Comparison of Central Aortic Pressure between Women with Preeclampsia and Normotensive Postpartum Women from an Urban Region of Western Mexico.

Background and Objectives: Central aortic pressure (CAP) can be measured through noninvasive methods, and CAP wave analysis can provide information about arterial stiffness. The objective of this study was to compare CAP in women with preeclampsia and normotensive postpartum women from an urban region in western Mexico. Materials and Methods: We recruited 78 women in immediate puerperium, including 39 with preeclampsia and 39 with normotension, who received delivery care in our hospital between September 2017 and January 2018. Pulse wave analysis was used to assess central hemodynamics as well as arterial stiffness with an oscillometric device. For this purpose, the measurement of the wave of the left radial artery was obtained with a wrist applanation tonometer and the ascending aortic pressure wave was generated using the accompanying software (V 1.1, Omron, Japan). Additionally, the systolic CAP, diastolic pressure, pulse pressure, heart rate, and rise rate adjusted for a heart rate of 75 bpm were determined. The radial pulse wave was calibrated using the diastolic and mean arterial pressures obtained from the left brachial artery. For all the statistical analyses, we considered p < 0.05 to be significant. Results: The results were as follows: a systolic CAP of 125.40 (SD 15.46) vs. 112.10 (SD 10.12) with p < 0.0001 for women with and without preeclampsia, respectively. Systolic CAP was significantly elevated in women with preeclampsia and could indicate an elevated risk of cardiovascular disease. Conclusion: CAP is an important parameter that can be measured in this group of patients and is significantly elevated in women with postpartum preeclampsia, even when the brachial blood pressure is normal.

Comparación de resultados entre soluciones con y sin formol como medios de fijación y conservación en corazones de Gallus gallus domesticus / Comparison of results between solutions with and without formaldehyde as means of fixation and conservation in Gallus gallus domesticus hearts

RESUMEN: La solución de formol es utilizada en las Escuelas de medicina como medio de fijación y conservación de cadáveres para el estudio de la Anatomía, a la que están expuestos estudiantes, técnicos y personal docente; es alergénica e irritante a las mucosas, y reconocida carcinogénica en humanos por International Agency for Research on Cancer (2006). El objetivo del presente estudio fue comparar resultados cuantitativos y cualitativos entre corazones de Gallus gallus domesticus, luego de aplicarles soluciones con y sin formol. Se formaron dos grupos al azar, a uno se le aplicó solución de formol al 10 %, y al otro solución libre de formol. Se realizaron medidas antropométricas, organolépticas, y de fotografía (Pretest, durante y Postest). Se elaboró base datos en Microsoft Excel (2019), y su procesamiento en SPSS Statistics 2017 Versión 25. Para variables cuantitativas se aplicó la prueba de Shapiro-Wilk, y t-Student pareada. Para variables cualitativas el test Alfa de Cronbach, Chi cuadrado (X2) y los correspondientes coeficientes de asociación (D de Somers y Tau b de Kendal). Los resultados obtenidos de las variables peso, largo, y altura presentaron diferencia estadística significativa (p-valor <0,05), siendo diferente para el ancho y grosor de la pared del ventrículo izquierdo. Las variables color y consistencia presentaron diferencias significativa (p-valor <0,05). El olor irritante a las mucosas estuvo presente durante todo el estudio con la solución con formol. A la inspección, ninguno de los dos grupos presento colonización - descomposición. Se concluye que, los órganos en experimentación que se les aplicó solución libre de formol, presentaron mejores resultados con respecto a los que se les aplico formol al 10 %.

SUMMARY: The formaldehyde solution is used in medical schools as a means of fixing and preserving corpses for the study of Anatomy, to which students, technicians and teaching personnel are exposed; it is allergenic and irritant to the mucosa, and recognized as a human carcinogen by the International Agency for Research on Cancer (2006). The objective of the present study was to compare quantitative and qualitative results between Gallus gallus domesticus hearts, after applying solutions with and without formaldehyde. Two groups were formed at random, to one a 10 % formaldehyde solution was applied, and to the other formaldehyde- free solution. Anthropometric, organoleptic, and photographic measurements were carried out (Pretest, during and Posttest). A database was prepared in Microsoft Excel (2019), and its processing in SPSS Statistics 2017 Version 25. For quantitative variables, the Shapiro-Wilk test and t-Student paired were applied. For qualitative variables the Cronbach's Alpha test, Chi square (X2) and the corresponding association coefficients (Somers D and Kendal's Tau b). The results obtained from the variables weight, length, and height presented a statistically significant difference (p-value <0.05), being different for the width and thickness of the left ventricular wall. The variables color and consistency showed significant differences (p-value <0.05). The irritating smell to the mucous membranes was present throughout the study with the formaldehyde solution. Upon inspection, neither group showed colonization - decomposition. It is concluded that the organs in experimentation that were applied formaldehyde-free solution presented better results compared to those that were applied 10 % formaldehyde.

¿La musicoterapia contribuye a la recuperación posquirúrgica en perras sometidas a ovariosalpingohisterectomía? / Does music therapy contribute to postsurgical recovery in female dogs subjected to ovarian salpingohysterectomy? / A musicoterapia contribui para a recuperação pós cirúrgicas em cadelas submetidas a ovários alpingohisterectomia?

