Developing STEM Career Identities among Latinx Youths: Collaborative Design, Evaluations, and Adaptations during COVID-19.

In response to the low representation of Latinx adults in STEM occupations, this community-based participatory action research study aims to increase the number of middle school youths developing STEM career identities and entering high school with the intention to pursue STEM careers. The students were provided with summer and after-school activities focusing on network science and career development curricula. Using a quasi-experimental pretest-posttest design and career narratives, this study examined the changes in STEM and career self-efficacy, as well as career identity. The results show improvements in self-efficacy, an increased number of youths with intentions of pursuing future STEM career opportunities, and deeper reflections on their talents and skills after program participation. This paper also describes the program development and implementation in detail, as well as the adaptations that resulted from COVID-19, for scholars and educators designing similar programs. This study provides promising evidence for the quality of STEM and career development lessons in supporting the emergence of a STEM career identity and self-efficacy.

Personal attributes and attitudes to substance use disorder: A study among Jordanian undergraduate medical majors students.

BACKGROUND: Emerging health professionals in undergraduate programs should be equipped to provide care to people with substance use disorder (SUD). The students' personal attributes may impact their attitude toward those with SUD. This study aims to evaluate the impact of personal attributes of Jordanian undergraduate health students on their attitudes toward SUD and examine the relationship between the personal attributes and their devaluation and discriminatory (stigmatory) behaviour toward those with SUD. METHOD: A cross-sectional descriptive design was used to examine the attitudes and stigmatory behaviours. The data were collected between May to October 2017 with a structured questionnaire that consisted of three parts: 1) a data sheet to collect the socio-demographic characteristics of the participants, 2) the Acute Mental Health Scale (ATAMHS), and 3) the Devaluation-Discrimination Scale (DDS). FINDINGS: Younger and females demonstrated a positive attitude toward those with SUD compared to older or male students. Age, gender, and previous experience with SUD are significant factors that affect their attitude. CONCLUSION: Identifying the attitude to people with SUD and personal attributes of emerging health professionals in Jordan will help identify the need to educate them prior to their entry into practice.

Empowering Women in Finance through Developing Girls' Financial Literacy Skills in the United States.

This study examines the effectiveness of a financial literacy program, Invest in Girls (IIG), in promoting financial capability among high school girls. Using a quasi-experimental separate-samples pretest-posttest design and a longitudinal qualitative study, the study aims to assess the program efficacy and investigate the perspectives of the female students on its impact on their knowledge, behavior, and future goals and aspirations. The results indicated that the participants had significantly higher confidence for engaging in financial literacy after the program. The findings from the longitudinal study also suggested that that the program was influencing the students in positive ways, increasing their financial capability and leading them to consider wide occupational pathways available in finance. Given the lack of female leaders in the world of finance, the IIG program aims to address gender disparity in financial knowledge and highlight the importance of building financial literacy skills among girls.

Psychometric properties of Arabic translated temperament instrument.

BACKGROUND: Investigating temperament has been a multi-subject exercise that attempts to determine the contribution of temperament to additional measurable phenomena like behavior. The existing research not only evaluates temperament as a variable with the ability to influence additional characteristics but has included interventions that can result in adapted outcomes. Develop an Arabic translation of the Infant Characteristics Questionnaire (ICQ). PURPOSE: Examine the psychometric properties of the translation and establish modified criteria for evaluating the questionnaire. METHODS: Cross sectional design was used. Translation of the ICQ was achieved through translation/back translation. The population that used the ICQ translation on convenience sample of 40 Arabic-speaking women with children between the ages of 3-12-months old; this same group also completed a demographic survey. RESULTS: The internal consistency of the translated instrument was almost equivalent to or higher than the reported from the United States (US) review. The alpha coefficients calculated from subscales varied between .47 and .87. CONCLUSION: This research study described the translation of the ICQ into the Arabic language for use in the research and clinical setting. The ICQ is a useful tool for evaluating infant difficulty by describing and summarizing parents' ratings.

Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Homeless Shelters in Chicago, Illinois-March-May, 2020.

BACKGROUND: People experiencing homelessness are at increased risk of coronavirus disease 2019 (COVID-19), but little is known about specific risk factors for infection within homeless shelters. METHODS: We performed widespread severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction testing and collected risk factor information at all homeless shelters in Chicago with at least 1 reported case of COVID-19 (n = 21). Multivariable, mixed-effects log-binomial models were built to estimate adjusted prevalence ratios (aPRs) for SARS-CoV-2 infection for both individual- and facility-level risk factors. RESULTS: During March 1 to May 1, 2020, 1717 shelter residents and staff were tested for SARS-CoV-2; 472 (27%) persons tested positive. Prevalence of infection was higher for residents (431 of 1435, 30%) than for staff (41 of 282, 15%) (prevalence ratio = 2.52; 95% confidence interval [CI], 1.78-3.58). The majority of residents with SARS-CoV-2 infection (293 of 406 with available information about symptoms, 72%) reported no symptoms at the time of specimen collection or within the following 2 weeks. Among residents, sharing a room with a large number of people was associated with increased likelihood of infection (aPR for sharing with >20 people compared with single rooms = 1.76; 95% CI, 1.11-2.80), and current smoking was associated with reduced likelihood of infection (aPR = 0.71; 95% CI, 0.60-0.85). At the facility level, a higher proportion of residents leaving and returning each day was associated with increased prevalence (aPR = 1.08; 95% CI, 1.01-1.16), whereas an increase in the number of private bathrooms was associated with reduced prevalence (aPR for 1 additional private bathroom per 100 people = 0.92; 95% CI, 0.87-0.98). CONCLUSIONS: We identified a high prevalence of SARS-CoV-2 infections in homeless shelters. Reducing the number of residents sharing dormitories might reduce the likelihood of SARS-CoV-2 infection. When community transmission is high, limiting movement of persons experiencing homelessness into and out of shelters might also be beneficial.

Intimidation and bullying: A school survey examining the effect of demographic data.

The aim of this study is to identify the predictors of bullying in secondary school students. This study uses correlational and regression analysis to examine the relationship between demographic data of students and whether or not they partake in bullying or have been bullied. Out of the given surveys, 357 were answered. The survey was given to three public schools from Irbid city. The results of multiple logistic regression tests revealed that level of study (B = .184, p = 0.003) is positively and independently associated with bullying. Factors such as gender, income, and education are not significantly predictive of bullying behavior among school students. This study has implications for healthcare providers, nurses, and policymakers to adapt anti-bullying strategies for all secondary schools.

Correlates and Predictors of Stigmatization of Patients With Mental Illness Among Nursing Students.

The purpose of the current study was to explore knowledge of, attitudes about, and perception of stigma among nursing students in relation to mental illness, and to identify the predictors of stigma toward patients with mental illness based on nursing students' characteristics, knowledge, and attitude. A cross-sectional survey was conducted on 169 participants from a university in Jordan. The regression model predicted a relatively moderate proportion of variance in stigma perception. Significant predictors in the model were family income, father's educational level, and experience with mental health patients. Findings of the current study showed that undergraduate nursing students who had experience with patients with mental illness hold relatively positive perceptions toward mental health patients. Enhancing the content of nursing curriculum regarding issues related to patients with mental illness could help students develop better assessment skills, have more positive attitudes, and gain more accurate knowledge about mental illness. [Journal of Psychosocial Nursing and Mental Health Services, 57(1), 43-51.].

Stress and Depression among Veterinary Medical Students.

While existing literature suggests that professional students (e.g., medical, dental, law, nursing, etc.) experience high levels of stress and depression, the experiences of veterinary medical students have been less well examined. The purpose of this study was to explore the levels of stress and depression among veterinary medical students and to examine the relationship between these variables. Study participants were 1,245 veterinary medical students from North America. The findings provide support for the assertion that veterinary medical students experience high levels of stress and depression. Results also indicated that there is a correlation between stress and depression for veterinary medical students and that female students experience higher levels of stress and depression than their male counterparts.

