RESUMEN
The use of deoxyribonucleic acid (DNA) hybridization to detect disease-related gene expression is a valuable diagnostic tool. An ion-sensitive field-effect transistor (ISFET) with a graphene layer has been utilized for detecting DNA hybridization. Silicene is a two-dimensional silicon allotrope with structural properties similar to graphene. Thus, it has recently experienced intensive scientific research interest due to its unique electrical, mechanical, and sensing characteristics. In this paper, we proposed an ISFET structure with silicene and electrolyte layers for the label-free detection of DNA hybridization. When DNA hybridization occurs, it changes the ion concentration in the surface layer of the silicene and the pH level of the electrolyte solution. The process also changes the quantum capacitance of the silicene layer and the electrical properties of the ISFET device. The quantum capacitance and the corresponding resonant frequency readout of the silicene and graphene are compared. The performance evaluation found that the changes in quantum capacitance, resonant frequency, and tuning ratio indicate that the sensitivity of silicene is much more effective than graphene.
Asunto(s)
Sondas de ADN , Técnicas Biosensibles , Simulación por Computador , ADN/química , Capacidad Eléctrica , Grafito/química , Silicio/química , Transistores ElectrónicosRESUMEN
This paper contributes a novel design and the corresponding fabrication process to research on the unique topic of micro-electro-mechanical systems (MEMS) deformable convex micromirror used for focusing-power control. In this design, the shape of a thin planar metal-coated polymer-membrane mirror is controlled electromagnetically by using the repulsive force between two magnets, a permanent magnet and a coil solenoid, installed in an actuator system. The 5 mm effective aperture of a large-stroke micromirror showed a maximum center displacement of 30.08 µm, which enabled control of optical power across a wide range that could extend up to around 20 diopters. Specifically, utilizing the maximum optical power of 20 diopter by applying a maximum controlling current of 0.8 A yielded consumption of at most 2 W of electrical power. It was also demonstrated that this micromirror could easily be integrated in miniature tunable optical imaging systems.