoking, blood pressure, and salivary C-reactive protein. Internalizing symptoms mediated relations between prenatal exposures/maternal health and adiposity; externalizing symptoms mediated relations between prenatal exposures and adolescent smoking. Healthcare providers who attend to internalizing and externalizing symptoms in girls may ultimately influence cardiovascular health, especially among those with pre/perinatal risk factors.

7.
Psychosom Med ; 76(7): 547-54, 2014 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-25170752

RESUMEN

OBJECTIVE: This study examined the association between depressive and menstrual symptoms in adolescent girls in a 3-year longitudinal study. It was hypothesized that menstrual symptoms would increase in early adolescence and decrease in later adolescence, that girls with greater depressive symptoms would report greater menstrual symptoms, and that effects would persist after adjusting for general somatic complaints. METHODS: A community sample of girls (n = 262) enrolled in an observational study by age cohort (11, 13, 15, 17 years) completed three annual visits. At each time point, girls completed the Menstrual Symptom Questionnaire, Children's Depression Inventory, and the Youth Self Report to assess general somatic complaints. RESULTS: Menstrual symptoms increased significantly across adolescence (p = .006) and began to plateau in later adolescence (p = .020). Depressive symptoms at study entry were significantly associated with menstrual symptoms (p < .001). When general somatic complaints were included in the models, the effect of depressive symptoms on menstrual symptoms remained significant for the sum score (p = .015) and the menstrual somatic symptoms subscale (p = .001). After adjusting for somatic complaints, initial report of depressive symptoms predicted change in menstrual symptoms only for girls with the lowest menstrual symptoms sum score (p = .025). Initial report of somatic complaints predicted change in menstrual symptoms (p = .020). CONCLUSIONS: Girls with higher depressive symptoms and higher somatic complaints are at greater risk for experiencing menstrual symptoms and increasing symptoms across adolescence, with a heightened vulnerability for girls with lower baseline menstrual symptoms.


Asunto(s)
Depresión/complicaciones , Dismenorrea/psicología , Adolescente , Factores de Edad , Niño , Depresión/psicología , Dismenorrea/complicaciones , Femenino , Humanos , Estudios Longitudinales , Escalas de Valoración Psiquiátrica , Factores de Riesgo , Encuestas y Cuestionarios
8.
J Clin Endocrinol Metab ; 99(5): E841-7, 2014 May.
Artículo en Inglés | MEDLINE | ID: mdl-24512495

RESUMEN

CONTEXT: Women with polycystic ovary syndrome (PCOS) have a high prevalence of cardiovascular disease (CVD) risk factors including dyslipidemia. Lipoproteins are heterogeneous, and measurement of serum lipids provides only the size of the pool and does not predict their function or composition. Recently, high-density lipoprotein cholesterol (HDL-C) function, as determined by cholesterol efflux capacity from macrophages, has been shown to be an independent predictor of subclinical CVD. OBJECTIVE: The aim of the study was to comprehensively evaluate lipoprotein profile including lipid particle size and number and cholesterol efflux capacity in PCOS to better define CVD risk. DESIGN AND SETTING: A case control study was performed at an academic PCOS center. PATIENTS: Women with PCOS (n = 124) and geographically matched controls (n = 67) were included in the study. MAIN OUTCOME MEASURES: The primary outcome was to measure HDL-C efflux capacity by an ex vivo system involving the incubation of macrophages with apolipoprotein (Apo) B-depleted serum from subjects, and the secondary outcome was to measure lipid particle size and number using nuclear magnetic resonance spectroscopy. RESULTS: Women with PCOS had significantly higher body mass index and blood pressure but similar HDL-C and low-density lipoprotein cholesterol levels compared to controls. The mean ApoA1 levels were lower, and the ApoB/ApoA1 ratio was higher in PCOS subjects compared to controls (P < .01). There were no differences in ApoB levels. Women with PCOS had an 7% decrease in normalized cholesterol efflux capacity compared to controls (P < .003). Cholesterol efflux capacity in PCOS correlated with body mass index, ApoA1, HDL-C, and the presence of metabolic syndrome. In a multivariable regression model, PCOS was significantly associated with diminished cholesterol efflux. PCOS was also associated with an atherogenic profile including an increase in large very low-density lipoprotein particles, very low-density lipoprotein (VLDL) size, and small low-density lipoprotein cholesterol particles (P < .01). CONCLUSIONS: Our novel findings of decreased cholesterol efflux and an atherogenic lipid particle number and size pattern in women with PCOS, independent of obesity, further substantiate the increased risk of CVD in this population.


