RESUMEN
The human T cell lymphotropic virus type 1 (HTLV-1), unlike other RNA viruses such as HIV, has a stable genome and has infected humans since remote times. Although the HTLV-1 infection is endemic in South America, there is scarce information about HTLV-1 in Chile and its history of introduction. This study assessed the genomic content of HTLV-1 from Chile and its relationship with HTLV-1 lineages circulating worldwide by phylogenetic reconstruction and dating analyses. A total of 30 HTLV-1 genomes collected from the four continents were used to conduct dating analyses, including the first HTLV-1 genome from Amerindian/Mapuche ethnicity. Estimation was performed using a Bayesian Markov Chain Monte Carlo coalescent-based approach as implemented in the BEAST program. The time of the most recent ancestor of HTLV-1 from Chile was â¼1409 years ago, which coincides with the period of Amerindian population expansion across South America. Our results suggest HTLV-1aA was possibly introduced in Chile during the migrations of the ancestral indigenous populations.
Asunto(s)
Infecciones por HTLV-I , Virus Linfotrópico T Tipo 1 Humano , Teorema de Bayes , Chile/epidemiología , Virus Linfotrópico T Tipo 1 Humano/genética , Virus Linfotrópico T Tipo 2 Humano/genética , Humanos , Pueblos Indígenas , FilogeniaRESUMEN
Este libro trata de un concepto novedoso: la resiliencia, a la que define como capacidad humana para enfrentar, sobreponerse y ser fortalecido o transformado por experiencias de adversidad. Es un concepto sumamente fértil a la hora de actuar en el campo social, porque desplaza el enfoque tradicional sobre las carencias y los factores de riesgo para situarlo en las fortalezas y la creatividad del individuo y su entorno
RESUMEN
Este libro trata de un concepto novedoso: la resiliencia, a la que define como capacidad humana para enfrentar, sobreponerse y ser fortalecido o transformado por experiencias de adversidad. Es un concepto sumamente fértil a la hora de actuar en el campo social, porque desplaza el enfoque tradicional sobre las carencias y los factores de riesgo para situarlo en las fortalezas y la creatividad del individuo y su entorno
