Thyrolingual trunk arising from the common carotid bifurcation.

Carotid arteries and their branches exhibit a wide range of variations. However, variations in the origin of the thyrolingual trunk from the common carotid artery are rare. We observed a case of thyrolingual trunk arising from the bifurcation point of the right common carotid artery during a routine dissection class for medical undergraduates. The thyrolingual trunk was running medially and downward before dividing into the upper lingual artery and the lower superior thyroid artery. No such variation was noted from the bifurcation point of the left common carotid artery.

Synthesis and Antimicrobial Screening of Pyrazolo-3-Aryl Quinazolin-4(3H)ones.

2-thio-3-aryl quinazolin-4(3H)one (1) was synthesized by reacting anthranilic acid with thiocarbamate salts of substituted aniline and carbon disulphide, which on reflux with excess of hydrazine hydrate to form 2-hydrazino quinazolin-4(3H)one derivatives (2). The reaction of (2) with variously substituted aryl aldehydes gave the corresponding hydrazones (3). Further, the cyclization of compound (3) in acetic anhydride gave tricyclic pyrazoloquinazolinones (4). All newly synthesized compounds have been tested for their antibacterial activity against gram +ve bacteria B. substilis, S. aureus and gram -ve bacteria E. coli, P. vulgaris. The species used for antifungal activity are Aspergillus niger and Phytophora. Introduction of -OCH3, -OH and -Cl groups to the heterocyclic frame work enhanced antibacterial and antifungal activities.