Cerebral cortical Aß42 and PHF-τ in 325 consecutive brain autopsies stratified by diagnosis, location, and APOE.

We used a novel approach to molecular quantification in standard fixed and embedded tissue to measure amyloid ß 42 (Aß(42)) and paired helical filament-τ (PHF-τ) in frontal, temporal, and parietal cortices from 325 consecutive brain autopsies collected as part of a population-based study of brain aging and incident dementia in the Seattle area. We observed significant effects of APOE ε4 on Aß(42) levels in both diagnostic groups by disease stage and region. In contrast, we did not observe a significant effect of APOE ε4 on PHF-τ levels by disease stage in any region. Levels of Aß(42) and PHF-τ in cerebral cortex were correlated more strongly in the Dementia group, and these measures had independent explanatory power for dementia beyond those of standard neuropathologic indices. Associations between Lewy body disease and Aß(42) or PHF-τ levels and between Aß(42) levels and microvascular brain injury suggested that these comorbid diseases enhanced the penetrance of Alzheimer disease. Our novel approach brings additional insights into the molecular pathogenesis of common causes of dementia and may serve as a platform for future studies pursuing associations between molecular changes in Alzheimer disease and genetic or environmental risk.

Anxiety and depression in transgender individuals: the roles of transition status, loss, social support, and coping.

OBJECTIVE: The purpose of the current study was to examine facilitative and avoidant coping as mediators between distress and transition status, social support, and loss. METHOD: A total of 351 transgender individuals (n = 226 transgender women and n = 125 transgender men) participated in this study. Participants completed measures on transgender identity, family history of mental health concerns, perceptions of loss, coping, depression, and anxiety. RESULTS: The rates of depressive symptoms (51.4% for transgender women; 48.3% for transgender men) and anxiety (40.4% for transgender women; 47.5% for transgender men) within the current study far surpass the rates of those for the general population. Structural equation modeling (SEM) was used to analyze the data-2 separate models were hypothesized, based on reports of anxiety or depression. The SEM results suggest that the processes for transgender women and transgender men are primarily similar for depression and anxiety; avoidant coping served as a mediator between transition status and both distress variables. Social support was directly related to distress variables, as well as indirectly related through avoidant coping. CONCLUSION: Results suggest the need for practitioners to focus on interventions that reduce avoidant coping strategies, while simultaneously increasing social support, in order to improve mental health for transgender individuals. Individuals who are in the beginning stages of their transition will use different coping strategies than those who are in later stages; interventions should be adjusted on the basis of the transition status of transgender clients.

Early mother-child separation, parenting, and child well-being in Early Head Start families.

Drawing on theories of attachment and family instability, this study examined associations between early mother-child separation and subsequent maternal parenting behaviors and children's outcomes in a sample of 2080 families who participated in the Early Head Start Research and Evaluation Project, the vast majority of whom were poor. Multiple regression models revealed that, controlling for baseline family and maternal characteristics and indicators of family instability, the occurrence of a mother-child separation of a week or longer within the first two years of life was related to higher levels of child negativity (at age three) and aggression (at ages three and five). The effect of separation on child aggression at age five was mediated by aggression at age three, suggesting that the effects of separation on children's aggressive behavior are early and persistent.

Fracture toughness of two dentin adhesives.