Asunto(s)
Aterosclerosis/sangre , Colesterol/sangre , Dislipidemias/sangre , Lípidos/sangre , Síndrome del Ovario Poliquístico/sangre , Adolescente , Adulto , Aterosclerosis/complicaciones , Estudios de Casos y Controles , HDL-Colesterol/sangre , LDL-Colesterol/sangre , Dislipidemias/complicaciones , Femenino , Humanos , Persona de Mediana Edad , Síndrome del Ovario Poliquístico/complicaciones
9.
Fertil Steril ; 101(2): 530-5, 2014 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-24382375

RESUMEN

OBJECTIVE: To determine the prevalence of metabolic syndrome (MetSyn) and Framingham cardiovascular disease (CVD) risk in white and black adolescents and adult women with polycystic ovary syndrome (PCOS) compared with controls. DESIGN: Retrospective cohort study. SETTING: Center for PCOS. PATIENT(S): Subjects with PCOS with data on race and cardiometabolic risk (n = 519). Controls were age and race matched from the National Health and Nutrition Examination Survey (NHANES) population (1999-2006). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): MetSyn, coronary heart disease risk, and general CVD risk. RESULT(S): Black adolescents and young adults with PCOS had an increased prevalence of MetSyn compared with their white counterparts (adolescents relative risk 2.65 [95% confidence interval 1.29-5.4], adults relative risk 1.44 [95% confidence interval 1.21-2.6]). In contrast, there was no difference in risk of MetSyn between black and white adolescents and adult women in the NHANES dataset. After controlling for age and body mass index, black women with PCOS had a significantly increased prevalence of low high-density lipoprotein and high glucose. The general CVD risk was significantly increased in black adults with PCOS. CONCLUSION(S): This is the first study to comprehensively demonstrate increased risk of MetSyn in both black adolescents and adult women with PCOS compared with white subjects with PCOS. This racial disparity was not present in the NHANES controls. Longitudinal studies are needed to assess the independent impact of PCOS and race on CVD risk in women.


Asunto(s)
Negro o Afroamericano/etnología , Enfermedades Cardiovasculares/etnología , Síndrome Metabólico/etnología , Síndrome del Ovario Poliquístico/etnología , Población Blanca/etnología , Adolescente , Adulto , Enfermedades Cardiovasculares/diagnóstico , Niño , Estudios Transversales , Femenino , Humanos , Síndrome Metabólico/diagnóstico , Persona de Mediana Edad , Síndrome del Ovario Poliquístico/diagnóstico , Estudios Retrospectivos , Factores de Riesgo , Adulto Joven
10.
J Pediatr Adolesc Gynecol ; 26(4): 234-8, 2013 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-23726135

RESUMEN

STUDY OBJECTIVE: Evaluate for differences in the management of adolescents with polycystic ovarian syndrome (PCOS) across 3 pediatric specialties. DESIGN: Retrospective review of medical records. SETTING: Academic children's hospital. PARTICIPANTS: 181 adolescents seen between July 2008 and June 2010 by providers in Pediatric Endocrinology (PEndo), Adolescent Medicine (AMed), or Pediatric and Adolescent Gynecology (PGyn) identified via billing data (ICD-9 code for PCOS, 256.4). INTERVENTIONS: None. MAIN OUTCOME MEASURES: (1) Percentage of adolescents with a billing diagnosis of PCOS who met diagnostic criteria; (2) Percentage of individuals screened for comorbidities and differences across specialties; (3) Differences in treatment recommendations across specialties; (4) Factors associated with recommendation for metformin and hormonal contraceptives. RESULTS: Thirteen percent of PEndo patients did not meet diagnostic criteria for PCOS; 20% of AMed and PGyn patients did not meet criteria. There were significant differences in rates of screening for obesity, insulin resistance, and Type 2 diabetes. There were significant differences in treatment recommendations for lifestyle changes, metformin, and anti-androgen therapy across specialties. Specialty and obesity were significant predictors of metformin recommendation; specifically PEndo predicted metformin recommendation. PGyn and AMed specialties predicted hormonal contraceptive recommendation. CONCLUSIONS: The variability observed among specialties may be due to differences in training, accounting for a range of comfort with aspects of PCOS. Formulation of consensus guidelines for diagnosis and management of PCOS are needed, along with broad educational efforts. By correctly diagnosing, screening for comorbidities, and managing PCOS appropriately during adolescence, providers may reduce the risk for long-term consequences.


