A Punishing Look: Skin Tone and Afrocentric Features in the Halls of Justice.

Two related lines of research have gained traction in the social sciences during the past three decades. One examines the association between race and punishment, while a second investigates stratification and colorism, defined as discrimination based on skin tone. Yet rarely do scholars examine these issues together. The current study uses new data to investigate the association between offender's skin tone, Afrocentric facial features, and criminal punishment. More than 850 booking photos of black and white male offenders in two Minnesota counties were coded and then matched to detailed sentencing records. Results indicate that darker skin tone and Afrocentric facial features are associated with harsher sanctions and that the latter effect is particularly salient for white defendants. The findings add to existing work on skin tone and stratification and suggest that future research should consider other aspects of appearance, such as facial features, in the study of punishment and inequality.

Cellular responses of eastern oysters, Crassostrea virginica, to titanium dioxide nanoparticles.

Because of the continued development and production of a variety of nanomaterials and nanoparticles, their uptake and effects on the biota of marine ecosystems must be investigated. Filter feeding bivalve molluscs are highly adapted for capturing particles from the external environment and readily internalize nano- and micro-sized particles through endocytosis, so they are commonly used as valuable indicator species for nanoparticle studies. In these studies, adult eastern oysters, Crassostrea virginica, were exposed to a range of titanium dioxide nanoparticle (TiO2-NP) concentrations (5, 50, 500, and 5000 µg/L) in conjunction with natural sunlight. Isolated hepatopancreas tissues were also exposed to the same TiO2-NP concentrations using particles exposed to similar light and dark conditions. Dose-dependent decreases in lysosomal stability were observed in the adult oyster studies as well as in the isolated tissues, at exposures as low as 50 µg/L. Titanium accumulation in isolated hepatopancreas tissue studies was directly correlated to lysosomal destabilization. Based on measurements of lipid peroxidation as an indicator of oxidative stress, TiO2-NPs toxicity was not related to increased ROS production over the short-term course of these exposures. Analysis of particle size using dynamic light scattering (DLS) indicated that concentration had a significant impact on agglomeration rates, and the small agglomerates as well as individual particles are readily processed by oysters. Overall, this study illustrates that low concentrations of TiO2-NPs may cause sublethal toxicity on oysters, which might be enhanced under natural sunlight conditions. In estuarine environments, where these nanomaterials are likely to accumulate, agglomeration rates, interaction with organics, and responses to sunlight are critical in determining the extent of their bioreactivity and biological impacts.

Systematic review of clinical studies examining biomarkers of brain injury in athletes after sports-related concussion.

The aim of this study was to systematically review clinical studies examining biofluid biomarkers of brain injury for concussion in athletes. Data sources included PubMed, MEDLINE, and the Cochrane Database from 1966 to October 2013. Studies were included if they recruited athletes participating in organized sports who experienced concussion or head injury during a sports-related activity and had brain injury biomarkers measured. Acceptable research designs included experimental, observational, and case-control studies. Review articles, opinion papers, and editorials were excluded. After title and abstract screening of potential articles, full texts were independently reviewed to identify articles that met inclusion criteria. A composite evidentiary table was then constructed and documented the study title, design, population, methods, sample size, outcome measures, and results. The search identified 52 publications, of which 13 were selected and critically reviewed. All of the included studies were prospective and were published either in or after the year 2000. Sports included boxing (six studies), soccer (five studies), running/jogging (two studies), hockey (one study), basketball (one study), cycling (one study), and swimming (one study). The majority of studies (92%) had fewer than 100 patients. Three studies (23%) evaluated biomarkers in cerebrospinal fluid (CSF), one in both serum and CSF, and 10 (77%) in serum exclusively. There were 11 different biomarkers assessed, including S100ß, glial fibrillary acidic protein, neuron-specific enolase, tau, neurofilament light protein, amyloid beta, brain-derived neurotrophic factor, creatine kinase and heart-type fatty acid binding protein, prolactin, cortisol, and albumin. A handful of biomarkers showed a correlation with number of hits to the head (soccer), acceleration/deceleration forces (jumps, collisions, and falls), postconcussive symptoms, trauma to the body versus the head, and dynamics of different sports. Although there are no validated biomarkers for concussion as yet, there is potential for biomarkers to provide diagnostic, prognostic, and monitoring information postinjury. They could also be combined with neuroimaging to assess injury evolution and recovery.

