RESUMEN
NF3 and N(NO2)3 are known compounds, whereas the mixed fluoronitroamines, FN(NO2)2 and F2NNO2, have been unknown thus far. One of these, FN(NO2)2, has now been prepared and characterized by multinuclear NMR and Raman spectroscopy. FN(NO2)2 is the first known example of an inorganic fluoronitroamine. It is a thermally unstable, highly energetic material formed by the fluorination of the dinitramide anion using NF4(+) salts as the preferred fluorinating agent.
RESUMEN
The title salt, (C(2)H(8)NO(3)S)[SbF(6)], which contains the protonated form of taurine (2-aminoethanesulfonic acid), was synthesized in anhydrous hydrofluoric acid and recrystallized as colourless block-shaped crystals from liquid SO(2). In the solid state, a three-dimensional network is observed. This is formed by intra- and intermolecular N-H···O, N-H···F and O-H···F hydrogen bonds.
Asunto(s)
Compuestos Organometálicos/química , Compuestos Organometálicos/síntesis química , Taurina/química , Cristalografía por Rayos X , Enlace de Hidrógeno , Estructura Molecular , Sales (Química)RESUMEN
Imidazolone (dIz) is an abundant, highly mutagenic, and rather unstable DNA lesion that can cause dG-->dC transversion mutations. dIz is generated in DNA by a variety of oxidative processes such as type I photooxidation. Herein we report the synthesis of a carbocyclic nucleoside analogue of dIz and of DNA containing this stabilized lesion analogue. The carbocyclic modification protects this lesion analogue from anomerization. As the repair of the lesion analogue by DNA glycosylases is not possible, this analogue should allow cocrystallization studies together with wild-type repair enzymes. Characterization of the lesion analogue was performed by using spectroscopic methods and enzymatic digestion experiments of the oligonucleotides.