PURPOSE: Test the hypothesis that a self-etching adhesive is more likely to fail at the dentin-adhesive interface than an etch-and-rinse adhesive. MATERIALS AND METHODS: Forty-eight composite-dentin short rod chevron-notched specimens were prepared. XP Bond and G Bond were used as adhesives. After 7 days in distilled water at 37°C, each specimen was tested (cross-head speed=0.05 mm/min). Fractured surfaces were inspected and characterized as interfacial failures, composite failures or a combination of interfacial and composite failures. The fracture toughness values (K(IC)) of the two adhesives were compared (Student's t-test and Weibull statistics). RESULTS: Of the specimens bonded with XP Bond, 50% failed at the dentin-adhesive interface, 42% at both the dentin-adhesive and composite interface and 8% in the composite alone. Of the specimens bonded with G Bond, 41% failed at the dentin-adhesive interface, 53% at both the dentin-adhesive and composite interface and 6% in the composite alone. The K(IC) values of the two adhesives differed significantly (p<0.05). XP Bond had a K(IC) of 0.77±0.11 MNm(-3/2) (n=17), while G Bond a K(IC) of 0.62±0.21 MNm(-3/2) (n=12). CONCLUSION: The high percentage of mixed failures did not support the hypothesis that the dentin-adhesive interface is clearly less resistant to fracture than the adhesive-composite interface. The finding that cracks occurred in 6-8% in the composite suggests that defects within the composite or at the adhesive-composite interface are important variables to consider in adhesion testing.

Examining the impact of parental risk on family functioning among homeless and housed families.

The present study used data from 132 families that were homeless and a comparison group of 434 housed families in order to compare family functioning across the two groups. Family functioning was assessed by family support workers when the families sought help from one of seven family service agencies in Washington, DC. Multiple regression models showed that there were few differences between homeless and housed families; a difference that did emerge showed that homeless families fared better than housed families in terms of children's developmental stimulation. However, when considering the compounding effects of additional family risk factors, adverse effects of homelessness were observed. As compared with housed families, homeless families with a history of parental mental illness had limited access to support networks and poorer interactions with their children. Poor financial and living conditions were observed among homeless families with histories of substance use. Policy implications and directions for future research are discussed.

The role of home-visiting programs in preventing child abuse and neglect.

Kimberly Howard and Jeanne Brooks-Gunn examine home visiting, an increasingly popular method for delivering services for families, as a strategy for preventing child abuse and neglect. They focus on early interventions because infants are at greater risk for child abuse and neglect than are older children. In their article, Howard and Brooks-Gunn take a close look at evaluations of nine home-visiting programs: the Nurse-Family Partnership, Hawaii Healthy Start, Healthy Families America, the Comprehensive Child Development Program, Early Head Start, the Infant Health and Development Program, the Early Start Program in New Zealand, a demonstration program in Queensland, Australia, and a program for depressed mothers of infants in the Netherlands. They examine outcomes related to parenting and child well-being, including abuse and neglect. Howard and Brooks-Gunn conclude that, overall, researchers have found little evidence that home-visiting programs directly prevent child abuse and neglect. But home visits can impart positive benefits to families by way of influencing maternal parenting practices, the quality of the child's home environment, and children's development. And improved parenting skills, say the authors, would likely be associated with improved child well-being and corresponding decreases in maltreatment over time. Howard and Brooks-Gunn also report that the programs have their greatest benefits for low-income, first-time adolescent mothers. Theorists and policy makers alike believe strongly that home visiting can be a beneficial and cost-effective strategy for providing services to families and children. If home-visiting programs are to have their maximum impact, service providers must follow carefully the guidelines mandated by the respective programs, use professional staff whose credentials are consistent with program goals, intervene prenatally with at-risk populations, and carry out the programs with fidelity to their theoretical models.

Relationship Supportiveness during the Transition to Parenting among Married and Unmarried Parents.

