RESUMEN
Phytochemical analysis of the MeOH extract of the fruiting bodies of Stropharia aeruginosa resulted in the isolation of three lanostane triterpenoids, aeruginosols A, B and C. The structures of the new compounds were determined by spectroscopic analysis. The biological activities of aeruginosols A, B and C were examined by bioassay with lettuce seedling.
Asunto(s)
Basidiomycota/química , Triterpenos/aislamiento & purificación , Bioensayo , Estructura Molecular , Análisis Espectral , Triterpenos/químicaRESUMEN
Three new lanostane triterpenoids, aeruginosic acid derivatives, were isolated from the fruiting bodies of Stropharia aeruginosa and their structures were determined on the basis of spectral data.
Asunto(s)
Basidiomycota/química , Triterpenos/aislamiento & purificación , Estructura Molecular , Triterpenos/químicaRESUMEN
N-Phenethylhexadecanamide was isolated from the MeOH extract of the fruiting bodies of the mushroom Laetiporus sulphureus together with eburicoic acid. Their structures were elucidated by spectroscopic methods.
Asunto(s)
Ácidos Palmíticos/química , Polyporaceae/química , Lanosterol/análogos & derivados , Lanosterol/química , Estructura MolecularRESUMEN
Three cyclohexenone derivatives, (4S,5S,6S)-5,6-epoxy-4-hydroxy-3-methoxy-5-methyl-cyclohex-2-en-1-one (1), (4R,5R)-4,5-dihydroxy-3-methoxy-5-methyl-cyclohex-2-en-1-one (2), and (4R,5S,6R)-4,5,6-trihydroxy-3-methoxy-5-methyl-cyclohex-2-en-1-one (3), were isolated from unpolished rice fermented with an xylariaceous endophytic fungus (strain YUA-026). The structures of three compounds were established on the basis of spectroscopic analyses and chemical conversion. The minimum inhibitory concentrations of 1 and 3 were 100 microg/ml and 400 microg/ml against Staphylococcus aureus, 100 microg/ml and 200 microg/ml against Pseudomonas aeruginosa, and 200 microg/ml and >400 microg/ml against Candida albicans, respectively. In addition, 1 and 3 exhibited phytotoxic activity against lettuce.
Asunto(s)
Antiinfecciosos/aislamiento & purificación , Basidiomycota/química , Ciclohexanonas/aislamiento & purificación , Antiinfecciosos/farmacología , Candida albicans/efectos de los fármacos , Ciclohexanonas/farmacología , Germinación/efectos de los fármacos , Lactuca/efectos de los fármacos , Pruebas de Sensibilidad Microbiana , Modelos Moleculares , Estructura Molecular , Pseudomonas aeruginosa/efectos de los fármacos , Semillas/efectos de los fármacos , Staphylococcus aureus/efectos de los fármacosRESUMEN
Two sesquiterpenoids, fascicularones A and B, have been isolated from the culture broth of a poisonous mushroom, Naematoloma fasciculare. Their structures were determined using spectroscopic methods.
