Asunto(s)
Fármacos Dermatológicos , Terapia Ultravioleta , Vitíligo/terapia , alfa-MSH/análogos & derivados , Pueblo Asiatico , Terapia Combinada , Método Doble Ciego , Implantes de Medicamentos , Humanos , Factores de Tiempo , Resultado del Tratamiento , Terapia Ultravioleta/efectos adversos , Terapia Ultravioleta/métodos , alfa-MSH/efectos adversos , alfa-MSH/uso terapéuticoAsunto(s)
Atorvastatina/uso terapéutico , Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico , Terapia Ultravioleta , Vitíligo/terapia , Adulto , Terapia Combinada , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Índice de Severidad de la Enfermedad , Método Simple CiegoRESUMEN
BACKGROUND/OBJECTIVES: Controversy persists as to whether lichen planus pigmentosus and ashy dermatosis are separate clinical entities. This study was conducted to examine the clinicopathological features and treatment outcome of the two conditions. METHODS: A retrospective medical chart review of all patients who were diagnosed with lichen planus pigmentosus or ashy dermatosis was conducted. The information collected included the participants' age at onset, site of onset, duration of disease, presence of precipitating factors, distribution of disease, pigmentation and presence of symptoms. In patients from whom a biopsy was taken the histopathological reports were included. RESULTS: Altogether 26 patients with ashy dermatosis and 29 with lichen planus pigmentosus were included in the study. Compared with ashy dermatosis, lichen planus pigmentosus had a more localised distribution with a preponderance for facial involvement, compared with the truncal preponderance in ashy dermatosis. Ashy dermatosis tended to have a more stable clinical course than lichen planus pigmentosus, which was more likely to wax and wane. The utility of histopathology in differentiating between the two conditions is low. CONCLUSION: Ashy dermatosis and lichen planus pigmentosus, as defined in this study, appear to be two separate clinical entities with distinguishable clinical features and natural histories.
Asunto(s)
Hiperpigmentación/tratamiento farmacológico , Liquen Plano/tratamiento farmacológico , Adolescente , Adulto , Anciano , Niño , Progresión de la Enfermedad , Cara , Femenino , Humanos , Hiperpigmentación/etnología , Hiperpigmentación/patología , Liquen Plano/etnología , Liquen Plano/patología , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Torso , Resultado del Tratamiento , Adulto JovenRESUMEN
The term terra firma-forme dermatosis arises from the Latin phrase terra firma, meaning dry land (dirt), thus implying dirt-like dermatosis. The authors highlight five cases of patients with terra firma-forme dermatosis presenting to our dermatology center between 2012 and 2013. All patients presented to the dermatologist for persistent reticulated brown patches on the skin. These patients ranged in age from 6 to 22 years. All patients had tried various cleansing soaps and agents but were unable to remove the patches. The condition was cosmetically unacceptable to the patients and parents. Clinically, these patients had reticulated brown patches. Rubbing 70% isopropyl alcohol wipes on the affected areas demonstrated clearance of the brown pigmented patches in all cases. The diagnosis of terra firma-forme dermatosis (TFFD) was confirmed by forceful rubbing with a gauze pad immersed in 70% isopropyl alcohol or ethyl alcohol. Patients should be reassured about the benign nature of TFFD and educated about the cleaning procedure. Recognition of this condition can assist physicians in making a diagnosis and therapy with a simple alcohol wipe, preventing further unnecessary tests for patients.