[The blood serum lipid spectrum in diabetes mellitus]. / Spektr lipidov syvorotki krovi pri sakharnom diabete.

Investigations of lipid metabolism in patients with disturbed GTT and manifest diabetes mellitus revealed in most cases dyslipidemia, decreasing significantly in the time course of therapy. The results of the investigations showed that the blood levels of cholesterol (CS), beta-lipoproteins, total lipids (TL) and free fatty acids (FFA) in patients with disturbed GTT were significantly increased as compared to healthy persons. In patients with DM of type I, CS, beta-lipoproteins, TL and FFA were significantly lowered after achieving compensation, and in patients with type II DM the above indices except CS and alpha-CS were also lowered. The detected lipid metabolic derangements were noted at the preclinical stage, i.e. in persons with disturbed GTT and were preserved at the stage of manifest forms of DM, necessitating adequate therapy.

[Ultrastructural aspects of preglioma]. / Ul'trastrukturnye aspekty predgliomy.

Investigation of submicroscopic changes in the astrocytes after the intracerebral injection of the carcinogen 9,10-dimethyl-1-2-benzanthracene suggested that the so-called substantial period of preglioma began from the 45th day of the experiment, when structurally atypical astrocytes appeared against the background of distrophic changes. The changes in the submicroscopic organization of the astrocytes during chemical carcinogenesis can be divided into three stages: 1) intracellular hyperplasia due to traumatic injury of the brain; 2) dystrophic changes connected with the vascular tissue disturbances and immediate action of the carcinogen on the tissue; 3) atypical ultrastructure reconstruction of the astrocytes.