RESUMEN
Human saliva not only lubricates the oral cavity, making possible functions such as swallowing and speaking, but it also helps to maintain integrity of the hard tissues of the teeth. In addition to secretory immunoglobulins saliva contains several less specific antibacterial systems. This innate defense system includes: lysozyme, lactoferrin, peroxidase system, histatins, mucins, and other polypeptides with basic side chains. Some proteins of innate defense system have bactericidal or bacteriostatic effects; some can cause aggregation of oral bacteria resulting in their increased clearance from oral cavity.
Asunto(s)
Inmunoglobulina A Secretora/inmunología , Boca/inmunología , Saliva/inmunología , Película Dental/inmunología , Histatinas/fisiología , Humanos , Lactoferrina/fisiología , Mucosa Bucal/fisiología , Mucinas/fisiología , Muramidasa/fisiología , Peroxidasa/fisiología , Saliva/fisiología , Glándulas Salivales/metabolismo , Proteínas y Péptidos Salivales/fisiología , Diente/fisiología , alfa-Amilasas/fisiologíaRESUMEN
Results of studies over the recent years indicate that saliva is one of the most important factors which influence on the oral cavity homeostasis. Human saliva not only lubricates the oral tissues, making oral function such as speaking, eating, and swallowing possible, but also protects teeth and oral mucosa surface against influence of many harmful factors. Knowledge about saliva helps to understand pathomechanisms, to work out the prevention and treatment rules of oral cavity diseases.
