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1.
Proc Jpn Acad Ser B Phys Biol Sci ; 98(6): 227-282, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35691845

RESUMEN

Presented here are the observations and interpretations from a comprehensive analysis of 16 representative particles returned from the C-type asteroid Ryugu by the Hayabusa2 mission. On average Ryugu particles consist of 50% phyllosilicate matrix, 41% porosity and 9% minor phases, including organic matter. The abundances of 70 elements from the particles are in close agreement with those of CI chondrites. Bulk Ryugu particles show higher δ18O, Δ17O, and ε54Cr values than CI chondrites. As such, Ryugu sampled the most primitive and least-thermally processed protosolar nebula reservoirs. Such a finding is consistent with multi-scale H-C-N isotopic compositions that are compatible with an origin for Ryugu organic matter within both the protosolar nebula and the interstellar medium. The analytical data obtained here, suggests that complex soluble organic matter formed during aqueous alteration on the Ryugu progenitor planetesimal (several 10's of km), <2.6 Myr after CAI formation. Subsequently, the Ryugu progenitor planetesimal was fragmented and evolved into the current asteroid Ryugu through sublimation.


Asunto(s)
Meteoroides , Sistema Solar , Agua
2.
Nature ; 579(7800): 518-522, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-32214245

RESUMEN

Carbonaceous (C-type) asteroids1 are relics of the early Solar System that have preserved primitive materials since their formation approximately 4.6 billion years ago. They are probably analogues of carbonaceous chondrites2,3 and are essential for understanding planetary formation processes. However, their physical properties remain poorly known because carbonaceous chondrite meteoroids tend not to survive entry to Earth's atmosphere. Here we report on global one-rotation thermographic images of the C-type asteroid 162173 Ryugu, taken by the thermal infrared imager (TIR)4 onboard the spacecraft Hayabusa25, indicating that the asteroid's boulders and their surroundings have similar temperatures, with a derived thermal inertia of about 300 J m-2 s-0.5 K-1 (300 tiu). Contrary to predictions that the surface consists of regolith and dense boulders, this low thermal inertia suggests that the boulders are more porous than typical carbonaceous chondrites6 and that their surroundings are covered with porous fragments more than 10 centimetres in diameter. Close-up thermal images confirm the presence of such porous fragments and the flat diurnal temperature profiles suggest a strong surface roughness effect7,8. We also observed in the close-up thermal images boulders that are colder during the day, with thermal inertia exceeding 600 tiu, corresponding to dense boulders similar to typical carbonaceous chondrites6. These results constrain the formation history of Ryugu: the asteroid must be a rubble pile formed from impact fragments of a parent body with microporosity9 of approximately 30 to 50 per cent that experienced a low degree of consolidation. The dense boulders might have originated from the consolidated innermost region or they may have an exogenic origin. This high-porosity asteroid may link cosmic fluffy dust to dense celestial bodies10.

3.
Nat Commun ; 9(1): 2486, 2018 06 27.
Artículo en Inglés | MEDLINE | ID: mdl-29950658

RESUMEN

The near-Earth asteroid (3200) Phaethon is the parent body of the Geminid meteor stream. Phaethon is also an active asteroid with a very blue spectrum. We conducted polarimetric observations of this asteroid over a wide range of solar phase angles α during its close approach to the Earth in autumn 2016. Our observation revealed that Phaethon exhibits extremely large linear polarization: P = 50.0 ± 1.1% at α = 106.5°, and its maximum is even larger. The strong polarization implies that Phaethon's geometric albedo is lower than the current estimate obtained through radiometric observation. This possibility stems from the potential uncertainty in Phaethon's absolute magnitude. An alternative possibility is that relatively large grains (~300 µm in diameter, presumably due to extensive heating near its perihelion) dominate this asteroid's surface. In addition, the asteroid's surface porosity, if it is substantially large, can also be an effective cause of this polarization.

