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1.
S Afr Med J ; 110(9): 850-854, 2020 Aug 31.
Artículo en Inglés | MEDLINE | ID: mdl-32880266

RESUMEN

While adolescent mothers' postpartum return to school offers long-term benefits, returning too early in the absence of sufficient support may impede the healthy development of their children. This study assessed the rates of adolescent mothers' return to school in South Africa (SA) and examined how many months after birth school-aged girls resumed schooling. Two independent studies recruited 1 114 adolescent mothers in Eastern Cape Province and Durban, respectively. Across the two studies, 64.7% (n=649) and 47.8% (n=53) of mothers, respectively, had returned to school at the time of the study. Of these mothers, the majority had returned to school within the first 2 months post partum (study 1: 67.6%; n=439; and study 2: 58.5%; n=31), fewer between 2 and 6 months (16.9%; n=110; and 22.6%; n=12), and after 12 months (2.0%; n=13; and unknown). Our findings indicate a mismatch between SA's national policy recommendations and actual return patterns, showing that a large proportion of mothers returned to school much earlier than advised. This study also highlights a particular need to amend school policies that support early-returners and their children. Additional research on the needs of mother-child dyads and studies on the impact of different timescales on educational and health outcomes are needed to further inform policy and practice regarding adolescent mothers' return to school.


Asunto(s)
Madres/estadística & datos numéricos , Embarazo en Adolescencia , Regreso a la Escuela/estadística & datos numéricos , Adolescente , Femenino , Humanos , Madres/educación , Parto , Proyectos Piloto , Políticas , Embarazo , Población Rural , Sudáfrica , Encuestas y Cuestionarios , Factores de Tiempo , Población Urbana , Adulto Joven
2.
Nervenarzt ; 84(4): 498-507, 2013 Apr.
Artículo en Alemán | MEDLINE | ID: mdl-23325312

RESUMEN

BACKGROUND: The correlation between detection of autoantibodies and the pattern and severity of symptoms in patients with encephalitis was the crucial factor for the initiation of immune therapy. The elimination of autoantibodies using therapeutic apheresis by plasma exchange (PE) and immunoadsorption (IA) is a pathophysiologically guided therapeutic approach. The aim was to evaluate the current use of PE and for the first time also of IA for patients with autoimmune encephalitis. METHODS: A nationwide data collection was performed and the modified Rankin score (mRS) was used to evaluate the severity of neurological symptoms. RESULTS: Data of 31 treatment courses (30 patients and 1 relapse) were documented and 22 patients were positive for autoantibodies (NMDA-R, GABA, VGKC, Hu). In 23 cases PA was performed, tryptophan IA in 7 cases and in 1 patient both methods were applied. In 67 % of the treatment courses the mRS improved and the mean mRS of all patients was 3.2 before apheresis and 2.2 after apheresis (p < 0.05). All patients who were treated with IA improved clinically from a mean mRS of 3.9 before IA to 1.9 after IA (p < 0.01). CONCLUSIONS: For immune-mediated forms of encephalitis rapid elimination of autoantibodies with PA and IA seems to be an effective therapeutic option as part of a multimodal immune therapy and is already established in many clinics in Germany.


Asunto(s)
Autoanticuerpos/aislamiento & purificación , Eliminación de Componentes Sanguíneos/métodos , Encefalopatías/epidemiología , Encefalopatías/terapia , Enfermedad de Hashimoto/epidemiología , Enfermedad de Hashimoto/terapia , Sistema de Registros , Adolescente , Adulto , Distribución por Edad , Anciano , Autoanticuerpos/inmunología , Encefalopatías/inmunología , Encefalitis , Femenino , Alemania/epidemiología , Enfermedad de Hashimoto/inmunología , Humanos , Masculino , Persona de Mediana Edad , Prevalencia , Estudios Retrospectivos , Factores de Riesgo , Distribución por Sexo , Resultado del Tratamiento , Adulto Joven
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