Asunto(s)
Síndrome del Ovario Poliquístico/terapia , Pautas de la Práctica en Medicina , Adolescente , Medicina del Adolescente , Antagonistas de Andrógenos/uso terapéutico , Anticonceptivos Hormonales Orales/uso terapéutico , Diabetes Mellitus Tipo 2/complicaciones , Diabetes Mellitus Tipo 2/diagnóstico , Diabetes Mellitus Tipo 2/tratamiento farmacológico , Endocrinología , Femenino , Ginecología , Humanos , Hipoglucemiantes/uso terapéutico , Resistencia a la Insulina , Estilo de Vida , Metformina/uso terapéutico , Obesidad/complicaciones , Obesidad/diagnóstico , Síndrome del Ovario Poliquístico/complicaciones , Estudios Retrospectivos
11.
J Pediatr Adolesc Gynecol ; 26(1): 47-50, 2013 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-23158754

RESUMEN

STUDY OBJECTIVE: To examine whether the known association between early pubertal breast maturation and insulin sensitivity (SI) is mediated by adiposity. DESIGN: Cross-sectional analyses. SETTING: Observational study examining the roles of environment, diet, and obesity on puberty. PARTICIPANTS: 379 girls with a mean age, 7.03 years; 62% were white and 29% black. MAIN OUTCOME MEASURES: Pubertal development was assessed via physical examination and adiposity by body mass index Z score (BMI Z) and waist-to-height ratio. Fasting blood samples were obtained for insulin and glucose concentrations. SI was calculated with the quantitative insulin sensitivity check index (QUICKI). Analysis of variance and Sobel's test was used to assess mediation. RESULTS: Fifty-five girls were pubertal (Tanner 2 breast). Breast maturation was inversely associated with SI (P = .005) and positively associated with BMI Z (P < .001) and waist-to-height ratio (P < .001). The effect of breast maturation on SI was no longer significant (P = .41) after adjusting for the effect of BMI Z, which remained significant (P < .001). Similar results were obtained when waist-to-height ratio replaced BMI Z in the models. Mediation analyses demonstrated that 75% of the association between breast maturation and SI is mediated by adiposity. CONCLUSIONS: In girls, decreased SI during early puberty is largely mediated by total and visceral adiposity.


Asunto(s)
Adiposidad/fisiología , Resistencia a la Insulina/fisiología , Obesidad/fisiopatología , Pubertad Precoz/fisiopatología , Antropometría , Niño , Estudios Transversales , Femenino , Humanos
12.
J Res Adolesc ; 22(2): 381-391, 2012 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-23204809

RESUMEN

Adolescent sexual maturation is staged using Tanner criteria assessed by clinicians, parents, or adolescents. The physiology of sexual maturation is driven by gonadal hormones. We investigate Tanner stage progression as a function of increasing gonadal hormone concentration and compare performances of different raters. Fifty-six boys (mean age, 12.7±1.3 years) and 52 girls (mean age, 12.0±1.6 years) were seen at baseline, 6, and 12 months. Estradiol and testosterone concentrations were determined from 3 morning serum samples and Tanner stage by three different raters (clinician, parent, adolescent). Results confirm that Tanner criteria reflect gonadal hormone concentrations, and clinician rating provides optimal assessment. Detailed insight about the strengths and limitations of different raters is provided, augmenting the scientific understanding of pubertal development.

