Cancer incidence according to the National Health Information Database in Korean patients withend-stage renal disease receiving hemodialysis

Background/Aims@#The aim of this study was to investigate incidence, survival, and risk factors of cancer in end-stage renal disease (ESRD) patients with hemodialysis using information from the National Health Information Database (NHID). @*Methods@#Using the NHID, we identified ESRD patients who started maintenance hemodialysis between 2003 and 2005 in Korea. Patients were followed from initiation of hemodialysis to renal transplantation, death, or December 31, 2016, whichever came first. We calculated the incidence, survival, and risk factors of cancer. @*Results@#Of the total 14,382 ESRD patients, 1,124 (7.82%; men:women, 728:396) werediagnosed with cancer during follow-up. The mean duration from the start of hemodialysis to new cancer identification was 64.40 ± 41.81 months. Significant risk factors for the development of new cancer were old age, male sex, and liver disease. Conversely, patients with diabetes showed low risk for new cancer. The colorectum (17.31%) was the most common primary site of cancer in men, followed by the liver (15.8%), stomach (14.29%), lung (13.6%), and kidney (10.3%). In women, the colorectum (14.65%) was also the most common primary site of cancer, followed by the breast (12.88%), thyroid (12.63%), stomach (10.86%), and lung (8.08%). According to the primary site of cancer, breast cancer showed the longest median survival duration (130.93 months), followed by thyroid, kidney, colorectum, bladder,stomach, liver, and lung cancer. On multivariate analyses, overall survival was affected by age and diabetes. @*Conclusions@#The cancer incidence of chronic hemodialysis patients was relatively high. Thus, careful monitoring and a specific cancer screening program are needed for chronic hemodialysis patients.

Incidence and Prevalence of Idiopathic Inflammatory Myopathies in Korea: a Nationwide Population-based Study

BACKGROUND: This study aimed to estimate the incidence and prevalence of idiopathic inflammatory myopathies (IIM) and associated comorbidities in Korea from 2006 to 2015. METHODS: IIM between 2004 to 2015 were identified using the Korean National Health Insurance Service medical claim database. The case definition required more than one visit based on diagnostic codes including juvenile dermatomyositis (JDM), dermatomyositis (DM), or polymyositis (PM) and registration in the Individual Copayment Beneficiaries Program (ICBP) for rare and intractable diseases. IIM patients with a disease-free period of 24 months before the index date were defined as incident cases. The Elixhauser comorbidity score was calculated. RESULTS: Using the base case definition, 1,150 prevalent patients with IIM (117 JDM, 521 DM, 512 PM) were recorded in 2006 and 2,210 (130 JDM, 1,101 DM, 869 PM) in 2015. The prevalence was estimated at 2.3–4.0 (0.9–1.2 for JDM, 1.2–2.7 for DM, 1.4–2.1 for PM)/100,000 person-year (PY). We identified 218 incident cases of IIM in 2006 (18 JDM, 98 DM, 102 PM) and 191 cases (7 JDM, 83 DM, 101 PM) in 2015. The incidence was estimated at 2.9–5.2 (0.7–1.9 for JDM, 1.8–4.0 for DM, 1.6–3.0 for PM)/1,000,000 PY. The mean age (± standard deviation) of prevalent patients with IIM was 51.2 (± 16.9) years, and the percentage of women was 72.1%. More than two-thirds of patients (70.7%) had more than two comorbidities. Twenty percent of patients had interstitial lung diseases. CONCLUSION: In Korea, the incidence and prevalence of IIM were 2.9–5.2/1,000,000 PY and 2.3–4.0/100,000 PY, respectively.

Validity Evidences for the Dimensional Clinical Personality Inventory in Outpatient Psychiatric Sample / Evidências de Validade do Inventário Dimensional Clínico da Personalidade em Amostra Psiquiátrica / Evidencias de Validez del Inventario Dimensional Clínico de Personalidad en Muestra Psiquiátrica

The Dimensional Clinical Personality Inventory (IDCP) was developed in Brazil for the assessment of pathological personality traits. This study aimed to seek validity evidence for the dimensions of IDCP based on external criteria, psychiatric diagnosis. We examined the profile in IDCP of 105 psychotherapy outpatients, previously diagnosed with personality disorders. The profiles were compared with the profile of the normative non-clinical sample and we conducted the repeated measures analysis to investigate whether the IDCP is able to discriminate consistent profiles for different diagnoses and compared the general population. The results suggest validity evidence based on external criteria for the IDCP dimensions and points to the clinical effectiveness of the instrument.(AU)