OBJECTIVE: The present study examined trajectories of mothers' and fathers' ratings of the other parent's supportiveness over the first five years after the birth of a child in order to capture the ways in which relationship quality changes for married and unmarried couples during the transition to parenthood. DESIGN: The sample consisted of 2172 mothers and fathers, at least one of whom was experiencing a first birth. Parents were assessed at birth and again when their child was 1, 3, and 5 years old. At each assessment they reported on the emotional supportiveness they received from the other parent as well as their relationship status. RESULTS: Latent growth curve models revealed that for both mothers and fathers, supportiveness tended to be high at birth and decreased steadily thereafter. Furthermore, perceived supportiveness at one year was a better predictor than the same measure at birth in terms of predicting changes in supportiveness over time and whether or not the couple would break up by the child's fifth birthday. Married couples had the most positive trajectories, with higher levels of supportiveness than dating or non-romantic parents and less decline over time than cohabiting couples. Relationship supportiveness also varied by key demographic variables including parental race. CONCLUSION: Reports of partner supportiveness at birth may not be a good indicator of later support or stability. However, by one year postpartum, supportiveness ratings may be more representative of the overall relationship. Family structure is also important in understanding the nature of the transition to parenting among first time parents.

Continuity of paternal social support and depressive symptoms among new mothers.

The present study examined trajectories of paternal support and maternal depressive symptoms over the first two years after the birth of a child. First-time mothers (N = 582) were assessed 6 times during the first 24 months of their child's life. At each assessment they reported on a number of ways in which their child's father provided support, and at three of the assessments, their own depressive symptomatology was assessed. Latent growth curve models revealed that while higher support was related to lower depressive symptomatology, both paternal support and maternal depression tended to decrease over time. The relationships between paternal support and maternal depression are complex and suggest the importance of considering the multiple ways that parents influence one another over time.

Cell phones and the measurement of child neglect: the validity of the parent-child activities interview.

Two multisite studies were conducted to assess the feasibility of using cell phone interviews (the Parent-Child Activities Interview) to learn more about the quality of daily parenting among high-risk mothers, including child neglect. In Study 1, 45 primiparous teenage mothers with 3- to 9-month-old infants were recruited and randomly assigned to two groups: one received frequent cell phone interviews and the other group less frequent interviews over their home telephone. Relationships among paper-and-pencil surveys of parenting (gathered in person) and a Parenting Essentials score (coded from the phone interviews) were significantly correlated. In Study 2, adolescent and adult mothers and their first-born children ( n = 544) completed 2 observations of parenting in their home as well as a series of 3 PCA calls at ages 4 and 8 months. Parenting Essentials coded from the interviews were significantly related to observed measures of parenting at both time points. The Parent-Child Activities Interview shows promise as a reliable and valid measure of parenting, capturing frequent and detailed information about daily parenting practices. Cell phones may prove useful in intervening with mothers at risk of suboptimal parenting and child neglect.

Impact of adherence to concomitant gastroprotective therapy on nonsteroidal-related gastroduodenal ulcer complications.

BACKGROUND & AIMS: The clinical impact of nonadherence to gastroprotective agents (GPAs) coprescribed with anti-inflammatory therapies has not been evaluated. In a large, commercial, managed-care database, we retrospectively characterized the use of GPAs among patients receiving nonselective nonsteroidal anti-inflammatory drugs (ns-NSAIDs) or cyclooxygenase-2-selective inhibitors (coxibs) and determined the impact of nonadherence on the likelihood of gastroduodenal ulcer complications. METHODS: Analyses identified the populations of patients with concomitant histamine-2 receptor antagonist or proton pump inhibitor (PPI) therapy and determined adherence with the prescribed therapy with respect to the duration of anti-inflammatory treatment. Multivariate regression analyses modeled the association between adherence with concomitant protective therapy and the likelihood of upper gastrointestinal (GI) complications including peptic ulcer disease, ulcer, and/or upper-GI bleed. RESULTS: Among 144,203 patients newly prescribed anti-inflammatory therapies, 1.8% received concomitant GPA treatment (ns-NSAIDs, 1.4% vs coxibs, 2.6%; P < .0001). The likelihood of GPA use increased with the presence of risk factors: age older than 65 years (odds ratio [OR], 1.40; 95% confidence interval [CI], 1.3-1.5) and prior history of peptic ulcer disease (OR, 2.5; 95% CI, 1.8-3.3), esophagitis/gastroesophageal reflux (OR, 3.8; 95% CI, 3.5-4.1), ulcer/upper-GI bleed (OR, 1.4; 95% CI, 1.2-1.5), or gastritis (OR, 2.5; 95% CI, 2.2-2.8). Of patients receiving concomitant PPI therapy, 68% had adherence rates of 80% or more. A significantly higher risk of upper-GI ulcers/complications was observed in ns-NSAID patients with adherence rates of less than 80% compared with adherence rates of 80% or more (OR, 2.4; 95% CI, 1.0-5.6), but no such relationship was observed among patients who took coxibs. CONCLUSIONS: Few patients receive concomitant GPA therapy when prescribed anti-inflammatory treatment, although use increased with the presence of risk factors. Adherence to concomitant therapy is paramount to reducing GI events among ns-NSAID users and educational efforts should be undertaken to promote use of and adherence to GPA therapy among these patients.