13.
Metabolism ; 61(3): 341-8, 2012 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-21944263

RESUMEN

Stress and stress-related concomitants, including hypothalamic-pituitary-adrenal (HPA) axis activation, are implicated in obesity and its attendant comorbidities. Little is known about this relationship in adolescents. To begin to address this important knowledge gap, we studied HPA axis activity in 262 healthy adolescent girls aged 11, 13, 15, and 17 years. We hypothesized that obesity would be correlated with increased HPA axis activity and reactivity. Measures of HPA axis activity included 3 blood samples obtained midday (between 1:00 and 2:00 pm) over the course of 40 minutes; overnight urine free cortisol; and cortisol levels 0, 20, and 40 minutes after venipuncture (cortisol reactivity). Measures of adiposity included body mass index (BMI), BMI z score (BMI-Z), percentage body fat, and fat distribution (central adiposity) assessed by dual-energy x-ray absorptiometry. Daytime levels of serum cortisol were inversely associated with BMI-Z and central adiposity (P < .05). The urine free cortisol excretion rate was positively correlated with BMI, BMI-Z, and central adiposity. There was blunting of cortisol response to venipuncture with increasing adiposity. Our results suggest that there may be reduced cortisol levels during the day and increased levels at night with increasing degree of adiposity. This study provides preliminary findings indicating an alteration of the circadian rhythm of cortisol with obesity. We conclude that obesity is associated with altered HPA activity in adolescent girls. The clinical implications of our findings require further investigation.


Asunto(s)
Sistema Hipotálamo-Hipofisario/fisiopatología , Obesidad/fisiopatología , Sistema Hipófiso-Suprarrenal/fisiopatología , Absorciometría de Fotón , Adiposidad/fisiología , Adolescente , Antropometría , Área Bajo la Curva , Composición Corporal/fisiología , Índice de Masa Corporal , Mama/crecimiento & desarrollo , Niño , Femenino , Humanos , Hidrocortisona/sangre , Hidrocortisona/orina , Estudios Longitudinales , Menarquia , Sobrepeso/fisiopatología , Radioinmunoensayo , Factores Socioeconómicos
14.
J Pediatr Gastroenterol Nutr ; 54(1): 125-35, 2012 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-21857247

RESUMEN

Surgical options for the treatment of adolescent obesity have been gaining popularity. Adolescent patients present a particular challenge to clinicians, secondary to age-related issues, revolving around both mental and physical growth. These age-related issues require a unique approach to nutritional intervention for adolescents undergoing bariatric surgery as opposed to standardized approaches for adults. Despite the increasing numbers of adolescents undergoing obesity surgery, evidence-based nutritional guidelines have yet to be published. The goal of this document is to provide the clinician with recommendations on how to assess, educate, nourish, and monitor the adolescent who has undergone obesity surgery. A multidisciplinary panel composed of 3 pediatric gastroenterologists, 1 psychologist, and 3 registered dietitians from the Nutrition Committee for the North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition and National Association of Children's Hospitals and Related Institutions, with experience in nutrition and adolescent weight loss surgery, reviewed the medical literature for evidence-based practice for nutritional strategies for patients undergoing bariatric surgery. In addition to this group, an adolescent medicine physician was consulted for matters related to reproductive health. The present article presents a consensus of recommendations based on a review of the literature. In areas for which there was a lack of evidence to support the recommendations, best-practice guidelines were used. The present article provides the clinician with an overview of the nutritional concerns for adolescent patients undergoing obesity surgery. These guidelines address the preoperative educational pathway, the postoperative diet progression, recognition of disordered eating, guidelines for female reproductive issues, and assistance for the adolescent in a school/college environment.


Asunto(s)
Cirugía Bariátrica , Dieta , Dietética/métodos , Necesidades Nutricionales , Obesidad Mórbida , Adolescente , Consenso , Trastornos de Alimentación y de la Ingestión de Alimentos , Femenino , Educación en Salud , Humanos , América del Norte , Obesidad Mórbida/cirugía , Embarazo , Salud Reproductiva , Sociedades Médicas
15.
J Adolesc Health ; 49(5): 498-504, 2011 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-22018564