4.
EMBO Mol Med ; 10(5)2018 05.
Artículo en Inglés | MEDLINE | ID: mdl-29666146

RESUMEN

Chronic circadian disruption due to shift work or frequent travel across time zones leads to jet-lag and an increased risk of diabetes, cardiovascular disease, and cancer. The development of new pharmaceuticals to treat circadian disorders, however, is costly and hugely time-consuming. We therefore performed a high-throughput chemical screen of existing drugs for circadian clock modulators in human U2OS cells, with the aim of repurposing known bioactive compounds. Approximately 5% of the drugs screened altered circadian period, including the period-shortening compound dehydroepiandrosterone (DHEA; also known as prasterone). DHEA is one of the most abundant circulating steroid hormones in humans and is available as a dietary supplement in the USA Dietary administration of DHEA to mice shortened free-running circadian period and accelerated re-entrainment to advanced light-dark (LD) cycles, thereby reducing jet-lag. Our drug screen also revealed the involvement of tyrosine kinases, ABL1 and ABL2, and the BCR serine/threonine kinase in regulating circadian period. Thus, drug repurposing is a useful approach to identify new circadian clock modulators and potential therapies for circadian disorders.


Asunto(s)
Relojes Circadianos/efectos de los fármacos , Ritmo Circadiano/efectos de los fármacos , Reposicionamiento de Medicamentos/métodos , Preparaciones Farmacéuticas/administración & dosificación , Animales , Línea Celular Tumoral , Células Cultivadas , Relojes Circadianos/fisiología , Ritmo Circadiano/fisiología , Embrión de Mamíferos/citología , Fibroblastos/citología , Fibroblastos/efectos de los fármacos , Fibroblastos/metabolismo , Humanos , Masculino , Ratones Endogámicos C57BL , Ratones Transgénicos , Inhibidores de Proteínas Quinasas/farmacología , Proteínas Quinasas/metabolismo
5.
Science ; 316(5827): 1011-4, 2007 May 18.
Artículo en Inglés | MEDLINE | ID: mdl-17446355

RESUMEN

High-resolution images of the surface of asteroid Itokawa from the Hayabusa mission reveal it to be covered with unconsolidated millimeter-sized and larger gravels. Locations and morphologic characteristics of this gravel indicate that Itokawa has experienced considerable vibrations, which have triggered global-scale granular processes in its dry, vacuum, microgravity environment. These processes likely include granular convection, landslide-like granular migrations, and particle sorting, resulting in the segregation of the fine gravels into areas of potential lows. Granular processes become major resurfacing processes because of Itokawa's small size, implying that they can occur on other small asteroids should those have regolith.

6.
Nature ; 443(7107): 56-8, 2006 Sep 07.
Artículo en Inglés | MEDLINE | ID: mdl-16957724

RESUMEN

Puzzlingly, the parent bodies of ordinary chondrites (the most abundant type of meteorites) do not seem to be abundant among asteroids. One possible explanation is that surfaces of the parent bodies become optically altered, to become the S-type asteroids which are abundant in the main asteroid belt. The process is called 'space weathering'-it makes the visible and near-infrared reflectance spectrum of a body darker and redder. A recent survey of small, near-Earth asteroids suggests that the surfaces of small S asteroids may have developing stages of space weathering. Here we report that a dark region on a small (550-metre) asteroid-25143 Itokawa-is significantly more space-weathered than a nearby bright region. Spectra of both regions are consistent with those of LL5-6 chondrites after continuum removal. A simple calculation suggests that the dark area has a shorter mean optical path length and about 0.04 per cent by volume more nanophase metallic iron particles than the bright area. This clearly shows that space-weathered materials accumulate on small asteroids, which are likely to be the parent bodies of LL chondrites. We conclude that, because LL meteorites are the least abundant of ordinary (H, L, and LL) chondrites, there must be many asteroids with ordinary-chondrite compositions in near-Earth orbits.

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