Mindful attention increases and mediates psychological outcomes following mantram repetition practice in veterans with posttraumatic stress disorder.

BACKGROUND: Several evidence-based treatments are available to veterans diagnosed with posttraumatic stress disorder (PTSD). However, not all veterans benefit from these treatments or prefer to engage in them. OBJECTIVES: The current study explored whether (1) a mantram repetition program (MRP) increased mindful attention among veterans with PTSD, (2) mindful attention mediated reduced PTSD symptom severity and enhanced psychological well-being, and (3) improvement in mindful attention was due to the frequency of mantram repetition practice. RESEARCH DESIGN: Data from a randomized controlled trial comparing MRP plus treatment as usual (MRP+TAU) or TAU were analyzed using hierarchical linear models. SUBJECTS: A total of 146 veterans with PTSD from military-related trauma were recruited from a Veterans Affairs outpatient PTSD clinic (71 MRP+TAU; 75 TAU). MEASURES: The Clinician Administered PTSD Scale (CAPS), PTSD Checklist (PCL), the Brief Symptom Inventory-18 depression subscale, Health Survey SF-12v2, and Mindfulness Attention Awareness Scale (MAAS) were used. Frequency of mantram repetition practice was measured using wrist-worn counters and daily logs. RESULTS: Intent-to-treat analyses indicated greater increases in mindful attention, as measured by the MAAS, for MRP+TAU as compared with TAU participants (P<0.01). Mindful attention gains mediated previously reported treatment effects on reduced PTSD symptoms (using both CAPS and PCL), reduced depression, and improved psychological well-being. Frequency of mantram repetition practice in turn mediated increased mindful attention. CONCLUSIONS: The MRP intervention and specifically, mantram practice, improved mindful attention in veterans with PTSD, yielding improved overall psychological well-being. MRP may be a beneficial adjunct to usual care in veterans with PTSD.

Chapter 5 mantram repetition: an evidence-based complementary practice for military personnel and veterans in the 21st century.

Today in the digital age, with our advances in modern technology and communication, there are additional stressors for our military personnel and Veterans. Constant dangers exist both on and off the battlefield, unlike prior wars that had clearly-defined war zones. In addition, medical advances have assisted in saving the lives of many more gravely injured troops than ever previously possible. As the wars in Iraq and Afghanistan come to an end, large numbers of service men and women are returning home with multiple injuries. This group of Veterans has significantly higher rates of posttraumatic stress disorder (PTSD) and traumatic brain injury than ever before reported. Although existing PTSD therapies have been found to be highly effective for many Veterans, there is a substantial minority unsatisfactorily treated. Mantram repetition, an innovative, complementary, evidence-based treatment, is proving to be successful for these new Veterans. When used regularly it helps with "road rage, impatience, anger, frustration, and being out of control." A mantram is a brief, sacred word or phrase that embodies divine power or the greatest positive energy one can imagine (Easwaran, 2008a). Mantram repetition is a simple, quick, personal, portable, and private complementary practice that may be used as an adjunct to current treatments for PTSD. Growing research evidence supports mantram repetition's value for dissemination and adoption in the 21st century. This chapter summarizes Mantram Program research conducted from 2003 to 2014. It describes the health-related benefits of the Mantram Program in various populations. The current research focuses on benefits for managing psychological distress and promoting quality of life in Veterans. Future areas for research are suggested.

Cogmed working memory training product review.