RESUMEN

PURPOSE: The purpose of the study was to examine (a) the association between depressive and anxiety symptoms with bone health, (b) the association of smoking or alcohol use with bone health, and, in turn (c) whether the association between depressive and anxiety symptoms with bone health varied by smoking or alcohol use individually or by combined use. Bone health included total body bone mineral content (TB BMC) and bone mineral density (BMD) of the lumbar spine, total hip, and femoral neck. Previously published data have not examined these issues in adolescence, a period when more than 50% of bone mass is accrued. METHODS: An observational study enrolled 262 healthy adolescent girls by age cohort (11, 13, 15, and 17 years). Participants completed questionnaires and interviews on substance use, depressive symptoms, and anxiety. BMC and BMD were measured by dual-energy X-ray absorptiometry. RESULTS: Higher depressive symptoms were associated with lower TB BMC and BMD (total hip, femoral neck). Those with the lowest level of smoking had higher BMD of the hip and femoral neck, whereas no main effect differences were noted by alcohol use. Regular users of both cigarettes and alcohol demonstrated a stronger negative association between depressive symptoms and TB BMC as compared with nonusers/experimental users and regular alcohol users. Findings were parallel for anxiety symptoms. CONCLUSION: Depressive and anxiety symptoms may negatively influence bone health in adolescent girls. Consideration of multiple substances, rather than cigarettes or alcohol separately, may be particularly informative with respect to the association of depression with bone health.


Asunto(s)
Consumo de Bebidas Alcohólicas/epidemiología , Ansiedad/epidemiología , Enfermedades Óseas/epidemiología , Depresión/epidemiología , Fémur/diagnóstico por imagen , Fumar/epidemiología , Absorciometría de Fotón , Adolescente , Conducta del Adolescente , Densidad Ósea , Enfermedades Óseas/diagnóstico por imagen , Comorbilidad , Femenino , Humanos , Vértebras Lumbares/diagnóstico por imagen , Valores de Referencia , Factores de Riesgo
16.
J Adolesc Health ; 49(4): 350-6, 2011 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-21939864

RESUMEN

PURPOSE: To examine separate mediational models linking (a) menarcheal status or (b) pubertal timing to internalizing and externalizing problems through competence. METHOD: This study involved cross-sectional analyses of 262 adolescent girls (age: 11-17 years; mean = 14.93, standard deviation = 2.17) enrolled in a longitudinal study examining the association of psychological functioning and smoking with reproductive and bone health. Measures of menarcheal status (pre/post), pubertal timing (early, on-time, or late), internalizing and externalizing behavior, and perceived competence (parent and adolescent report) were obtained. Structural equation modeling was used for analyses. RESULTS: Perceived competence was found to fully mediate the association between menarcheal status and parent report of internalizing and externalizing problems. For adolescent report, there was a full mediation effect for internalizing problems but a partial mediation effect for externalizing problems. Being menarcheal was related to lower competence, which was in turn related to higher internalizing and externalizing problems. Models including pubertal timing were not significant. CONCLUSIONS: Perceived competence is important in understanding the associations between menarcheal status and internalizing and externalizing problems. Interventions targeting competence, particularly in postmenarcheal girls, may reduce or prevent problem behaviors.


Asunto(s)
Conducta del Adolescente/psicología , Control Interno-Externo , Menarquia/psicología , Competencia Mental/psicología , Adolescente , Conducta del Adolescente/etnología , Agresión/psicología , Análisis de Varianza , Niño , Depresión/psicología , Femenino , Humanos , Estudios Longitudinales , Pruebas Psicológicas , Pubertad/psicología , Fumar , Factores Socioeconómicos
17.
Discov Med ; 11(61): 521-8, 2011 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-21712018

RESUMEN

The discovery of ghrelin and its role in human metabolism has promoted significant research and advances in the study of obesity and other weight-related disorders. Ghrelin is relevant to many disorders of metabolism and weight such as obesity, cachexia, Prader-Willi Syndrome (PWS), and Anorexia Nervosa (AN), and its role in the pathophysiology differs. The changes observed in ghrelin physiology in these disorders shed light on the overall role of ghrelin in human metabolism and growth. The purpose of this review is to summarize the existing literature on ghrelin and some disorders of metabolism and growth. The disorders that will be discussed include obesity, cachexia, PWS, and AN. Within each disorder we will review relevant ghrelin physiology, recent studies, and potential modes of intervention with ghrelin analogues.