Foi desenvolvido no Brasil o Inventário Dimensional Clínico da Personalidade (IDCP) para avaliação das características patológicas da personalidade. O presente estudo buscou evidências de validade com base em critério externo, diagnóstico psiquiátrico, das dimensões do IDCP. Examinou-se o perfil no IDCP de 105 pacientes de ambulatório de psicoterapia, previamente diagnosticados com transtornos da personalidade. Comparou-se o perfil no IDCP da amostra clínica com o perfil da amostra normativa não clínica e realizou-se o procedimento de análise de perfis por medidas repetidas visando investigar se o IDCP é capaz de discriminar perfis coerentes para os distintos diagnósticos e em comparação à população geral. Os resultados sugerem evidências de validade com base no critério externo para as dimensões do IDCP, bem como aponta para a utilidade clínica do instrumento.(AU)

El Inventario Dimensional Clínico del Personalidad (IDCP) fue desarrollado en Brasil para evaluación del el IDCP prueba. Este estudio tuvo como objetivo buscar evidencias de validez en base a criterios externos, diagnóstico psiquiátrico, a un instrumento para la evaluación de los trastornos de personalidad típica síntomas, el IDCP. Examinamos el perfil en IDCP de 105 pacientes de la clínica de psicoterapia, previamente diagnosticados con trastornos de la personalidad. Los perfiles se compararon con el perfil de la muestra no clínica normativa y que se llevó a cabo el análisis de medidas repetidas para investigar si el IDCP es capaz de discriminar los perfiles consistentes para diferentes diagnósticos en comparación con la población general. Los resultados sugieren evidencia de validez sobre la base de criterios externos a dimensiones del IDCP y puntos para la utilidad clínica del instrumento.(AU)

Validity evidences for the dimensional clinical personality inventory in outpatient psychiatric sample / Evidências de validade do inventário dimensional clínico da personalidade em amostra psiquiátrica / Evidencias de validez del inventario dimensional clínico de personalidad en muestra psiquiátrica

The Dimensional Clinical Personality Inventory (IDCP) was developed in Brazil for the assessment of pathological personality traits. This study aimed to seek validity evidence for the dimensions of IDCP based on external criteria, psychiatric diagnosis. We examined the profile in IDCP of 105 psychotherapy outpatients, previously diagnosed with personality disorders. The profiles were compared with the profile of the normative non-clinical sample and we conducted the repeated measures analysis to investigate whether the IDCP is able to discriminate consistent profiles for different diagnoses and compared the general population. The results suggest validity evidence based on external criteria for the IDCP dimensions and points to the clinical effectiveness of the instrument.

Foi desenvolvido no Brasil o Inventário Dimensional Clínico da Personalidade (IDCP) para avaliação das características patológicas da personalidade. O presente estudo buscou evidências de validade com base em critério externo, diagnóstico psiquiátrico, das dimensões do IDCP. Examinou-se o perfil no IDCP de 105 pacientes de ambulatório de psicoterapia, previamente diagnosticados com transtornos da personalidade. Comparou-se o perfil no IDCP da amostra clínica com o perfil da amostra normativa não clínica e realizou-se o procedimento de análise de perfis por medidas repetidas visando investigar se o IDCP é capaz de discriminar perfis coerentes para os distintos diagnósticos e em comparação à população geral. Os resultados sugerem evidências de validade com base no critério externo para as dimensões do IDCP, bem como aponta para a utilidade clínica do instrumento.

El Inventario Dimensional Clínico del Personalidad (IDCP) fue desarrollado en Brasil para evaluación del el IDCP prueba. Este estudio tuvo como objetivo buscar evidencias de validez en base a criterios externos, diagnóstico psiquiátrico, a un instrumento para la evaluación de los trastornos de personalidad típica síntomas, el IDCP. Examinamos el perfil en IDCP de 105 pacientes de la clínica de psicoterapia, previamente diagnosticados con trastornos de la personalidad. Los perfiles se compararon con el perfil de la muestra no clínica normativa y que se llevó a cabo el análisis de medidas repetidas para investigar si el IDCP es capaz de discriminar los perfiles consistentes para diferentes diagnósticos en comparación con la población general. Los resultados sugieren evidencia de validez sobre la base de criterios externos a dimensiones del IDCP y puntos para la utilidad clínica del instrumento.