Resumen Con el fin de evaluar la influencia de la musicoterapia como tratamiento coadyuvante en la recuperación de pacientes posquirúrgico, se seleccionaron 20 perras mestizas entre 3 años y 6 meses, con un peso promedio de 10,90 ± 0,58 kg, sin enfermedades preexistentes, las cuales se sometieron a ovariosalpingohisterectomía (OSH) realizada por línea media. Fueron elegidos al azar 10 animales que se sometieron a musicoterapia (T1), mientras que el resto permanecieron como grupo control (T2), con igual alimentación. Se estudiaron las variables dolor (DL) (a través de la escala modificada de Melbourne y Glasgow), frecuencia cardiaca (FC), frecuencia respiratoria (FR), consumo de alimento (CA) y peso final (PF), durante siete días. Las observaciones se analizaron a través de una prueba de T-Student. Los resultados fueron promedios, con efectos estadísticos (p < 0,05), para T1 de 1,49 (DL); 20,85 r. p. m. (FR); 402,66 g (CA) y 12,65 kg (PF). Mientras que para el control (T2) fueron de 6,82 (DL); 28,28 r. p. m. (FR); 357,69 g (CA) y 11,92 kg (PF). Se concluye que la musicoterapia (T1) posquirúrgica en estas condiciones es una alternativa viable en la recuperación del paciente.

Abstract In order to evaluate the influence of music therapy as an adjuvant treatment in the recovery of postoperative patients, 20 mestizo female dogs were selected between 3 years and 6 months of age, with an average weight of 10.90 ± 0.58 kg, without pre-existing conditions, which underwent ovarian salpingohysterectomy (OSH) performed through the midline. Ten randomly selected animals underwent music therapy (T1), while the rest remained as a control group (T2), with the same diet. The variables pain (DL) (using the modified Melbourne and Glasgow scales), heart rate (FC), respiratory frequency (FR), food intake (CA), and final weight (PF) were studied for seven days. The observations were analyzed through a T-Student test. For T1, the results were averages with statistical effects (p < 0.05): 1.49 (DL); 20.85 rpm (FR); 402.66 g (CA), and 12.65 kg (PF). For the control group (T2) they were: 6.82 (DL); 28.28 rpm (FR); 357.69 g (CA), and 11.92 kg (PF). It is concluded that post-surgical music therapy (T1) in these conditions is a viable alternative in patient recovery.

Resumo Com o fim de avaliar a influência da musicoterapia como tratamento coadjuvante na recuperação de pacientes pós cirúrgicos, foram selecionadas 20 cadelas mestiças entre 6 meses e 3 anos, com um peso médio de 10,90 ± 0,58 kg, sem enfermidades preexistentes, as quais foram submetidas a ovários alpingohisterectomia (OSH) realizada por linha média. Foram escolhidos aleatoriamente 10 animais que foram sometidos à musicoterapia (T1), enquanto que o resto permaneceu como grupo controle (T2), com igual alimentação. Foram estudadas as variáveis dor (DL) (através da escala modificada de Melbourne e Glasgow), frequência cardíaca (FC), frequência respiratória (FR), consumo de alimento (CA) e peso final (PF), durante sete días. As observações foram analisadas através de uma prova de T-Student. Os resultados foram em média, com efeitos estatísticos (p < 0,05), para T1 de 1,49 (DL); 20,85 rpm (FR); 402,66 g (CA) e 12,65 kg (PF). Enquanto para o controle (T2) foram de 6,82 (DL); 28,28 rpm (FR); 357,69 g (CA) e 11,92 kg (PF). Se conclui que a musicoterapia (T1) pós cirúrgicas nestas condições é uma alternativa viável na recuperação do paciente.

Development of an ELISA assay to determine neutralising capacity of horse serum following immunisation with Daboia siamensis venom in Myanmar.

Snakebite envenoming is a serious problem in Myanmar. The great majority of snakebite in this country is due to Russell's Viper (Daboia siamensis). For many years, the Burma Pharmaceutical Industry has produced a monovalent antivenom to Russell's Viper in horses. At present, the only way of determining the level of antibody against D. siamensis venom in hyperimmune horse serum is to perform venom neutralisation tests in mice. In this study, we describe the development of an in vitro ELISA assay to estimate neutralising capacity of horse serum. We found a strong correlation between the ELISA assay and the venom neutralisation test in mice (r = 0.982). The assay is robust and has sufficient sensitivity (92%) and specificity (96%) to replace the venom neutralisation test in mice during the immunisation phase in horses.

Estudio de la pareja infertil / Study of the sterile comple

La infertilidad marca a la pareja que la sufre; La pareja infértil se presenta en un estado de angustia y depresión acentuado después de haber realizado un largo y penoso recorrido por las manos de muchos especialistas. El objetivo del presente estudio es revisar las causas de infertilidad en la investigación de la pareja, que se realiza en el departamento de ginecología del Hospital Militar "Dr. Carlos arvelo" de acuerdo a un protocolo de trabajo preestablecido, lo que nos permite llegar a un diagnóstico preciso en el menor tiempo posible y comenzar el tratamiento indicado para corregir la(s) causa(s) de la infertilidad