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1.
Tokai J Exp Clin Med ; 49(1): 22-26, 2024 Apr 20.
Artículo en Inglés | MEDLINE | ID: mdl-38509009

RESUMEN

Angiosarcoma is a rare malignant tumor of endothelial origin. It is an aggressive neoplasm with early metastasis and poor prognosis and accounts for approximately 2% of all soft tissue sarcomas. Primary tumors arising in the oral cavity account for only 1% of all angiosarcomas. Here, we report a rare case of metastatic angiosarcoma of the gingiva originating from a primary mediastinal lesion. The patient was an 83-year-old man who presented with a maxillary interincisor tumor; it was a painless mass with rounded superficial necrosis measuring 23 mm× 17 mm on the labial side and 20 mm× 17 mm on the palatal side. The histopathological diagnosis was of an epithelioid angiosarcoma. Imaging revealed lesions in the mediastinum, lungs, liver, and skin. The primary lesion was considered a mediastinal lesion. As the tumor had spread throughout the body, palliative therapy was administered. However, the patient's general condition deteriorated rapidly, and he died 3 weeks after the first visit. Identifying oral metastatic malignancies may result in detection of malignant tumors at other sites; thus, oral and maxillofacial surgeons must maintain a heightened awareness of angiosarcoma.


Asunto(s)
Hemangiosarcoma , Masculino , Humanos , Anciano de 80 o más Años , Hemangiosarcoma/patología , Hemangiosarcoma/terapia , Encía/patología
2.
Tokai J Exp Clin Med ; 45(4): 189-194, 2020 Dec 20.
Artículo en Inglés | MEDLINE | ID: mdl-33300589

RESUMEN

Brain abscesses occur in 0.3-1.3 per 100,000 worldwide each year with 0.4-0.9 in Japan alone. Most of the causes are direct infection from a nearby infectious lesion and are rarely caused by an odontogenic infection. Here, we reported a case of brain abscess suspected to be associated with odontogenic infection. The patient was a 55-year-old woman. Blurred eyes and pain in the left eye noted, for which she consulted an ophthalmologist, but her eyes were normal. She was conscious and was able to converse clearly, but she could not read the letters and had difficulty in writing at the time of admission. A brain abscess was diagnosed based on the head magnetic resonance imaging (MRI) and clinical course, and a small craniotomy abscess drainage was performed. A. cardiffensis and P. micra were detected in the abscess, suggesting the involvement of periodontal disease bacteria. After the surgery, antimicrobial treatment was performed for about 2 months. At the same time, perioperative treatment was performed. On the 70th day after the surgery, tooth extraction, which was considered as the source of infection, was performed. The patient was discharged 74 days after surgery. A good turning point was obtained without relapse of symptoms.


Asunto(s)
Actinomycetaceae , Antibacterianos/administración & dosificación , Infecciones Bacterianas/etiología , Infecciones Bacterianas/microbiología , Absceso Encefálico/etiología , Absceso Encefálico/microbiología , Infecciones Bacterianas del Sistema Nervioso Central/etiología , Infecciones Bacterianas del Sistema Nervioso Central/microbiología , Firmicutes , Periodontitis/complicaciones , Periodontitis/microbiología , Actinomycetaceae/patogenicidad , Infecciones Bacterianas/diagnóstico por imagen , Infecciones Bacterianas/terapia , Absceso Encefálico/diagnóstico por imagen , Absceso Encefálico/terapia , Infecciones Bacterianas del Sistema Nervioso Central/diagnóstico por imagen , Infecciones Bacterianas del Sistema Nervioso Central/terapia , Craneotomía/métodos , Drenaje/métodos , Femenino , Firmicutes/patogenicidad , Humanos , Imagen por Resonancia Magnética , Persona de Mediana Edad , Periodontitis/cirugía , Atención Perioperativa , Tomografía Computarizada por Tomografía de Emisión de Positrones , Extracción Dental , Resultado del Tratamiento
3.
Tokai J Exp Clin Med ; 45(4): 182-188, 2020 Dec 20.
Artículo en Inglés | MEDLINE | ID: mdl-33300588

RESUMEN

Radiation therapy is a frequently used effective treatment for head and neck cancer. It has several adverse effects of which osteomyelitis is a late complication of radiotherapy. Although uncommon, when it occurs in the vertebral body, it results in pyogenic spondylitis, which can be fatal. We report a case of pyogenic spondylitis, observed 2 years and 5 months after chemoradiotherapy following surgery for the treatment of tongue cancer. The initial symptoms were fever and posterior cervical pain. Initial CT images showed no abnormality in the cervical spine. However, when CT and MRI were followed over time, bone destruction and abscess formation were observed at the C3 and C4 vertebral endplates. Hence, CT-guided puncture d rainage was performed from the anterior neck. The collected pus was d iagnosed as Class II pyogenic spondylitis by cytology and the culture test revealed the presence of Streptococcus agalactiae. The infection was successfully treated by drainage and antibacterial chemotherapy.


Asunto(s)
Quimioradioterapia/efectos adversos , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/terapia , Espondilitis/etiología , Espondilitis/terapia , Neoplasias de la Lengua/terapia , Absceso/diagnóstico por imagen , Absceso/etiología , Absceso/microbiología , Absceso/terapia , Adulto , Antibacterianos/uso terapéutico , Vértebras Cervicales/diagnóstico por imagen , Drenaje/métodos , Estudios de Seguimiento , Humanos , Imagen por Resonancia Magnética , Masculino , Complicaciones Posoperatorias/diagnóstico por imagen , Complicaciones Posoperatorias/microbiología , Espondilitis/diagnóstico por imagen , Espondilitis/microbiología , Infecciones Estreptocócicas , Streptococcus agalactiae , Supuración , Tomografía Computarizada por Rayos X , Neoplasias de la Lengua/cirugía , Resultado del Tratamiento
4.
Tokai J Exp Clin Med ; 45(3): 152-155, 2020 Sep 20.
Artículo en Inglés | MEDLINE | ID: mdl-32901906

RESUMEN

BACKGROUND: Temporomandibular joint (TMJ) dislocation can be categorized into three groups: acute, habitual or recurrent, and long-standing. Long-standing TMJ dislocation refers to a condition that persists for more than one month without reduction. Long-standing dislocation of the TMJ is rare and the most challenging and difficult to treat of the three. CASE REPORT: The present case study relates to a 53-year-old woman with long-standing TMJ dislocation of a year's duration who presented for treatment. Due to this condition, she was unable to take food orally, and nutrition was managed by gastrostomy tube feeding. She also suffered from schizophrenia and had been admitted to a closed hospital. Bilateral mandibular condylectomy was performed, restoring oral function. However, post-reduction, an open bite remained, restricting the types of food that she could eat. Additional intermaxillary fixation and intermaxillary traction would have been required for an optimal outcome, but they were not possible for this patient. CONCLUSION: Despite an inability to provide comprehensive treatment, due to patient-related factors, occlusal and masticatory functions were restored to adequate levels following bilateral condylectomy alone. This enabled oral feeding and improved her quality of life.


Asunto(s)
Ingestión de Alimentos , Luxaciones Articulares/cirugía , Cóndilo Mandibular/cirugía , Masticación , Boca/fisiopatología , Recuperación de la Función , Articulación Temporomandibular/cirugía , Femenino , Humanos , Luxaciones Articulares/fisiopatología , Persona de Mediana Edad , Calidad de Vida , Articulación Temporomandibular/fisiopatología , Factores de Tiempo , Resultado del Tratamiento
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