Artificial intelligence in orthopedic surgery: evolution, current state and future directions.

Technological advances continue to evolve at a breath-taking pace. Computer-navigation, robot-assistance and three-dimensional digital planning have become commonplace in many parts of the world. With near exponential advances in computer processing capacity, and the advent, progressive understanding and refinement of software algorithms, medicine and orthopaedic surgery have begun to delve into artificial intelligence (AI) systems. While for some, such applications still seem in the realm of science fiction, these technologies are already in selective clinical use and are likely to soon see wider uptake. The purpose of this structured review was to provide an understandable summary to non-academic orthopaedic surgeons, exploring key definitions and basic development principles of AI technology as it currently stands. To ensure content validity and representativeness, a structured, systematic review was performed following the accepted PRISMA principles. The paper concludes with a forward-look into heralded and potential applications of AI technology in orthopedic surgery.While not intended to be a detailed technical description of the complex processing that underpins AI applications, this work will take a small step forward in demystifying some of the commonly-held misconceptions regarding AI and its potential benefits to patients and surgeons. With evidence-supported broader awareness, we aim to foster an open-mindedness among clinicians toward such technologies in the future.

Direct effect of common mental disorders on xerostomia in adults estimated by marginal structural models: A population-based study.

OBJECTIVE: To investigate the controlled direct effect (CDE) of common mental disorders (CMD) on xerostomia which is not mediated by psychoactive medication intake. METHODS: A population-based cross-sectional study was conducted with 1720 individuals aged 20-59 years from Florianópolis, Brazil, in 2009. A two-stage cluster sample design was adopted, with a systematic selection of census tracts, followed by a random selection of households. All inhabitants of the selected households belonging to the age group of interest were considered eligible to participate. CMD were assessed using the Self-Reporting Questionnaire (SRQ > 7). Xerostomia was the outcome assessed by asking: "How often do you feel dry mouth?" with responses "often" and "always" taken as indicating xerostomia. Psychoactive medication intake was set as the mediator. Confounding factors included sex, age, per capita family income, educational attainment and smoking status. Marginal structural models were performed to quantify the CDE of CMD on xerostomia. Missing data were handled by multiple imputation by chained equations, and sensitivity analysis for unmeasured confounding was carried out. RESULTS: The overall prevalence of xerostomia was 8.8% and 15.3% of the individuals presented with CMD. After adjustment, the prevalence of xerostomia among individuals with CMD was 3.2 times higher than that among individuals without CMD (PR = 3.2 [95% CI: 2.3; 4.5]). The CDE of CMD on xerostomia which is not mediated by the medication intake resulted in a three times greater prevalence of xerostomia (PR = 3.0 95% CI: 2.0; 4.5) among those individuals with CMD. CONCLUSIONS: Common mental disorders is directly and negatively associated with xerostomia. Clinicians should bear in mind the emotional state when investigating the underlying factors and managing patients with xerostomia.

Effectiveness of operative interventions for hemi or total hip arthroplasty patients who sustain a Vancouver B2 peri-prosthetic femoral fracture: a systematic review protocol.

REVIEW OBJECTIVE: The objective of this review is to identify the effectiveness of operative interventions for individuals who have undergone a hemi or total hip arthroplasty who sustain a Vancouver type B2 peri-prosthetic femoral fracture or equivalent. Specifically, this review will investigate open reduction and internal fixation and femoral revision arthroplasty with or without internal fixation.

Effectiveness of different minimally invasive epiphysiodesis techniques in the management of pediatric leg length discrepancies: a systematic review protocol.

REVIEW QUESTION/OBJECTIVE: The objective of this review is to synthesize the best available evidence on the use of percutaneous epiphysiodesis for the management of pediatric leg length discrepancies (LLDs). The effectiveness of four different percutaneous epiphysiodesis techniques will be compared, including transphyseal screws (percutaneous epiphysiodesis using transphyseal screws), physeal drilling and curettage, physeal stapling and guided growth with eight-Plates.Specific review questions to be addressed include.