OBJECTIVE: In this review of the Cogmed training program, we discuss its theoretical foundations, materials, the intervention program, use of coaches, customer support, and research support. METHOD: This review was conducted by means of first-hand exploration of the Cogmed training program in conjunction with a critical synthesis of existing empirical literature. RESULTS: We conclude that Cogmed has the potential to help individuals improve working memory capabilities and focused attention. CONCLUSION: More research is needed to demonstrate if these changes in working memory and focused attention are enduring and generalizable.

Effect of exogenous IGF-1 on chondrocyte apoptosis in a rabbit intraarticular osteotomy model.

Insulin-like growth factor-1 (IGF-1) has been shown to protect chondrocytes from apoptosis in vitro. IGF-1 expression may also assist in maintaining a fully differentiated chondrocyte phenotype. Theoretically, posttraumatic administration of IGF-1 may inhibit chondrocyte apoptosis. This study is to determine if administration of IGF-1 after fracture inhibits apoptosis in vivo. Twenty-four mature female New Zealand white rabbits were randomized to control and IGF-1 groups. All subjects underwent standardized medial femoral condyle fracture and repair. Fibrin clot was administered in all subjects, with 25 mcg/ml IGF-1 in the clot in half the subjects. Half of the animals in each group were sacrificed at 2 weeks and half at 4 weeks, specimens were fixed and underwent TUNEL staining. Two-week controls showed significantly higher rate of apoptosis than 2-week IGF-1 subjects (21 +/- 6 vs. 12 +/- 6, p = 0.04). Likewise, 4-week controls showed significantly higher rate of apoptosis than 2-week IGF-1 subjects (23 +/- 7 vs. 10 +/- 2, p = 0.01). There was no significant administration difference between 2-week control and 4-week control subjects, or between 2-week IGF-1 and 4-week IGF-1 subjects. Intraarticular IGF-1 at the time of fracture repair appears to inhibit chondrocyte apoptosis in vivo, as judged by TUNEL staining, in this animal model. If administration of IGF-1 inhibits human chondrocyte apoptosis in vivo, this may lead to interventions that may reduce posttraumatic arthritis after fracture.

Dissociable effects of conscious emotion regulation strategies on explicit and implicit memory.

The authors manipulated emotion regulation strategies at encoding and administered explicit and implicit memory tests. In Experiment 1, participants used reappraisal to enhance and decrease the personal relevance of unpleasant and neutral pictures. In Experiment 2, decrease cues were replaced with suppress cues that directed participants to inhibit emotion-expressive behavior. Across experiments, using reappraisal to enhance the personal relevance of pictures improved free recall. By contrast, attempting to suppress emotional displays tended to impair recall, especially compared to the enhance condition. Using reappraisal to decrease the personal relevance of pictures had different effects depending on picture type. Paired with unpleasant pictures, the decrease cue tended to improve recall. Paired with neutral stimuli, the decrease cue tended to impair recall. Emotion regulation did not affect perceptual priming. Results highlight dissociable effects of emotion regulation on explicit and implicit memory, as well as dissociations between regulation strategies with respect to explicit memory.

Elimination of background in film-based applications.

Erase-It Background Eliminator is a solution used directly on processed film to remove background or improve data resolution. Traditional methods, such as optimization of the scientific protocol or better estimation of exposure time, are tedious and uncertain. Nevertheless, autoradiography continues to be a simple, effective method to visualize data. Therefore, we evaluated the ability of Erase-It Working Solution to help solve background and resolution issues. To demonstrate the efficiency of the Background Eliminator, we analyzed the product's ability to remove signal evenly, performance on several brands of film, and usefulness with various detection methods. Even reduction of signal was demonstrated by performing densitometric analysis on film generated from a dot blot with serial dilutions of analyte. In addition, overexposed films from various suppliers were effectively treated to remove background and visualize data. Autoradiographs, generated with 32P-labeled probes, and chemiluminescent substrate were also processed resulting in clearer images. Our results demonstrate that film data can be treated quickly and conveniently without fear of artificial enhancement. We show the Background Eliminator to be a universal and timesaving tool to visualize results that otherwise may be difficult to interpret.