1.
J Org Chem
; 89(15): 11019-11025, 2024 Aug 02.
Artículo
en Inglés
| MEDLINE
| ID: mdl-39002159
RESUMEN
The addition of enoxysilanes to vinyl diazonium ions occurs with varying levels of diastereoselectivity. To understand the origins of the stereoselectivity, we studied these transformations using density functional theory (DFT) calculations. The selectivity stems from a stabilizing cation-π interaction that orients the nucleophile and the diazonium ion.