Fathers' influence in the lives of children with adolescent mothers.

Little is known about the extent, nature, and impact of fathers of children with adolescent mothers. The current study measured father involvement with 134 children of adolescent mothers over the first 10 years of life. Overall, 59% had consistent father contact across the first 8 years. This contact was associated with better socioemotional and academic functioning at 8 and 10 years of age, particularly in school related areas. Children with greater levels of father contact had fewer behavioral problems and had higher scores on reading achievement; these results held after controlling for maternal risk. The findings showed the important role that fathers play in the lives of at-risk children, even if the father does not reside with the child.

Gastrointestinal complications of over-the-counter nonsteroidal antiinflammatory drugs.

This study assessed the "real-world" risk of serious gastrointestinal (GI) toxicities, defined as perforations, ulcers and bleeds (PUBs) in a U.S. representative population that was using two commonly available over-the-counter (OTC) non-selective nonsteroidal antiinflammatory drugs (NSAIDs), naproxen or ibuprofen with or without concomitant aspirin usage. A retrospective review of a commercially available electronic medical record (EMR) database containing the ambulatory health record data for over 3.2 million individuals was conducted. Subjects were eligible for inclusion in the study if they received an OTC dosage of naproxen (220 mg) or ibuprofen (200 mg). An index date for each subject was defined as the first mention of an OTC NSAID in the medication list of the EMR dataset. Subjects were excluded from the analysis if they met any criteria, which can lead to GI bleeding complications. The dataset was analyzed for PUBs, as indicated by the ICD-9 diagnosis codes for gastric, duodenal, peptic, or gastrojejunal ulcers, or GI hemorrhage, as well as the concomitant use of aspirin. A pre/post-analysis was conducted using a case-crossover design with subjects as their own controls. The index date was the defining event, in order to determine the odds ratio associated with OTC NSAID usage. A pre-index time period of 365 days was used for prior PUBs. For the post-index time period, only PUBs that occurred within 90 days of the OTC NSAID index date were considered. The data set contained 11,957 subjects on naproxen and 38,507 subjects on ibuprofen. In both cases, OTC NSAID usage was associated with a statistically significant increase in the odds ratio for PUBs. Subjects on ibuprofen had an odds ratio of 1.38 (95% CI 1.07-1.78, P=0.01). Naproxen subjects exhibited an odds of 1.54 (95% CI 1.04-2.28, P=0.03). The concomitant aspirin population consisted of 2,328 naproxen subjects and 4,843 ibuprofen subjects. Concomitant aspirin usage was also associated with a significantly higher risk for PUBs than the corresponding monotherapy. Subjects taking both ibuprofen and aspirin had an odds ratio of 3.36 (2.36-4.80, P<.00001), while those on naproxen and aspirin had an odds ratio of 2.07 (1.23-3.49, P=.005) relative to those subjects on ibuprofen and naproxen monotherapy, respectively. Utilizing a national electronic medical record database representing patients seen predominantly in a primary care setting, this study has documented the "real-world" risk associated with the use of two common OTC NSAIDs, as well as the increased risk associated with concomitant aspirin use in this population.