Asunto(s)
Peso Corporal/fisiología , Ghrelina/metabolismo , Animales , Anorexia Nerviosa/genética , Anorexia Nerviosa/metabolismo , Peso Corporal/genética , Caquexia/genética , Caquexia/metabolismo , Ghrelina/genética , Humanos , Obesidad/genética , Obesidad/metabolismo , Síndrome de Prader-Willi/genética , Síndrome de Prader-Willi/metabolismo
18.
J Womens Health (Larchmt) ; 20(4): 533-8, 2011 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-21413894

RESUMEN

OBJECTIVE: Adolescent obesity has dramatically increased in recent decades, and along with that so have other medical comorbidities, such as hypertension, diabetes, hyperlipidemia, nonalcoholic steatohepatitis, polycystic ovary syndrome (PCOS), and pseudotumor cerebri. Obesity and related comorbidites may be contraindications to hormonal contraception, making contraception counseling of morbidly obese adolescents more challenging. Obese adolescent females seeking bariatric surgery need effective contraception in the postoperative period. This study is designed to determine the acceptance rate of the levonorgestrel-releasing intrauterine device (IUD) and describe common menstrual problems in obese adolescent bariatric surgery patients. METHODS: This is a historic cohort study of adolescent females who underwent bariatric surgery over a 2-year period at a tertiary referral center for pediatric obesity. Data were systematically abstracted. The percent of patients with menstrual problems and the acceptance rate for the levonorgestrel-releasing IUD were determined. RESULTS: Twenty-five adolescents met inclusion criteria. The mean age was 17.4 years (standard deviation [SD] 2.6), and the mean body mass index (BMI) was 51.4 (SD 6.3) kg/m(2). Eighty-four percent were white. Twenty-eight percent had menorrhagia, 32% had oligomenorrhea, 40% had dysmenorrhea, and 36% had PCOS. Ninety-two percent (23 of 25) underwent IUD placement. CONCLUSIONS: There was a high prevalence of menstrual problems among this sample of severely obese adolescent females. The majority accepted the IUD, indicating it is a viable option among this population.


Asunto(s)
Anticoncepción/psicología , Anticonceptivos Femeninos/uso terapéutico , Dispositivos Intrauterinos Medicados/estadística & datos numéricos , Levonorgestrel/uso terapéutico , Trastornos de la Menstruación/epidemiología , Aceptación de la Atención de Salud/estadística & datos numéricos , Adolescente , Cirugía Bariátrica , Estudios de Cohortes , Anticoncepción/métodos , Anticoncepción/estadística & datos numéricos , Bases de Datos Factuales , Femenino , Humanos , Trastornos de la Menstruación/etiología , Obesidad/complicaciones , Obesidad/psicología , Obesidad/cirugía , Ohio/epidemiología , Adulto Joven
20.
Clin Pediatr (Phila) ; 49(7): 671-7, 2010 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-20356924

RESUMEN

The purpose of this study is to evaluate the association between anxiety and depressive symptoms and obesity among adolescent females using objective measures of adiposity and evaluate for moderating effects of race and age. This is a cross-sectional analysis of 198 females aged 11, 13, 15, and 17 years (mean = 14.6, standard deviation = 2.2). Adiposity measures include BMI, BMI Z score, percentage body fat from dual energy X-ray absorptiometry (DXA), and fat distribution (fat mass upper vs lower body regions from DXA). Symptoms of anxiety are measured with the State-Trait Anxiety Inventory and depressive symptoms with the Children's Depression Inventory. Trait anxiety and depressive symptoms are positively associated with BMI and percentage body fat. No interaction of anxiety/ depressive symptoms with race or age on measures of adiposity was detected. Symptoms of anxiety and depression are associated with percentage body fat among adolescent females, linking psychological distress with a physiological measure of adiposity.


Asunto(s)
Ansiedad/epidemiología , Índice de Masa Corporal , Trastorno Depresivo/epidemiología , Obesidad/diagnóstico , Obesidad/psicología , Absorciometría de Fotón , Adiposidad/fisiología , Adolescente , Conducta del Adolescente , Distribución por Edad , Ansiedad/etiología , Composición Corporal , Niño , Comorbilidad , Estudios Transversales , Trastorno Depresivo/etiología , Femenino , Humanos , Análisis Multivariante , Obesidad/complicaciones , Valores de Referencia , Análisis de Regresión , Medición de Riesgo
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